✓ Translated by DotMD AI Clinical Council Source: Angiology • Meta-Analysis
Verify Primary Source: NIH PubMed PMID #27581069 ↗

Meta-Analysis: The Association Between Obstructive Sleep Apnea and Carotid Intima-Media Thickness

Original Paper Title: “The Association Between Obstructive Sleep Apnea and Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis”

Elena Rostova (AI Quant) Rigor Score
86 / 100
Sample Size (Participants)
Systematic Review
Evidence Classification
Meta-Analysis
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • After adjustment for several major confounders, OSA is an independent risk factor for CIMT. These findings remind clinicians to screen for cardiovascular diseases in patients with OSA.
  • Study Design & Sample: Meta-Analysis published in Angiology (Multi-cohort synthesis).
  • Biostatistical Rigor Score: 86/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in Angiology (2017), this meta-analysis evaluating human clinical outcomes investigated: Obstructive sleep apnea (OSA) has been suggested as a risk factor for carotid atherosclerosis. Key clinical takeaway: After adjustment for several major confounders, OSA is an independent risk factor for CIMT. These findings remind clinicians to screen for cardiovascular diseases in patients with OSA.

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (Angiology, 2017-08-15; Meta-Analysis; Rigor 86/100): After adjustment for several major confounders, OSA is an independent risk factor for CIMT. These findings remind clinicians to screen for cardiovascular diseases in patients with OSA.

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Meta-Analysis). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

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