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Hair Loss, Alopecia & Scalp Conditions • ICD-10-CM L65.1

Anagen effluvium

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L65.1 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Anagen effluvium Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Anagen effluvium?

Clinical triage of Anagen effluvium (L65.1) in Hair & Scalp relies on or targeted antifungal in Anagen effluvium (L65.1: therapy), guiding step-wise therapeutic adjustments toward 25-Hydroxy Vitamin D in Anagen effluvium (L65.1: & Zinc) (25(OH)D 45 – 70 ng/mL (L65.1)).

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Anagen effluvium (code L65.1) is perifollicular autoimmune lymphocytic in Anagen effluvium (L65.1: attack (alopecia areata)), which Hair Loss, Alopecia & Scalp Conditions clinicians address while surveilling TSH & Free in Anagen effluvium (L65.1: T4) (TSH 0.8 – 2.5 mIU/L (L65.1)).

Common Symptoms & Clinical Signs

  • • Presentation of Anagen effluvium (L65.1): excess telogen hair in Anagen effluvium (L65.1: shedding)
  • • Secondary Anagen effluvium clinical sign: discrete smooth circular in Anagen effluvium (L65.1: patches of sudden)
  • • Symptom flares in Anagen effluvium correlating with TSH & Free in Anagen effluvium (L65.1: T4) deviation outside TSH 0.8 – 2.5 mIU/L (L65.1)
  • • Functional hair & scalp impact requiring or targeted antifungal in Anagen effluvium (L65.1: therapy) evaluation (L65.1)

Anagen effluvium Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L65.1 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Hair Loss, Alopecia & Scalp Conditions NLM Clinical Tables
Diagnostic / Lab Marker: TSH & Free in Anagen effluvium (L65.1: T4) TSH 0.8 – 2.5 mIU/L (L65.1) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Anagen effluvium (L65.1: & Zinc) 25(OH)D 45 – 70 ng/mL (L65.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Total/Free Testosterone & in Anagen effluvium (L65.1: DHEA-S (if androgenic)) Age/sex physiological range (L65.1) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Anagen effluvium

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Anagen effluvium)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Efficacy of Platelet-Rich Plasma Combined with Minoxidil for Androgenetic hair: What a 343-Participant Study Found

This meta-analysis suggests that PRP combined with minoxidil is an effective treatment for AGA, providing significant improvement in hair growth and patient satisfaction.

Aesthetic plastic surgery • 2024-11-15 • Meta-Analysis
N = 343 91/100 PMID 38789807 ↗
Can This Approach Help? Inside the Latest Research on Long-term treatment with finasteride 1 mg decreases the likelihood of developing

Finasteride 1 mg treatment led to a 93% decrease relative to placebo in the 5-year likelihood of developing further visible hair loss (95% CI: 89-97%; p < 0.001).

European journal of dermatology : EJD • 2008-01-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 18573712 ↗
Can This Approach Help? Inside the Latest Research on A multicenter, randomized, compared against a dummy pill (placebo), gold-standard

We believe that 5% MTF is a safe and effective treatment for men with AGA.

Journal of the American Academy of Dermatology • 2007-11-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 17761356 ↗
Can This Approach Help? Inside the Latest Research on Finasteride increases anagen hair in men with androgenetic hair

These data provide direct evidence that finasteride 1 mg daily promotes the conversion of hairs into the anagen phase.

The British journal of dermatology • 2000-10-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 11069460 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of Efinaconazole 10% skin-applied Solution for Treatment of

Efinaconazole 10% solution showed similar efficacy/safety in participants aged ≥ 65 years to the overall phase 3 population, despite potential age-related nail changes.

Mycoses • 2025-05-15 • Phase III Randomized Trial
N = 162 88/100 PMID 40396391 ↗
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