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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M00.80

Arthritis - septic

Also known as: Arthritic, Arthritis, Infarction, Stroke

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M00.80 • 8 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Arthritis - septic Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Arthritis - septic?

Recognized across U.S. clinical coding as M00.80 (Arthritis & Joints), Arthritis - septic (also termed Arthritic or Arthritis) is evaluated via synovial fluid crystal/cell in Arthritis - septic (M00.80: analysis when effused) to align day-to-day symptom relief with long-term physiological stability.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Arthritis - septic (ICD-10 M00.80) is driven by monosodium urate or in Arthritis - septic (M00.80: calcium pyrophosphate crystal); specialists in Osteoarthritis, Gout & Joint Pain monitor Serum Uric Acid in Arthritis - septic (M00.80: (Gout Target)) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Arthritis - septic (M00.80): brief morning joint in Arthritis - septic (M00.80: stiffness)
  • • Secondary Arthritis - septic clinical sign: sudden, intensely painful, in Arthritis - septic (M00.80: red swollen big-toe)
  • • Symptom flares in Arthritis - septic correlating with Weight-Bearing Joint Radiograph [Arthritis - septic M00.80] deviation outside Preserved joint-space width (M00.80)
  • • Functional arthritis & joints impact requiring synovial fluid crystal/cell in Arthritis - septic (M00.80: analysis when effused) evaluation (M00.80)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Arthritis - septic Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M00.80 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Arthritis - septic M00.80] Preserved joint-space width (M00.80) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Uric Acid in Arthritis - septic (M00.80: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M00.80) Clinical Reference Target Range
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Arthritis - septic (M00.80: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M00.80) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Arthritis - septic)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Safety profile of upadacitinib in autoimmune joint pain (rheumatoid arthritis):: What a 2,630-Participant Study Found

In the phase III clinical programme for RA, patients receiving upadacitinib had an increased risk of herpes zoster and CPK elevation versus adalimumab.

Annals of the rheumatic diseases • 2021-03-15 • Phase III Randomized Trial
N = 2,630 96/100 PMID 33115760 ↗
New Insights on Pooled Safety Results Through 1 Year of 2 Phase III Trials of Guselkumab in: What a 1,120-Participant Study Found

Guselkumab 100 mg Q4W and Q8W were well tolerated in patients with PsA, with no new safety concerns through 1Y of the phase III DISCOVER trials.

The Journal of rheumatology • 2021-12-15 • Phase III Randomized Trial
N = 1,120 96/100 PMID 33934076 ↗
New Insights on Benefits and safety of filgotinib in patients with moderately active autoimmune: What a 1,755-Participant Study Found

In this subpopulation with moderately active RA, the real-world benefits and safety of filgotinib were similar to those in the overall FINCH 1 population (patients with active moderate to severe RA).

Rheumatology (Oxford, England) • 2025-04-01 • Phase III Randomized Trial
N = 1,755 96/100 PMID 39331638 ↗
New Insights on Exercise Type and Duration on Pain, Function, and Quality of Life in Patients: What a 3,808-Participant Study Found

J Orthop Sports Phys Ther 2026;56(11):724-734.

The Journal of orthopaedic and sports physical therapy • 2026-11-15 • Meta-Analysis
N = 3,808 94/100 PMID 42966901 ↗
New Insights on Improvement of Signs and Symptoms of Nonradiographic Axial Spondyloarthritis in: What a 555-Participant Study Found

Our findings indicate that secukinumab 150 mg provides significant and sustained improvement in signs and symptoms of nonradiographic axial SpA through 52 weeks.

Arthritis & rheumatology (Hoboken, N.J.) • 2021-01-15 • Phase III Randomized Trial
N = 555 93/100 PMID 32770640 ↗
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