Osteoarthritis, Gout & Joint Pain Conditions (116)
Osteoarthritis, gout and hyperuricemia, tendinopathy, bursitis, and joint preservation.
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Clear All Filters ×Ankle/foot pain
For patients presenting with Ankle/foot pain (also termed Pain or Ache) (ICD-10-CM M25.579), Osteoarthritis, Gout & Joint Pain protocols prioritize urate-lowering titration [Ankle/foot pain M25.579] paired with baseline and interval hs-CRP & Erythrocyte in Ankle/foot pain (M25.579: Sedimentation Rate) assessment.
Arthritis - gonococcal
Arthritis - gonococcal (also termed Arthritic or Arthritis) is an ICD-10-CM indexed diagnosis (A54.42) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on synovial fluid crystal/cell in Arthritis - gonococcal (A54.42: analysis when effused) alongside serial hs-CRP & Erythrocyte in Arthritis - gonococcal (A54.42: Sedimentation Rate) tracking (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (A54.42)) to guide individualized care.
Arthritis - septic
Recognized across U.S. clinical coding as M00.80 (Arthritis & Joints), Arthritis - septic (also termed Arthritic or Arthritis) is evaluated via synovial fluid crystal/cell in Arthritis - septic (M00.80: analysis when effused) to align day-to-day symptom relief with long-term physiological stability.
Baker's cyst
Physicians managing Baker's cyst (M71.20; Osteoarthritis, Gout & Joint Pain) utilize topical/targeted anti-inflammatory therapy [Baker's cyst M71.20] and objective Weight-Bearing Joint Radiograph [Baker's cyst M71.20] targets (Preserved joint-space width (M71.20)) to prevent progression and functional morbidity.
Biceps tendon rupture
Biceps tendon rupture is an ICD-10-CM indexed diagnosis (M66.829) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on synovial fluid crystal/cell in Biceps tendon rupture (M66.829: analysis when effused) alongside serial hs-CRP & Erythrocyte in Biceps tendon rupture (M66.829: Sedimentation Rate) tracking (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M66.829)) to guide individualized care.
Blood in joint (hemarthrosis)
Blood in joint (hemarthrosis) (also termed Hemarthrosis) is an ICD-10-CM indexed diagnosis (M25.00) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on serum urate/inflammatory marker in Blood in joint (hemarthrosis) (M25.00: profiling) alongside serial Weight-Bearing Joint Radiograph [Blood in joint (hemarthrosis) M25.00] tracking (Preserved joint-space width (M25.00)) to guide individualized care.
Blount's disease
Cataloged under federal diagnostic code M92.519 in Arthritis & Joints, Blount's disease requires urate-lowering titration [Blount's disease M92.519] so specialists can calibrate treatment intensity against Serum Uric Acid in Blount's disease (M92.519: (Gout Target)) benchmarks.
Bone disease - aluminum related
Within Osteoarthritis, Gout & Joint Pain practice, Bone disease - aluminum related (ICD-10 M83.4) is stratified through urate-lowering titration [Bone disease - aluminum related M83.4], pairing targeted symptom control with longitudinal Serum Uric Acid in Bone disease - aluminum related (M83.4: (Gout Target)) surveillance.
Bone pain
Cataloged under federal diagnostic code M89.8X9 in Arthritis & Joints, Bone pain (also termed Pain or Ache) requires urate-lowering titration [Bone pain M89.8X9] so specialists can calibrate treatment intensity against Weight-Bearing Joint Radiograph [Bone pain M89.8X9] benchmarks.
Bone spur (exostosis)
Within Osteoarthritis, Gout & Joint Pain practice, Bone spur (exostosis) (also termed Exostosis) (ICD-10 M89.9) is stratified through urate-lowering titration [Bone spur (exostosis) M89.9], pairing targeted symptom control with longitudinal Weight-Bearing Joint Radiograph [Bone spur (exostosis) M89.9] surveillance.
Bouchard's nodes (with arthropathy)
Recognized across U.S. clinical coding as M15.2 (Arthritis & Joints), Bouchard's nodes (with arthropathy) is evaluated via weight-bearing joint radiography [Bouchard's nodes (with arthropathy) M15.2] to align day-to-day symptom relief with long-term physiological stability.
Bunion
Bunion is an ICD-10-CM indexed diagnosis (M21.619) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on urate-lowering titration [Bunion M21.619] alongside serial Weight-Bearing Joint Radiograph [Bunion M21.619] tracking (Preserved joint-space width (M21.619)) to guide individualized care.
Bursitis
A bursa is a small, fluid-filled sac that acts as a cushion between a bone and other moving parts, such as muscles, tendons, or skin. Bursitis occurs when a bursa becomes inflamed. People get bursitis by overusing a joint. It can also be caused by an injury. It usually occurs at the knee or elbow. Kneeling or leaning your elbows on a hard surface for a long time can make bursitis start. Doing the same kinds of movements every day or putting stress on joints increases your risk. Symptoms of bursitis include pain and swelling. Your doctor will diagnose bursitis with a physical exam and tests such as x-rays and MRIs.
Capsulitis - adhesive
Within Osteoarthritis, Gout & Joint Pain practice, Capsulitis - adhesive (ICD-10 M77.9) is stratified through weight-bearing joint radiography [Capsulitis - adhesive M77.9], pairing targeted symptom control with longitudinal hs-CRP & Erythrocyte in Capsulitis - adhesive (M77.9: Sedimentation Rate) surveillance.
Cartilage Disorders
Cartilage is the tough but flexible tissue that covers the ends of your bones at a joint. It also gives shape and support to other parts of your body, such as your ears, nose and windpipe. Healthy cartilage helps you move by allowing your bones to glide over each other. It also protects bones by preventing them from rubbing against each other. Injured, inflamed, or damaged cartilage can cause symptoms such as pain and limited movement. It can also lead to joint damage and deformity.
Contracture
Physicians managing Contracture (M62.40; Osteoarthritis, Gout & Joint Pain) utilize urate-lowering titration [Contracture M62.40] and objective hs-CRP & Erythrocyte in Contracture (M62.40: Sedimentation Rate) targets (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M62.40)) to prevent progression and functional morbidity.
Costochondritis
Clinical triage of Costochondritis (M94.0) in Arthritis & Joints relies on weight-bearing joint radiography [Costochondritis M94.0], guiding step-wise therapeutic adjustments toward Weight-Bearing Joint Radiograph [Costochondritis M94.0] (Preserved joint-space width (M94.0)).
Craniofacial Abnormalities
Craniofacial is a medical term that relates to the bones of the skull and face. Craniofacial abnormalities are birth defects of the face or head. Some, like cleft lip and palate , are among the most common of all birth defects. Others are very rare. Most of them affect how a person's face or head looks. These conditions may also affect other parts of the body. Treatment depends on the type of problem. Plastic and reconstructive surgery may help the person's appearance.
Dermatomyositis
Clinical triage of Dermatomyositis (M33.90) in Arthritis & Joints relies on synovial fluid crystal/cell in Dermatomyositis (M33.90: analysis when effused), guiding step-wise therapeutic adjustments toward Weight-Bearing Joint Radiograph [Dermatomyositis M33.90] (Preserved joint-space width (M33.90)).
Diskitis
Diskitis (also termed Diskitis or Discitis)—coded clinically as M46.40 across Arthritis & Joints guidelines—combines urate-lowering titration [Diskitis M46.40] with structured follow-up of Serum Uric Acid in Diskitis (M46.40: (Gout Target)) (< 6.0 mg/dL (< 5.0 mg/dL with tophi) (M46.40)).
Dislocations
Dislocations are joint injuries that force the ends of your bones out of position. The cause is often a fall or a blow, sometimes from playing a contact sport . You can dislocate your ankles, knees, shoulders , hips, elbows and jaw. You can also dislocate your finger and toe joints. Dislocated joints often are swollen, very painful and visibly out of place. You may not be able to move it. A dislocated joint is an emergency. If you have one, seek medical attention. Treatment depends on which joint you dislocate and the severity of the injury. It might include manipulations to reposition your bones, medicine, a splint or sling, and rehabilitation.
Dwarfism
People with dwarfism have short stature. This means that their height is under 4' 10" as an adult. They are usually of normal intelligence. Dwarfism most often does happen in families where both parents are of average height. More than 300 different conditions can cause dwarfism. Achondroplasia is the most common type of dwarfism. Achondroplasia is a genetic condition that affects about 1 in 15,000 to 1 in 40,000 people. It makes your arms and legs short in comparison to your head and trunk. You may also have a larger head and weak muscle tone. Other genetic conditions, kidney disease, and problems with metabolism or hormones can also cause dwarfism.
Ehlers-Danlos Syndrome
Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that weaken connective tissues . Connective tissues are proteins that support skin, bones, blood vessels, and other organs. EDS usually affects your skin, joints and blood vessel walls. Symptoms include: Loose joints Fragile, small blood vessels Abnormal scar formation and wound healing Soft, velvety, stretchy skin that bruises easily There are several types of EDS. They can range from mild to life-threatening. About 1 in 5,000 people has EDS. There is no cure. Treatment involves managing symptoms, often with medicines and physical therapy.
Elbow Injuries and Disorders
Your elbow joint is made up of bone, cartilage, ligaments and fluid. Muscles and tendons help the elbow joint move. When any of these structures is hurt or diseased, you have elbow problems. Many things can make your elbow hurt. A common cause is tendinitis , an inflammation or injury to the tendons that attach muscle to bone. Tendinitis of the elbow is a sports injury , often from playing tennis or golf. You may also get tendinitis from overuse of the elbow. Other causes of elbow pain include sprains and strains , fractures (broken bones), dislocations , bursitis , and arthritis . Treatment depends on the cause.
Elbow pain
Designated in federal medical registries as M25.529, Elbow pain (also termed Pain or Ache) falls under Arthritis & Joints management, where synovial fluid crystal/cell in Elbow pain (M25.529: analysis when effused) establishes baseline severity and rules out diagnostic mimics.
Erosive (osteo)arthritis
Cataloged under federal diagnostic code M15.4 in Arthritis & Joints, Erosive (osteo)arthritis requires weight-bearing joint radiography [Erosive (osteo)arthritis M15.4] so specialists can calibrate treatment intensity against Serum Uric Acid in Erosive (osteo)arthritis (M15.4: (Gout Target)) benchmarks.
Familial Mediterranean fever
Familial Mediterranean fever (also termed Family or Familial)—coded clinically as M04.1 across Arthritis & Joints guidelines—combines serum urate/inflammatory marker in Familial Mediterranean fever (M04.1: profiling) with structured follow-up of Serum Uric Acid in Familial Mediterranean fever (M04.1: (Gout Target)) (< 6.0 mg/dL (< 5.0 mg/dL with tophi) (M04.1)).
Fasciitis - necrotizing
Fasciitis - necrotizing—coded clinically as M72.6 across Arthritis & Joints guidelines—combines weight-bearing joint radiography [Fasciitis - necrotizing M72.6] with structured follow-up of hs-CRP & Erythrocyte in Fasciitis - necrotizing (M72.6: Sedimentation Rate) (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M72.6)).
Fasciitis - nodular
Fasciitis - nodular (also termed Nodule or Nodular)—coded clinically as M72.4 across Arthritis & Joints guidelines—combines topical/targeted anti-inflammatory therapy [Fasciitis - nodular M72.4] with structured follow-up of hs-CRP & Erythrocyte in Fasciitis - nodular (M72.4: Sedimentation Rate) (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M72.4)).
Finger Injuries and Disorders
You use your fingers and thumbs to do everything from grasping objects to playing musical instruments to typing. When there is something wrong with them, it can make life difficult. Common problems include: Injuries that result in fractures (broken bones), ruptured ligaments and dislocations Osteoarthritis - wear-and-tear arthritis. It can also cause deformity. Tendinitis - irritation of the tendons Dupuytren's contracture - a hereditary thickening of the tough tissue that lies just below the skin of your palm. It causes the fingers to stiffen and bend. Trigger finger - an irritation of the sheath that surrounds the flexor tendons.
Fistula, unspecified joint
Recognized across U.S. clinical coding as M25.10 (Arthritis & Joints), Fistula, unspecified joint is evaluated via weight-bearing joint radiography [Fistula, unspecified joint M25.10] to align day-to-day symptom relief with long-term physiological stability.
Flat feet
Flat feet (also termed Planus or Flat)—coded clinically as M21.40 across Arthritis & Joints guidelines—combines topical/targeted anti-inflammatory therapy [Flat feet M21.40] with structured follow-up of Serum Uric Acid in Flat feet (M21.40: (Gout Target)) (< 6.0 mg/dL (< 5.0 mg/dL with tophi) (M21.40)).
Foot Health
Each step you take involves a complex network of bones, muscles, tendons, and ligaments. This, combined with all of the weight they carry, explains why feet can have problems. To keep your feet healthy: Examine your feet regularly Wear comfortable shoes that fit Wash your feet daily with soap and lukewarm water Trim your toenails straight across and not too short Your foot health can be a clue to your overall health. For example, joint stiffness could mean arthritis. Tingling or numbness could be a sign of diabetes. Swelling might indicate kidney disease, heart disease, or high blood pressure.
Foot drop
Within Osteoarthritis, Gout & Joint Pain practice, Foot drop (also termed Foot or Pedes) (ICD-10 M21.379) is stratified through topical/targeted anti-inflammatory therapy [Foot drop M21.379], pairing targeted symptom control with longitudinal Weight-Bearing Joint Radiograph [Foot drop M21.379] surveillance.
Goodpasture's syndrome
Recognized across U.S. clinical coding as M31.0 (Arthritis & Joints), Goodpasture's syndrome (also termed Disorder or Syndrome) is evaluated via weight-bearing joint radiography [Goodpasture's syndrome M31.0] to align day-to-day symptom relief with long-term physiological stability.
Gout
What is gout? Gout is a common type of inflammatory arthritis . It causes pain, swelling, and redness in one or more joints. It usually happens as a flare, which can last for a week or two and then gets better. The flares often begin in your big toe or a lower limb. What causes gout? Gout happens when too much uric acid (urate) builds up in your body over a long time. Uric acid is a waste product your body makes when it breaks down purines. Purines are substances that are in your body's tissues and in many foods. When your body breaks down old cells or digests foods that contain purine, most of the uric acid that's made dissolves in your blood.
Granuloma - necrotizing
Under Osteoarthritis, Gout & Joint Pain diagnostic criteria (M31.30), workup for Granuloma - necrotizing integrates urate-lowering titration [Granuloma - necrotizing M31.30] with evidence-graded therapy tailored to hs-CRP & Erythrocyte in Granuloma - necrotizing (M31.30: Sedimentation Rate) response.
Hammer toe
Within Osteoarthritis, Gout & Joint Pain practice, Hammer toe (also termed Toes or Dactyl) (ICD-10 M20.40) is stratified through urate-lowering titration [Hammer toe M20.40], pairing targeted symptom control with longitudinal Weight-Bearing Joint Radiograph [Hammer toe M20.40] surveillance.
Heberden's nodes (with arthropathy)
Under Osteoarthritis, Gout & Joint Pain diagnostic criteria (M15.1), workup for Heberden's nodes (with arthropathy) integrates serum urate/inflammatory marker in Heberden's nodes (with arthropathy) (M15.1: profiling) with evidence-graded therapy tailored to hs-CRP & Erythrocyte in Heberden's nodes (with arthropathy) (M15.1: Sedimentation Rate) response.
Heel Injuries and Disorders
Heel problems are common and can be painful. Often, they result from too much stress on your heel bone and the tissues that surround it. That stress can come from: Injuries Bruises that you get walking, running or jumping Wearing shoes that don't fit or aren't made well Being overweight These can lead to tendinitis, bursitis, and fasciitis, which are all types of inflammation of the tissues that surround your heel. Over time the stress can cause bone spurs and deformities. Certain diseases, such as rheumatoid arthritis and gout, can also lead to heel problems. Treatments for heel problems might include rest, medicines, exercises, taping, and special shoes.
Hemarthrosis, unspecified joint
Recognized across U.S. clinical coding as M25.00 (Arthritis & Joints), Hemarthrosis, unspecified joint is evaluated via synovial fluid crystal/cell in Hemarthrosis, unspecified joint (M25.00: analysis when effused) to align day-to-day symptom relief with long-term physiological stability.
Hip Injuries and Disorders
Your hip is the joint where your femur (thigh bone) meets your pelvis (hip bone). There are two main parts: a ball at the end of the femur, which fits in a socket in the pelvis. Your hip is known as a ball-and-socket joint. This is because you have a ball at the end of your femur, and it fits into a socket in your pelvis. This makes your hips very stable and allows for a wide range of motion. When they are healthy, it takes great force to hurt them. However, playing sports, running, overuse, or falling can sometimes lead to hip injuries such as: Strains Bursitis Dislocations Fractures (broken bones) Certain diseases also lead to hip injuries or problems.
Hip Replacement
Hip replacement is surgery for people with severe hip damage. The most common cause of damage is osteoarthritis . Osteoarthritis causes pain, swelling, and reduced motion in your joints. It can interfere with your daily activities. If other treatments such as physical therapy, pain medicines, and exercise haven't helped, hip replacement surgery might be an option for you. During a hip replacement operation, the surgeon removes damaged cartilage and bone from your hip joint and replaces them with new, man-made parts.
Hip pain
Under Osteoarthritis, Gout & Joint Pain diagnostic criteria (M25.559), workup for Hip pain (also termed Pain or Ache) integrates synovial fluid crystal/cell in Hip pain (M25.559: analysis when effused) with evidence-graded therapy tailored to hs-CRP & Erythrocyte in Hip pain (M25.559: Sedimentation Rate) response.
Idiopathic gout, multiple sites
For patients presenting with Idiopathic gout, multiple sites (ICD-10-CM M10.09), Osteoarthritis, Gout & Joint Pain protocols prioritize synovial fluid crystal/cell in Idiopathic gout, multiple sites (M10.09: analysis when effused) paired with baseline and interval hs-CRP & Erythrocyte in Idiopathic gout, multiple sites (M10.09: Sedimentation Rate) assessment.
Idiopathic gout, unspecified site
Idiopathic gout, unspecified site—coded clinically as M10.00 across Arthritis & Joints guidelines—combines weight-bearing joint radiography [Idiopathic gout, unspecified site M10.00] with structured follow-up of Weight-Bearing Joint Radiograph [Idiopathic gout, unspecified site M10.00] (Preserved joint-space width (M10.00)).
Idiopathic gout, vertebrae
Idiopathic gout, vertebrae is an ICD-10-CM indexed diagnosis (M10.08) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on topical/targeted anti-inflammatory therapy [Idiopathic gout, vertebrae M10.08] alongside serial hs-CRP & Erythrocyte in Idiopathic gout, vertebrae (M10.08: Sedimentation Rate) tracking (hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M10.08)) to guide individualized care.
Infectious Arthritis
Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Infectious arthritis is an infection in the joint. The infection comes from a bacterial, viral, or fungal infection that spreads from another part of the body. Symptoms of infectious arthritis include: Intense pain in the joint Joint redness and swelling Chills and fever Inability to move the area with the infected joint One type of infectious arthritis is reactive arthritis. The reaction is to an infection somewhere else in your body. The joint is usually the knee, ankle, or toe.
Joint Disorders
What are joints? Your joints are places where two or more bones come together. Your shoulders, elbows, hips, knees, and knuckles are all joints. Your spine has joints, too. But joints are more than bones. They include the soft tissues around them, such as cartilage, tendons and ligaments. Cartilage is the hard slippery flexible tissue that covers the ends of your bones at a joint. Tendons are tough, flexible bands that connect your muscles to your bones so you can move your joints. Ligaments connect the bones of the joint to each other to keep them stable when you move. What are joint disorders? Joint disorders are diseases or injuries that affect your joints.
Joint contracture
Cataloged under federal diagnostic code M24.50 in Arthritis & Joints, Joint contracture (also termed Temporomandibular or Temporal) requires synovial fluid crystal/cell in Joint contracture (M24.50: analysis when effused) so specialists can calibrate treatment intensity against hs-CRP & Erythrocyte in Joint contracture (M24.50: Sedimentation Rate) benchmarks.
Joint pain (arthralgia)
Cataloged under federal diagnostic code M25.50 in Arthritis & Joints, Joint pain (arthralgia) (also termed Arthralgia) requires urate-lowering titration [Joint pain (arthralgia) M25.50] so specialists can calibrate treatment intensity against Weight-Bearing Joint Radiograph [Joint pain (arthralgia) M25.50] benchmarks.
Joint prosthesis
Within Osteoarthritis, Gout & Joint Pain practice, Joint prosthesis (also termed Temporomandibular or Temporal) (ICD-10 T84.9XXA) is stratified through weight-bearing joint radiography [Joint prosthesis T84.9XXA], pairing targeted symptom control with longitudinal hs-CRP & Erythrocyte in Joint prosthesis (T84.9XXA: Sedimentation Rate) surveillance.
Juvenile Arthritis
What is juvenile arthritis? Juvenile arthritis (JA) is arthritis that happens in children. It causes joint inflammation (swelling), pain, stiffness, and loss of motion. Joints are places where two bones meet, such as your elbow or knee. It can affect any joint, but it is more common in the knees, hands, and feet. JA can affect your child's growth and development, and in some cases, it can also affect other organs. Finding JA early and starting treatment can help manage symptoms and reduce joint damage. Who is more likely to get juvenile arthritis? There are several other forms of arthritis affecting children.
Juvenile rheumatoid arthritis (JRA)
Within Osteoarthritis, Gout & Joint Pain practice, Juvenile rheumatoid arthritis (JRA) (also termed Juvenile rheumatoid arthritis or Arthritic) (ICD-10 M08.80) is stratified through weight-bearing joint radiography [Juvenile rheumatoid arthritis (JRA) M08.80], pairing targeted symptom control with longitudinal Serum Uric Acid in Juvenile rheumatoid arthritis (JRA) (M08.80: (Gout Target)) surveillance.
Knee Replacement
What is knee replacement surgery? Knee replacement surgery is a surgery to replace parts of your knee joint with new, artificial parts. You may need a knee replacement if you have knee damage that causes severe pain and difficulty doing daily activities, such as walking and climbing stairs. It is usually done when other treatments for knee pain haven't helped enough. The goal of a knee replacement is to relieve pain and help you move better. People of all ages may have knee replacement surgery. But it is more common in older people. The decision whether to have surgery is based on your overall health and how much your knee bothers you.
Knee pain
For patients presenting with Knee pain (also termed Pain or Ache) (ICD-10-CM M25.569), Osteoarthritis, Gout & Joint Pain protocols prioritize synovial fluid crystal/cell in Knee pain (M25.569: analysis when effused) paired with baseline and interval Serum Uric Acid in Knee pain (M25.569: (Gout Target)) assessment.
Knock knee
Recognized across U.S. clinical coding as M21.069 (Arthritis & Joints), Knock knee is evaluated via topical/targeted anti-inflammatory therapy [Knock knee M21.069] to align day-to-day symptom relief with long-term physiological stability.
Kyphosis
Kyphosis—coded clinically as M40.209 across Arthritis & Joints guidelines—combines weight-bearing joint radiography [Kyphosis M40.209] with structured follow-up of Weight-Bearing Joint Radiograph [Kyphosis M40.209] (Preserved joint-space width (M40.209)).
Lead-induced gout, unspecified site
Clinical triage of Lead-induced gout, unspecified site (M10.10) in Arthritis & Joints relies on serum urate/inflammatory marker in Lead-induced gout, unspecified site (M10.10: profiling), guiding step-wise therapeutic adjustments toward Serum Uric Acid in Lead-induced gout, unspecified site (M10.10: (Gout Target)) (< 6.0 mg/dL (< 5.0 mg/dL with tophi) (M10.10)).
Leg Injuries and Disorders
Your legs are made up of bones, blood vessels, muscles, and other connective tissue. They are important for motion and standing. Playing sports, running, falling, or having an accident can damage your legs. Common leg injuries include sprains and strains , joint dislocations , and fractures (broken bones). These injuries can affect the entire leg, or just the foot , ankle , knee , or hip . Certain diseases also lead to leg problems. For example, knee osteoarthritis, common in older people, can cause pain and limited motion. Problems in your veins in your legs can lead to varicose veins or deep vein thrombosis .