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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M25.559

Hip pain

Also known as: Pain, Ache, Hurt, Cramp

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M25.559 • 8 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hip pain Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Hip pain?

Under Osteoarthritis, Gout & Joint Pain diagnostic criteria (M25.559), workup for Hip pain (also termed Pain or Ache) integrates synovial fluid crystal/cell in Hip pain (M25.559: analysis when effused) with evidence-graded therapy tailored to hs-CRP & Erythrocyte in Hip pain (M25.559: Sedimentation Rate) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Hip pain (ICD-10 M25.559) is driven by low-grade synovial metalloproteinase in Hip pain (M25.559: release); specialists in Osteoarthritis, Gout & Joint Pain monitor Weight-Bearing Joint Radiograph [Hip pain M25.559] to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Hip pain (M25.559): activity-related deep aching in Hip pain (M25.559: joint pain in)
  • • Secondary Hip pain clinical sign: brief morning joint in Hip pain (M25.559: stiffness)
  • • Symptom flares in Hip pain correlating with hs-CRP & Erythrocyte in Hip pain (M25.559: Sedimentation Rate) deviation outside hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M25.559)
  • • Functional arthritis & joints impact requiring synovial fluid crystal/cell in Hip pain (M25.559: analysis when effused) evaluation (M25.559)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Hip pain Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M25.559 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Hip pain (M25.559: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M25.559) Clinical Reference Target Range
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Hip pain M25.559] Preserved joint-space width (M25.559) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Uric Acid in Hip pain (M25.559: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M25.559) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Hip pain

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Treatment selection for Hip pain depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hip pain)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Postoperative Pain Treatment After Pancreatic: What a 1,468-Participant Study Found

The available evidence was insufficient to establish the superiority of any single pain-relieving strategy after major pancreatic surgery.

European journal of pain (London, England) • 2026-11-15 • Meta-Analysis
N = 1,468 99/100 PMID 42944586 ↗
New Insights on Pain Reduction in Linzagolix-Treated Patients With Uterine Fibroids: A Secondary: What a 1,012-Participant Study Found

This analysis showed that reductions in pain were significantly mediated by reductions in HMB (all doses) and FV (200 mg alone) in linzagolix-treated women with UFs.

BJOG : an international journal of obstetrics and gynaecology • 2025-08-15 • Phase III Randomized Trial
N = 1,012 96/100 PMID 40326221 ↗
New Insights on Exercise Type and Duration on Pain, Function, and Quality of Life in Patients: What a 3,808-Participant Study Found

J Orthop Sports Phys Ther 2026;56(11):724-734.

The Journal of orthopaedic and sports physical therapy • 2026-11-15 • Meta-Analysis
N = 3,808 94/100 PMID 42966901 ↗
New Insights on Efficacy of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute: What a 344-Participant Study Found

This pooled analysis reinforces the efficacy profile of CTC versus tramadol and, given that CTC permits lower daily tramadol dosing and thereby reduces unnecessary opioid use, this highlights its improved benefit/risk profile...

Drugs in R&D • 2024-06-15 • Phase III Randomized Trial
N = 344 93/100 PMID 38874739 ↗
New Insights on Clobetasol Propionate Ophthalmic Suspension to Treat Ocular Inflammation and Pain: What a 366-Participant Study Found

CPN 0.05% twice daily for 14 days was safe and rapidly improved inflammation, OP, and visual acuity after cataract surgery.

Ophthalmology • 2026-08-15 • Phase III Randomized Trial
N = 366 93/100 PMID 42097332 ↗
Zero-PHI Patient Support & Cohort Discussions

Hip pain Patient Community & “People Like Me” Threads

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