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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M25.00

Hemarthrosis, unspecified joint

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M25.00 • 6 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hemarthrosis, unspecified joint Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Hemarthrosis, unspecified joint?

Recognized across U.S. clinical coding as M25.00 (Arthritis & Joints), Hemarthrosis, unspecified joint is evaluated via synovial fluid crystal/cell in Hemarthrosis, unspecified joint (M25.00: analysis when effused) to align day-to-day symptom relief with long-term physiological stability.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in arthritis & joints, Hemarthrosis, unspecified joint (M25.00) involves monosodium urate or in Hemarthrosis, unspecified joint (M25.00: calcium pyrophosphate crystal). progression correlates with shifts in Weight-Bearing Joint Radiograph [Hemarthrosis, unspecified joint M25.00] (Preserved joint-space width (M25.00)).

Common Symptoms & Clinical Signs

  • • Presentation of Hemarthrosis, unspecified joint (M25.00): brief morning joint in Hemarthrosis, unspecified joint (M25.00: stiffness)
  • • Secondary Hemarthrosis, unspecified joint clinical sign: sudden, intensely painful, in Hemarthrosis, unspecified joint (M25.00: red swollen big-toe)
  • • Symptom flares in Hemarthrosis, unspecified joint correlating with Weight-Bearing Joint Radiograph [Hemarthrosis, unspecified joint M25.00] deviation outside Preserved joint-space width (M25.00)
  • • Functional arthritis & joints impact requiring synovial fluid crystal/cell in Hemarthrosis, unspecified joint (M25.00: analysis when effused) evaluation (M25.00)

Hemarthrosis, unspecified joint Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M25.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NLM Clinical Tables
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Hemarthrosis, unspecified joint M25.00] Preserved joint-space width (M25.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Uric Acid in Hemarthrosis, unspecified joint (M25.00: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M25.00) Clinical Reference Target Range
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Hemarthrosis, unspecified joint (M25.00: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M25.00) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Hemarthrosis, unspecified joint

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hemarthrosis, unspecified joint)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on A Phase 3, 56-week, randomised, gold-standard blind, compared against a dummy: What a 513-Participant Study Found

513 patients were randomised.

Clinical and experimental rheumatology • 2025-05-15 • Phase III Randomized Trial
N = 513 93/100 PMID 39808286 ↗
New Insights on Benefits and safety of risankizumab for active psoriatic arthritis: 24-week: What a 444-Participant Study Found

Treatment with risankizumab resulted in significant improvements versus placebo in key disease outcomes and was well tolerated in patients with PsA who were Bio-IR and/or csDMARD-IR.

Annals of the rheumatic diseases • 2022-03-15 • Phase III Randomized Trial
N = 444 93/100 PMID 34815219 ↗
Can This Approach Help? Inside the Latest Research on Real-world benefits and safety of LBAL, a candidate adalimumab biosimilar, and

LBAL was equivalent in efficacy and comparable in safety, including immunogenicity, to ADL.

Clinical and experimental rheumatology • 2022-05-15 • Phase III Randomized Trial
N = 191 88/100 PMID 34251303 ↗
Can This Approach Help? Inside the Latest Research on Efficacy, how the body absorbs the medicine and safety of subcutaneous versus

CT-P13 s.c.

Rheumatology (Oxford, England) • 2021-05-14 • Phase III Randomized Trial
N = 167 88/100 PMID 33230526 ↗
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