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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M25.00

Blood in joint (hemarthrosis)

Also known as: Hemarthrosis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M25.00 • 8 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Blood in joint (hemarthrosis) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Blood in joint (hemarthrosis)?

Blood in joint (hemarthrosis) (also termed Hemarthrosis) is an ICD-10-CM indexed diagnosis (M25.00) within Osteoarthritis, Gout & Joint Pain. Clinical evaluation centers on serum urate/inflammatory marker in Blood in joint (hemarthrosis) (M25.00: profiling) alongside serial Weight-Bearing Joint Radiograph [Blood in joint (hemarthrosis) M25.00] tracking (Preserved joint-space width (M25.00)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Blood in joint (hemarthrosis) (M25.00) features subchondral bone remodeling [Blood in joint (hemarthrosis) M25.00]. therapeutic stabilization in arthritis & joints is verified against Serum Uric Acid in Blood in joint (hemarthrosis) (M25.00: (Gout Target)).

Common Symptoms & Clinical Signs

  • • Presentation of Blood in joint (hemarthrosis) (M25.00): activity-related deep aching in Blood in joint (hemarthrosis) (M25.00: joint pain in)
  • • Secondary Blood in joint (hemarthrosis) clinical sign: brief morning joint in Blood in joint (hemarthrosis) (M25.00: stiffness)
  • • Symptom flares in Blood in joint (hemarthrosis) correlating with Weight-Bearing Joint Radiograph [Blood in joint (hemarthrosis) M25.00] deviation outside Preserved joint-space width (M25.00)
  • • Functional arthritis & joints impact requiring serum urate/inflammatory marker in Blood in joint (hemarthrosis) (M25.00: profiling) evaluation (M25.00)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Blood in joint (hemarthrosis) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M25.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Blood in joint (hemarthrosis) M25.00] Preserved joint-space width (M25.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Uric Acid in Blood in joint (hemarthrosis) (M25.00: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M25.00) Clinical Reference Target Range
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Blood in joint (hemarthrosis) (M25.00: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M25.00) Clinical Reference Target Range
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Treatment selection for Blood in joint (hemarthrosis) depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Blood in joint (hemarthrosis))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Achieved blood pressure and heart and blood vessel outcomes in high-risk: What a 8,407-Participant Study Found

Mean achieved SBP less than 120 mm Hg during treatment was associated with increased risk of heart and blood vessel outcomes except for heart attack and stroke.

Lancet (London, England) • 2017-06-03 • Meta-Analysis
N = 8,407 99/100 PMID 28390695 ↗
New Insights on Telmisartan and amlodipine single-pill combinations vs amlodipine single-drug: What a 1,097-Participant Study Found

Superior BP reductions were also seen with T40-T80/A5 vs A10, with BP goal rates at least as high as with A10; however, there was significantly more peripheral edema with A10 (27.2% vs 4.3% for pooled.

Journal of clinical hypertension (Greenwich, Conn.) • 2011-07-15 • Randomized Controlled Trial
N = 1,097 96/100 PMID 21762357 ↗
Check Your Medicine Cabinet: Early Alert: B. Braun Removes Streamline Bloodline Set for Dialog+

The dialyzer connector may not be attached appropriately, resulting in leaking and potential blood loss.

FDA MedWatch Safety Alerts • 2026-10-27 • FDA Safety Alert
Multi-cohort 95/100 PMID FDA_MEDWATCH-112457955 ↗
Randomized trials of telmisartan vs. Losartan: Which Works Better for Reduction of ambulatory blood pressure?

Pooled analysis suggested significant reductions in all of 24-h (MD of systolic/diastolic BP, -2.09/-1.57 mm Hg; 95% CI, -3.39/-2.32 to -0.79/-0.82 mm Hg), last 6-h (-2.96/-2.15 mm Hg; -3.80/-2.72 to -2.13/-1.59 mm Hg),...

Hypertension research : official journal of the Japanese Society of Hypertension • 2013-11-15 • Meta-Analysis
N = 2,409 94/100 PMID 23945962 ↗
Randomized trials of telmisartan vs. Valsartan therapy: Which Works Better for Blood pressure reduction?

When data from the single-drug treatment and combination therapy (with hydrochlorothiazide) trials were pooled separately, telmisartan therapy was associated with a statistically significant difference in BP reductions...

Hypertension research : official journal of the Japanese Society of Hypertension • 2013-07-15 • Meta-Analysis
N = 5,422 94/100 PMID 23344134 ↗
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