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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M10.00

Idiopathic gout, unspecified site

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M10.00 • 7 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Idiopathic gout, unspecified site Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Idiopathic gout, unspecified site?

Idiopathic gout, unspecified site—coded clinically as M10.00 across Arthritis & Joints guidelines—combines weight-bearing joint radiography [Idiopathic gout, unspecified site M10.00] with structured follow-up of Weight-Bearing Joint Radiograph [Idiopathic gout, unspecified site M10.00] (Preserved joint-space width (M10.00)).

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Idiopathic gout, unspecified site (M10.00) center on monosodium urate or in Idiopathic gout, unspecified site (M10.00: calcium pyrophosphate crystal). targeted arthritis & joints interventions aim to normalize hs-CRP & Erythrocyte in Idiopathic gout, unspecified site (M10.00: Sedimentation Rate).

Common Symptoms & Clinical Signs

  • • Presentation of Idiopathic gout, unspecified site (M10.00): brief morning joint in Idiopathic gout, unspecified site (M10.00: stiffness)
  • • Secondary Idiopathic gout, unspecified site clinical sign: sudden, intensely painful, in Idiopathic gout, unspecified site (M10.00: red swollen big-toe)
  • • Symptom flares in Idiopathic gout, unspecified site correlating with hs-CRP & Erythrocyte in Idiopathic gout, unspecified site (M10.00: Sedimentation Rate) deviation outside hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M10.00)
  • • Functional arthritis & joints impact requiring weight-bearing joint radiography [Idiopathic gout, unspecified site M10.00] evaluation (M10.00)

Idiopathic gout, unspecified site Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M10.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NLM Clinical Tables
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Idiopathic gout, unspecified site (M10.00: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M10.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Idiopathic gout, unspecified site M10.00] Preserved joint-space width (M10.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Uric Acid in Idiopathic gout, unspecified site (M10.00: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M10.00) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Idiopathic gout, unspecified site)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Influence of Demographic Factors on Clinical Outcomes in Adults With Chronic: What a 2,639-Participant Study Found

Overall (N = 2,639; 3 mg of plecanatide [n = 877]; 6 mg of plecanatide [n = 877]; and placebo [n = 885]), CSBM responder rates were significantly greater with 3 mg of plecanatide and 6 mg of plecanatide vs placebo in subgroups...

Clinical and translational gastroenterology • 2023-07-01 • Phase III Randomized Trial
N = 2,639 96/100 PMID 37162147 ↗
New Insights on Apremilast single-drug treatment for long-term treatment of active psoriatic: What a 527-Participant Study Found

Apremilast led to sustained PsA efficacy up to 260 weeks and was well tolerated.

Rheumatology (Oxford, England) • 2022-03-02 • Phase III Randomized Trial
N = 527 93/100 PMID 34100922 ↗
New Insights on Serum biomarkers associated with baricitinib response in patients with juvenile: What a 220-Participant Study Found

To our knowledge, this is the first study measuring serum protein markers in the context of an intervention trial with baricitinib in patients with JIA.

The Lancet. Rheumatology • 2025-11-15 • Phase III Randomized Trial
N = 220 88/100 PMID 40915298 ↗
Can This Approach Help? Inside the Latest Research on Benefits of finasteride for hirsute women with polycystic ovary syndrome or

All the patients treated with finasteride perceived a reduction in hirsutism after 6 months.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2003-02-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 12724020 ↗
Can This Approach Help? Inside the Latest Research on Low-sodium oxybate on diary-based sleep time in a clinical study in adults with

Open-label LXB treatment in adults with idiopathic hypersomnia was associated with reductions in 24-hour TST, nocturnal TST, and total nap duration.

Sleep medicine • 2026-02-15 • Phase III Randomized Trial
N = 148 88/100 PMID 41442817 ↗
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