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Cancer, Oncology & Supportive Care • ICD-10-CM C34.9

Bile Duct Cancer

Also known as: Cholangiocarcinoma

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C34.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Bile Duct Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Bile Duct Cancer?

Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts . They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes. Bile duct cancer is rare. It can happen in the parts of the bile ducts that are outside or inside the liver. Cancer of the bile duct outside of the liver is much more common. Risk factors include having inflammation of the bile duct, ulcerative colitis , and some liver diseases.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Bile Duct Cancer (ICD-10 C34.9) is driven by somatic oncogenic driver in Bile Duct Cancer (C34.9: mutations); Cross-referenced with NIH MeSH (Bile Duct Neoplasms), specialists in Cancer, Oncology & Supportive Care monitor Comprehensive Metabolic & in Bile Duct Cancer (C34.9: Organ Function Panel) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Bile Duct Cancer (C34.9): abnormality detected early in Bile Duct Cancer (C34.9: on age-appropriate screening)
  • • Secondary Bile Duct Cancer clinical sign: persistent painless lump, in Bile Duct Cancer (C34.9: non-healing ulcer/mole change,)
  • • Symptom flares in Bile Duct Cancer correlating with Complete Blood Count in Bile Duct Cancer (C34.9: (ANC, Hemoglobin, Platelets)) deviation outside Safe hematologic reserve (C34.9)
  • • Functional cancer & oncology impact requiring targeted/immunotherapy [Bile Duct Cancer C34.9] evaluation (C34.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Bile Duct Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C34.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in Bile Duct Cancer (C34.9: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C34.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Bile Duct Cancer (C34.9: Organ Function Panel) Preserved renal/hepatic clearance (C34.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Bile Duct Cancer (C34.9: Genomic Staging) Guideline-concordant surveillance (C34.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Bile Duct Cancer

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Treatment selection for Bile Duct Cancer depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Bile Duct Cancer)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Improved Pain, Morning Stiffness, and Fatigue With Bimekizumab in Axial

Bimekizumab treatment led to rapid improvements in levels of pain and morning stiffness.

The Journal of rheumatology • 2025-01-01 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 39406403 ↗
Can This Approach Help? Inside the Latest Research on Bimekizumab efficacy in male and female patients with axial spondyloarthritis:

Although male patients had earlier clinical responses to bimekizumab treatment, female patients demonstrated longer-term improvements in composite and patient-reported outcomes.

Rheumatology (Oxford, England) • 2026-10-01 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 42605056 ↗
Can This Approach Help? Inside the Latest Research on Evaluating the Efficacy of MamaLift Plus Digital Therapeutic Mobile App for

Participants who received MamaLift Plus exhibited significant and clinically meaningful improvement in depressive symptoms compared with control.

Journal of medical Internet research • 2025-07-01 • Phase III Randomized Trial
N = 95 88/100 PMID 40549508 ↗
New Insights on Association of mobile application information on multidisciplinary therapy and: What a 508-Participant Study Found

The RJBC-APP did not improve 12-month add-on treatment compliance rate for early-stage breast cancer patients receiving MDT.

Breast (Edinburgh, Scotland) • 2026-08-15 • Phase III Randomized Trial
N = 508 87/100 PMID 42150214 ↗
Can This Approach Help? Inside the Latest Research on A phase III randomized controlled trial comparing local field with additional

We plan to enroll 280 patients from 54 institutions over 4 years.

Japanese journal of clinical oncology • 2024-01-07 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 37801434 ↗
Zero-PHI Patient Support & Cohort Discussions

Bile Duct Cancer Patient Community & “People Like Me” Threads

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