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High Blood Pressure & Vascular Health • ICD-10-CM I82.9

Blood Pressure Medicines

Also known as: Antihypertensive medicines, High blood pressure medicines

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I82.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Blood Pressure Medicines Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Blood Pressure Medicines?

What is high blood pressure? High blood pressure , also called hypertension, is when blood puts too much pressure against the walls of your arteries. Almost half of American adults have high blood pressure, usually with no symptoms. But it can cause serious problems such as stroke , heart failure , heart attack , and kidney disease .

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Blood Pressure Medicines (I82.9) center on renin-angiotensin-aldosterone system upregulation [Blood Pressure Medicines I82.9]. Cross-referenced with NIH MeSH (Antihypertensive Agents), targeted blood pressure interventions aim to normalize Serum Creatinine & in Blood Pressure Medicines (I82.9: Potassium).

Common Symptoms & Clinical Signs

  • • Being physically active
  • • Reducing sodium in your diet
  • • Presentation of Blood Pressure Medicines (I82.9): morning occipital headache, in Blood Pressure Medicines (I82.9: pulsatile tinnitus, or)
  • • Secondary Blood Pressure Medicines clinical sign: calf cramping or in Blood Pressure Medicines (I82.9: claudication triggered by)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Blood Pressure Medicines Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I82.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub High Blood Pressure & Vascular Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Serum Creatinine & in Blood Pressure Medicines (I82.9: Potassium) K+ 4.0 – 4.8 mEq/L (I82.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio [Blood Pressure Medicines I82.9] < 15 mg/g (I82.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Home Seated Blood in Blood Pressure Medicines (I82.9: Pressure) < 120/75 mmHg (I82.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Blood Pressure Medicines

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Brukinsa (Zanubrutinib) Brukinsa • RxCUI RXN-B72579122 Kinase Inhibitor 83% $0.9900 $ 79.78 /mo
Avapritinib Ayvakit • RxCUI RXN-72064110-2593 Kinase Inhibitor 88% $3.3100 $ 142.56 /mo
Sudafed Sinus 12 Hour Pressure Plus Pain (Naproxen Sodium and Pseudoephedrine Hydrochloride) Sudafed Sinus 12 Hour Pressure Plus Pain • RxCUI 1367426 Nonsteroidal Anti-inflammatory Drug 80% $0.1442 $ 18.88 /mo
Timolol Betimol, Timoptic • RxCUI 208560 beta-Adrenergic Blocker 74% $31.0625 $ 6.97 /mo
Latanoprost Ophthalmic Solution 0.005% Iyuzeh • RxCUI 314072 Prostaglandin Analog 75% $10.1187 $ 185.00 /mo
Zanubrutinib Brukinsa • RxCUI RXN-72579122-2253 Kinase Inhibitor 80% $3.2000 $ 138.10 /mo
Latanoprostene Bunod Vyzulta • RxCUI 1988394 FDA Prescription Therapeutic Agent 78% $99.2842 $ 185.00 /mo
Brinzolamide Azopt • RxCUI 213272 Carbonic Anhydrase Inhibitor 93% $35.0627 $ 62.50 /mo
Tevimbra (Tislelizumab-Jsgr) Tevimbra • RxCUI RXN-B72579121 Programmed Death Receptor-1 Blocking Antibody 84% $3.0600 $ 228.82 /mo
Travoprost Travatan Z • RxCUI 284008 Prostaglandin Analog 93% $94.1791 $ 15.22 /mo
Brimonidine Tartrate Alphagan P, Lumify Preservative Free Eye Drops • RxCUI 861204 alpha-Adrenergic Agonist 92% $8.1556 $ 9.60 /mo
Mylanta Gas Minis Assorted Fruit Flavor (Simethicone) Mylanta Gas Minis Assorted Fruit Flavor • RxCUI 314221 Skin Barrier Activity 83% $0.0473 $ 11.90 /mo
Norepinephrine Bitartrate Levophed • RxCUI 242969 Catecholamine 76% $2.1200 $ 94.36 /mo
Brimonidine Tartrate and Timolol Maleate Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution, Brimonidine Tartrate/Timolol Maleate • RxCUI 861635 alpha-Adrenergic Agonist 92% $1.8390 $ 82.98 /mo
Timolol Maleate Timoptic, Timolol Gfs • RxCUI 1923428 beta-Adrenergic Blocker 82% $1.0344 $ 6.97 /mo
Dorzolamide Hydrochloride Timolol Maleate Cosopt • RxCUI 1923432 Carbonic Anhydrase Inhibitor 93% $0.8853 $ 10.75 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Blood Pressure Medicines)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Achieved blood pressure and heart and blood vessel outcomes in high-risk: What a 8,407-Participant Study Found

Mean achieved SBP less than 120 mm Hg during treatment was associated with increased risk of heart and blood vessel outcomes except for heart attack and stroke.

Lancet (London, England) • 2017-06-03 • Meta-Analysis
N = 8,407 99/100 PMID 28390695 ↗
New Insights on Telmisartan and amlodipine single-pill combinations vs amlodipine single-drug: What a 1,097-Participant Study Found

Superior BP reductions were also seen with T40-T80/A5 vs A10, with BP goal rates at least as high as with A10; however, there was significantly more peripheral edema with A10 (27.2% vs 4.3% for pooled.

Journal of clinical hypertension (Greenwich, Conn.) • 2011-07-15 • Randomized Controlled Trial
N = 1,097 96/100 PMID 21762357 ↗
Check Your Medicine Cabinet: Early Alert: B. Braun Removes Streamline Bloodline Set for Dialog+

The dialyzer connector may not be attached appropriately, resulting in leaking and potential blood loss.

FDA MedWatch Safety Alerts • 2026-10-27 • FDA Safety Alert
Multi-cohort 95/100 PMID FDA_MEDWATCH-112457955 ↗
Randomized trials of telmisartan vs. Losartan: Which Works Better for Reduction of ambulatory blood pressure?

Pooled analysis suggested significant reductions in all of 24-h (MD of systolic/diastolic BP, -2.09/-1.57 mm Hg; 95% CI, -3.39/-2.32 to -0.79/-0.82 mm Hg), last 6-h (-2.96/-2.15 mm Hg; -3.80/-2.72 to -2.13/-1.59 mm Hg),...

Hypertension research : official journal of the Japanese Society of Hypertension • 2013-11-15 • Meta-Analysis
N = 2,409 94/100 PMID 23945962 ↗
Randomized trials of telmisartan vs. Valsartan therapy: Which Works Better for Blood pressure reduction?

When data from the single-drug treatment and combination therapy (with hydrochlorothiazide) trials were pooled separately, telmisartan therapy was associated with a statistically significant difference in BP reductions...

Hypertension research : official journal of the Japanese Society of Hypertension • 2013-07-15 • Meta-Analysis
N = 5,422 94/100 PMID 23344134 ↗
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Blood Pressure Medicines Patient Community & “People Like Me” Threads

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