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High Blood Pressure & Vascular Health • ICD-10-CM I11.9

Cardiovascular disease - hypertensive

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I11.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Cardiovascular disease - hypertensive Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Cardiovascular disease - hypertensive?

Cardiovascular disease - hypertensive is an ICD-10-CM indexed diagnosis (I11.9) within High Blood Pressure & Vascular Health. Clinical evaluation centers on duplex vascular ultrasonography [Cardiovascular disease - hypertensive I11.9] alongside serial Serum Creatinine & in Cardiovascular disease - hypertensive (I11.9: Potassium) tracking (K+ 4.0 – 4.8 mEq/L (I11.9)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

In Cardiovascular disease - hypertensive (I11.9), physiological disruption stems from renin-angiotensin-aldosterone system upregulation [Cardiovascular disease - hypertensive I11.9], informing High Blood Pressure & Vascular Health protocols that track Urine Albumin-to-Creatinine Ratio [Cardiovascular disease - hypertensive I11.9] (< 15 mg/g (I11.9)).

Common Symptoms & Clinical Signs

  • • Presentation of Cardiovascular disease - hypertensive (I11.9): persistently elevated home in Cardiovascular disease - hypertensive (I11.9: or clinic blood)
  • • Secondary Cardiovascular disease - hypertensive clinical sign: morning occipital headache, in Cardiovascular disease - hypertensive (I11.9: pulsatile tinnitus, or)
  • • Symptom flares in Cardiovascular disease - hypertensive correlating with Serum Creatinine & in Cardiovascular disease - hypertensive (I11.9: Potassium) deviation outside K+ 4.0 – 4.8 mEq/L (I11.9)
  • • Functional blood pressure impact requiring duplex vascular ultrasonography [Cardiovascular disease - hypertensive I11.9] evaluation (I11.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Cardiovascular disease - hypertensive Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I11.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub High Blood Pressure & Vascular Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Serum Creatinine & in Cardiovascular disease - hypertensive (I11.9: Potassium) K+ 4.0 – 4.8 mEq/L (I11.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio [Cardiovascular disease - hypertensive I11.9] < 15 mg/g (I11.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Home Seated Blood in Cardiovascular disease - hypertensive (I11.9: Pressure) < 120/75 mmHg (I11.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Cardiovascular disease - hypertensive

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Sotagliflozin Inpefa • RxCUI 2638683 Sodium-Glucose Cotransporter 2 Inhibitor 94% $20.3408 $ 185.00 /mo
Entresto (Sacubitril and Valsartan) Entresto • RxCUI 1656351 Angiotensin 2 Receptor Blocker 94% $11.6248 $ 6.98 /mo
Sacubitril and Valsartan Entresto • RxCUI 1656349 Angiotensin 2 Receptor Blocker 91% $0.5265 $ 29.82 /mo
Ticagrelor Brilinta • RxCUI 1116635 P2Y12 Platelet Inhibitor 81% $0.2429 $ 10.64 /mo
Prasugrel Effient • RxCUI 855812 P2Y12 Platelet Inhibitor 79% $0.2893 $ 8.50 /mo
Alirocumab Praluent • RxCUI 1659156 PCSK9 Inhibitor 86% $250.5510 $ 185.00 /mo
Tirofiban Aggrastat • RxCUI 1737466 Platelet Aggregation Inhibitor 87% $2.9000 $ 125.95 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Cardiovascular disease - hypertensive)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Achieved blood pressure and heart and blood vessel outcomes in high-risk: What a 8,407-Participant Study Found

Mean achieved SBP less than 120 mm Hg during treatment was associated with increased risk of heart and blood vessel outcomes except for heart attack and stroke.

Lancet (London, England) • 2017-06-03 • Meta-Analysis
N = 8,407 99/100 PMID 28390695 ↗
New Insights on Effect of Glucagon-like Peptide-1 Receptor Agonists on All-cause Mortality and: What a 21,135-Participant Study Found

GLP1RA therapy when compared to placebo reduced all-cause mortality in high heart and blood vessel risk patients with type 2 diabetes.

Current diabetes reviews • 2018-01-15 • Meta-Analysis
N = 21,135 99/100 PMID 28413990 ↗
New Insights on Heart and blood vessel outcomes of liraglutide in patients with type 2: What a 14,608-Participant Study Found

Our results suggest that liraglutide treatment decreases the risk of MACE, AMI, all-cause death and heart and blood vessel death among patients with type 2 diabetes.

Medicine • 2019-11-15 • Meta-Analysis
N = 14,608 99/100 PMID 31725627 ↗
New Insights on Association between testosterone replacement therapy and heart and blood vessel: What a 11,502-Participant Study Found

Our analysis indicates that for patients with hypogonadism, testosterone replacement therapy does not increase the CVD risk and all-cause mortality.

Progress in cardiovascular diseases • 2024-01-15 • Meta-Analysis
N = 11,502 99/100 PMID 38589271 ↗
New Insights on Heart and blood vessel and Kidney Outcomes and Mortality With Long-Acting: What a 71,351-Participant Study Found

As a group, long-acting GLP-1RA, including both injectable and oral formulations, reduce incidence of MACE, HHF, and kidney events and all-cause mortality in T2D.

Diabetes care • 2025-05-01 • Meta-Analysis
N = 71,351 99/100 PMID 40156846 ↗
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