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Bacterial, Viral & Fungal Infections • ICD-10-CM L03.90

Cellulitis

Also known as: Carpus, Wrists, Hand, Carpal

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L03.90 • 4 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Cellulitis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Cellulitis?

Cellulitis is an infection of the skin and deep underlying tissues. Group A strep ( streptococcal ) bacteria are the most common cause. The bacteria enter your body when you get an injury such as a bruise, burn, surgical cut, or wound. Symptoms include: Fever and chills Swollen glands or lymph nodes A rash with painful, red, tender skin. The skin may blister and scab over. Your health care provider may take a sample or culture from your skin or do a blood test to identify the bacteria causing infection. Treatment is with antibiotics. They may be oral in mild cases, or intravenous (by IV) for more severe cases.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Cellulitis (ICD-10 L03.90) is driven by or latent viral in Cellulitis (L03.90: reactivation within sensory); Cross-referenced with NIH MeSH (Cellulitis), specialists in Bacterial, Viral & Fungal Infections monitor Targeted PCR / in Cellulitis (L03.90: Culture & Sensitivity) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Swollen glands or lymph nodes
  • • A rash with painful, red, tender skin. The skin may blister and scab over
  • • Presentation of Cellulitis (L03.90): sore throat, productive in Cellulitis (L03.90: cough, sinus/ear pain,)
  • • Secondary Cellulitis clinical sign: painful vesicular rash in Cellulitis (L03.90: in a dermatomal)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Cellulitis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L03.90 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Bacterial, Viral & Fungal Infections NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: C-Reactive Protein / in Cellulitis (L03.90: Procalcitonin) Resolution to baseline (L03.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Targeted PCR / in Cellulitis (L03.90: Culture & Sensitivity) Pathogen clearance / negative test (L03.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in Cellulitis (L03.90: (WBC & Differential)) WBC 4.0 – 10.0 x10^3/uL (L03.90) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Cellulitis

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Treatment selection for Cellulitis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Cellulitis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Effectiveness of postoperative oral administration of cephalexin and: What a 210-Participant Study Found

Post-operative administration of cephalexin and metronidazole for 48-h post-cesarean delivery among obese women, in addition to the standard pre-operative prophylaxis, reduced the overall rate of surgical site infection and...

Antimicrobial resistance and infection control • 2022-12-05 • Phase III Randomized Trial
N = 210 88/100 PMID 36471429 ↗
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