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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L98.1

Compulsive scratching

Also known as: Excoriation - neurotic

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L98.1 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
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Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Compulsive scratching Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Compulsive scratching?

Recognized across U.S. clinical coding as L98.1 (Skin & Dermatology), Compulsive scratching (also termed Excoriation - neurotic) is evaluated via contact/systemic trigger review [Compulsive scratching L98.1] to align day-to-day symptom relief with long-term physiological stability.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in skin & dermatology, Compulsive scratching (L98.1) involves cutaneous immune skewing in Compulsive scratching (L98.1: (Th2/IL-4/IL-13 in atopic). progression correlates with shifts in Affected Body Surface in Compulsive scratching (L98.1: Area (BSA /) (Clear or Almost Clear (IGA 0–1) (L98.1)).

Common Symptoms & Clinical Signs

  • • Presentation of Compulsive scratching (L98.1): compromised epidermal barrier in Compulsive scratching (L98.1: with dryness, fissuring,)
  • • Secondary Compulsive scratching clinical sign: post-inflammatory hyperpigmentation, facial in Compulsive scratching (L98.1: flushing, or pitted)
  • • Symptom flares in Compulsive scratching correlating with Affected Body Surface in Compulsive scratching (L98.1: Area (BSA /) deviation outside Clear or Almost Clear (IGA 0–1) (L98.1)
  • • Functional skin & dermatology impact requiring contact/systemic trigger review [Compulsive scratching L98.1] evaluation (L98.1)

Compulsive scratching Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L98.1 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Affected Body Surface in Compulsive scratching (L98.1: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L98.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Compulsive scratching (L98.1: ALT (if systemic) Within baseline reference limits (L98.1) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Compulsive scratching (L98.1: & hs-CRP) 25(OH)D 40–65 ng/mL (L98.1) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Compulsive scratching

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Compulsive scratching)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Baricitinib in combination with skin-applied steroids on eczema symptoms, quality: What a 329-Participant Study Found

Baricitinib plus TCS vs.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2021-07-15 • Phase III Randomized Trial
N = 329 93/100 PMID 33834521 ↗
New Insights on Early and Sustained Acne Lesion Reductions With Fixed-Dose Clindamycin Phosphate: What a 741-Participant Study Found

Lesion count reductions were significantly greater with CAB versus its dyads and vehicle gel as early as week 4, with substantial reductions observed after 12 weeks of treatment.

Journal of drugs in dermatology : JDD • 2024-03-01 • Phase III Randomized Trial
N = 741 93/100 PMID 38443130 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of dupilumab in patients with severe chronic hand eczema with

Dupilumab was efficacious and well tolerated.

The British journal of dermatology • 2023-09-15 • Randomized Controlled Trial
N = 20 88/100 PMID 37170922 ↗
Can This Approach Help? Inside the Latest Research on Acitretin versus etretinate in severe psoriasis. A gold-standard blind randomized

The differences found between acitretin and etretinate may be related to higher maximum plasma concentrations of acitretin.

Acta dermato-venereologica. Supplementum • 1989-01-15 • Randomized Controlled Trial
N = 127 88/100 PMID 2532847 ↗
Can This Approach Help? Inside the Latest Research on Regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in

These exploratory clinical improvements are accompanied by sustained increases in CD25 bright Tregs.

Nature communications • 2024-10-25 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 39455575 ↗
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