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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L25.9

Dermatitis - contact

Also known as: Dandruff, Seborrhea, Seborrheic, Dermatitis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L25.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Dermatitis - contact Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Dermatitis - contact?

For patients presenting with Dermatitis - contact (also termed Dandruff or Seborrhea) (ICD-10-CM L25.9), Dermatology: Acne, Eczema, Psoriasis & Rosacea protocols prioritize contact/systemic trigger review [Dermatitis - contact L25.9] paired with baseline and interval 25-Hydroxy Vitamin D in Dermatitis - contact (L25.9: & hs-CRP) assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in skin & dermatology, Dermatitis - contact (L25.9) involves keratinocyte hyperproliferation [Dermatitis - contact L25.9]. progression correlates with shifts in 25-Hydroxy Vitamin D in Dermatitis - contact (L25.9: & hs-CRP) (25(OH)D 40–65 ng/mL (L25.9)).

Common Symptoms & Clinical Signs

  • • Presentation of Dermatitis - contact (L25.9): persistent erythematous plaques, in Dermatitis - contact (L25.9: scaly patches, pruritic)
  • • Secondary Dermatitis - contact clinical sign: compromised epidermal barrier in Dermatitis - contact (L25.9: with dryness, fissuring,)
  • • Symptom flares in Dermatitis - contact correlating with 25-Hydroxy Vitamin D in Dermatitis - contact (L25.9: & hs-CRP) deviation outside 25(OH)D 40–65 ng/mL (L25.9)
  • • Functional skin & dermatology impact requiring contact/systemic trigger review [Dermatitis - contact L25.9] evaluation (L25.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Dermatitis - contact Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L25.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Dermatitis - contact (L25.9: & hs-CRP) 25(OH)D 40–65 ng/mL (L25.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Dermatitis - contact (L25.9: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L25.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Dermatitis - contact (L25.9: ALT (if systemic) Within baseline reference limits (L25.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Dermatitis - contact

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Dapsone Aczone • RxCUI 197557 Sulfone 90% $0.5828 $ 11.04 /mo
Nickel Sulfate, Potassium Bromide, and Fumaric Acid Psorizide Forte • RxCUI RXN-61480255-1781 FDA Prescription Therapeutic Agent 76% $1.7700 $ 80.19 /mo
Aczone (Dapsone) Aczone • RxCUI 197557-B16110526 Sulfone 90% $1.0480 $ 11.04 /mo
Pureskin Seborrheic Dermatitis and Psoriasis Cream (Seborrheic Dermatitis Psoriasis Cream) Pureskin Seborrheic Dermatitis and Psoriasis Cream • RxCUI 317152 Over-the-Counter Clinical Monograph 85% $2.9400 $ 220.18 /mo
Dapsone 25 Mg (Dapsone Tablets) Dapsone 25 Mg • RxCUI RXN-B83098102 Sulfone 92% $1.0480 $ 83.95 /mo
Oral Ivy Liquid (Toxicodendron Pubescens Leaf) Oral Ivy Liquid • RxCUI RXN-B684662015 Over-the-Counter Clinical Monograph 77% $1.5700 $ 121.54 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Dermatitis - contact)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Integrated Safety Analysis of Abrocitinib for the Treatment of Moderate-to-Severe: What a 2,856-Participant Study Found

Abrocitinib, with proper patient and dose selection, has a manageable tolerability and longer-term safety profile appropriate for long-term use in patients with moderate-to-severe AD.

American journal of clinical dermatology • 2021-09-15 • Phase III Randomized Trial
N = 2,856 96/100 PMID 34406619 ↗
New Insights on Dupilumab provides rapid and sustained improvement in SCORAD outcomes in adults: What a 2,444-Participant Study Found

In four large phase 3 trials in adults with moderate-to-severe AD, dupilumab treatment with or without concomitant TCS resulted in rapid and sustained improvements in all SCORAD outcomes vs.

The Journal of dermatological treatment • 2022-02-15 • Phase III Randomized Trial
N = 2,444 96/100 PMID 32347763 ↗
New Insights on Immunogenicity of dupilumab in adult and children patients with: What a 2,992-Participant Study Found

In patients with AD, ADAs and NAbs had minimal impact on dupilumab concentration, efficacy, and safety, except for high-titer ADAs in a small number of patients.

Frontiers in immunology • 2024-01-15 • Phase III Randomized Trial
N = 2,992 96/100 PMID 39588375 ↗
New Insights on Upadacitinib for moderate-to-severe eczema: Stratified analysis from three: What a 2,584-Participant Study Found

Upadacitinib had consistently high skin clearance rates and itch efficacy across subgroups of patients with moderate-to-severe AD through Week 16.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2023-09-15 • Phase III Randomized Trial
N = 2,584 96/100 PMID 37247226 ↗
New Insights on Bilateral Association Between eczema® and hair loss: What a 233,448-Participant Study Found

Based on 7 studies, there was a significant association between AD and AA when AA was the exposure factor [odds ratio, OR, = 4.537 (95% CI: 2.409-8.544)]; based on 10 studies, there was also a significant association between...

Dermatitis : contact, atopic, occupational, drug • 2024-01-15 • Meta-Analysis
N = 233,448 94/100 PMID 37471232 ↗
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