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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L85.0

Dry skin (xerosis)

Also known as: Xerosis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L85.0 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Dry skin (xerosis) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Dry skin (xerosis)?

Cataloged under federal diagnostic code L85.0 in Skin & Dermatology, Dry skin (xerosis) (also termed Xerosis) requires dermoscopy or punch in Dry skin (xerosis) (L85.0: biopsy when atypical) so specialists can calibrate treatment intensity against 25-Hydroxy Vitamin D in Dry skin (xerosis) (L85.0: & hs-CRP) benchmarks.

Pathophysiology, Underlying Causes & Clinical Presentation

In Dry skin (xerosis) (L85.0), physiological disruption stems from cutaneous immune skewing in Dry skin (xerosis) (L85.0: (Th2/IL-4/IL-13 in atopic), informing Dermatology: Acne, Eczema, Psoriasis & Rosacea protocols that track Affected Body Surface in Dry skin (xerosis) (L85.0: Area (BSA /) (Clear or Almost Clear (IGA 0–1) (L85.0)).

Common Symptoms & Clinical Signs

  • • Presentation of Dry skin (xerosis) (L85.0): compromised epidermal barrier in Dry skin (xerosis) (L85.0: with dryness, fissuring,)
  • • Secondary Dry skin (xerosis) clinical sign: post-inflammatory hyperpigmentation, facial in Dry skin (xerosis) (L85.0: flushing, or pitted)
  • • Symptom flares in Dry skin (xerosis) correlating with 25-Hydroxy Vitamin D in Dry skin (xerosis) (L85.0: & hs-CRP) deviation outside 25(OH)D 40–65 ng/mL (L85.0)
  • • Functional skin & dermatology impact requiring dermoscopy or punch in Dry skin (xerosis) (L85.0: biopsy when atypical) evaluation (L85.0)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Dry skin (xerosis) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L85.0 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Dry skin (xerosis) (L85.0: & hs-CRP) 25(OH)D 40–65 ng/mL (L85.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Dry skin (xerosis) (L85.0: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L85.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Dry skin (xerosis) (L85.0: ALT (if systemic) Within baseline reference limits (L85.0) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Dry skin (xerosis)

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Ammonium Lactate Lac-Hydrin • RxCUI 197362 alpha-Hydroxy Acid 78% $0.0624 $ 12.02 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Dry skin (xerosis))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients: What a 1,614-Participant Study Found

Once-daily treatment with tazarotene 0.045% polymeric emulsion lotion may help improve patient-perceived skin oiliness in those with moderate-to-severe acne.

The Journal of dermatological treatment • 2023-12-15 • Randomized Controlled Trial
N = 1,614 96/100 PMID 36382987 ↗
New Insights on Accuracy of ESAT6-CFP10 skin test compared with tuberculin skin test in a healthy: What a 1,564-Participant Study Found

The diagnostic performance of the EC skin test was similar to that of the T-SPOT test in the healthy population and was unaffected by BCG vaccination.

BMC infectious diseases • 2024-12-30 • Phase III Randomized Trial
N = 1,564 96/100 PMID 39736611 ↗
New Insights on Incidence of tardive dyskinesia in the study of pharmacotherapy for psychotic: What a 259-Participant Study Found

The incidence of TD was relatively low in both younger and older patients with depression with psychotic features treated acutely with olanzapine.

Journal of clinical psychopharmacology • 2013-06-15 • Randomized Controlled Trial
N = 259 93/100 PMID 23609383 ↗
New Insights on Psychometric evaluation of the Worst severe itching Numerical Rating Scale (NRS),: What a 769-Participant Study Found

These results provide evidence that the scores produced by the Worst severe itching NRS, ADerm-SS, and ADerm-IS are reliable and construct-valid when completed by adults and adolescents with moderate to severe AD in a clinical...

Current medical research and opinion • 2023-10-15 • Phase III Randomized Trial
N = 769 93/100 PMID 37691437 ↗
New Insights on Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute: What a 335-Participant Study Found

TARGET demonstrated that ceftobiprole is noninferior to vancomycin/aztreonam in the treatment of ABSSSIs, in terms of early clinical response and investigator-assessed clinical success at the TOC visit.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2021-10-05 • Phase III Randomized Trial
N = 335 93/100 PMID 32897367 ↗
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