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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L20.9

Eczema

Also known as: Dermatitis, Allergy, Alrgy, Allergic, Allergies

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L20.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Eczema Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Eczema?

Eczema is a term for several different types of skin swelling. Eczema is also called dermatitis. Most types cause dry, itchy skin and rashes on the face, inside the elbows and behind the knees, and on the hands and feet. Scratching the skin can cause it to turn red, and to swell and itch even more. Eczema is not contagious. The cause of eczema is unknown. It is likely caused by both genetic and environmental factors. Eczema may get better or worse over time, but it is often a long-lasting disease. People who have it may also develop hay fever and asthma. The most common type of eczema is atopic dermatitis.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Eczema (L20.9) features or pilosebaceous follicular in Eczema (L20.9: hyperkeratinization). Cross-referenced with NIH MeSH (Eczema), therapeutic stabilization in skin & dermatology is verified against 25-Hydroxy Vitamin D in Eczema (L20.9: & hs-CRP).

Common Symptoms & Clinical Signs

  • • Things that irritate your skin, such as certain soaps, fabrics, and lotions
  • • Things you are allergic to, such as food, pollen, and animals
  • • Presentation of Eczema (L20.9): persistent erythematous plaques, in Eczema (L20.9: scaly patches, pruritic)
  • • Secondary Eczema clinical sign: compromised epidermal barrier in Eczema (L20.9: with dryness, fissuring,)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Eczema Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L20.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Fasting Lipids & in Eczema (L20.9: ALT (if systemic) Within baseline reference limits (L20.9) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Eczema (L20.9: & hs-CRP) 25(OH)D 40–65 ng/mL (L20.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Eczema (L20.9: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L20.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Eczema

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Roycederm Eczema Relief Cream (Colloidal Oatmeal 1%) Roycederm Eczema Relief Cream • RxCUI 240651-B85424010 Non-Standardized Food Allergenic Extract 92% $0.9000 $ 73.30 /mo
Triderma Eczema Fast Healing Face Body (E Relief) Triderma Eczema Fast Healing Face Body • RxCUI 1189915 Non-Standardized Food Allergenic Extract 83% $2.7700 $ 207.94 /mo
Colloidal Oatmeal Soothing Moisturizing, Eczema Itch Relief Wash and Shampo • RxCUI 2396990 Non-Standardized Food Allergenic Extract 81% $3.3700 $ 144.99 /mo
Serawise Eczema Relief (Oatmeal) Serawise Eczema Relief • RxCUI 240651-B85050012 Non-Standardized Food Allergenic Extract 93% $3.3100 $ 246.82 /mo
Eczema (Oatmeal) Eczema • RxCUI 1437616-B52915010 Non-Standardized Food Allergenic Extract 83% $0.3200 $ 31.54 /mo
Eczema Itch Relief Wash and Shampo (Colloidal Oatmeal) Eczema Itch Relief Wash and Shampo • RxCUI 2396990-B10738162 Non-Standardized Food Allergenic Extract 88% $2.3500 $ 177.70 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Eczema)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Effect of Delgocitinib Cream on Health-Related Quality of Life in Patients With: What a 639-Participant Study Found

Delgocitinib cream resulted in clinically significant improvement in HRQoL compared with cream vehicle.

Contact dermatitis • 2026-07-15 • Phase III Randomized Trial
N = 639 93/100 PMID 41775339 ↗
New Insights on Absolute Eczema Area and Severity Index Responses with Lebrikizumab in Patients: What a 564-Participant Study Found

LEB was associated with high rates of durable absolute EASI response, even in cases of high baseline severity or suboptimal week-16 outcomes.

Acta dermato-venereologica • 2026-05-21 • Phase III Randomized Trial
N = 564 93/100 PMID 42163822 ↗
What the Latest Evidence Really Says About Factors associated with depression, anxiety and severe mental illness among

Our review highlights limited existing research on factors associated with depression, anxiety and SMI in adults with AE or psoriasis.

The British journal of dermatology • 2023-03-30 • Meta-Analysis
Multi-cohort 92/100 PMID 36745557 ↗
Can This Approach Help? Inside the Latest Research on A multicenter, randomized, double-blinded, compared against a dummy pill

Picankibart provided effective skin clearance in Chinese participants by week 16.

Journal of the American Academy of Dermatology • 2026-07-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 41937031 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of dupilumab in patients with severe chronic hand eczema with

Dupilumab was efficacious and well tolerated.

The British journal of dermatology • 2023-09-15 • Randomized Controlled Trial
N = 20 88/100 PMID 37170922 ↗
Zero-PHI Patient Support & Cohort Discussions

Eczema Patient Community & “People Like Me” Threads

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