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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L20.82

Flexural eczema

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L20.82 • 6 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Flexural eczema Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Flexural eczema?

For patients presenting with Flexural eczema (ICD-10-CM L20.82), Dermatology: Acne, Eczema, Psoriasis & Rosacea protocols prioritize or targeted biologics [Flexural eczema L20.82] paired with baseline and interval Affected Body Surface in Flexural eczema (L20.82: Area (BSA /) assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in skin & dermatology, Flexural eczema (L20.82) involves epidermal barrier filaggrin/ceramide in Flexural eczema (L20.82: disruption). progression correlates with shifts in Affected Body Surface in Flexural eczema (L20.82: Area (BSA /) (Clear or Almost Clear (IGA 0–1) (L20.82)).

Common Symptoms & Clinical Signs

  • • Presentation of Flexural eczema (L20.82): post-inflammatory hyperpigmentation, facial in Flexural eczema (L20.82: flushing, or pitted)
  • • Secondary Flexural eczema clinical sign: recurrent flares triggered in Flexural eczema (L20.82: by UV exposure,)
  • • Symptom flares in Flexural eczema correlating with Affected Body Surface in Flexural eczema (L20.82: Area (BSA /) deviation outside Clear or Almost Clear (IGA 0–1) (L20.82)
  • • Functional skin & dermatology impact requiring or targeted biologics [Flexural eczema L20.82] evaluation (L20.82)

Flexural eczema Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L20.82 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Affected Body Surface in Flexural eczema (L20.82: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L20.82) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Flexural eczema (L20.82: ALT (if systemic) Within baseline reference limits (L20.82) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Flexural eczema (L20.82: & hs-CRP) 25(OH)D 40–65 ng/mL (L20.82) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Flexural eczema

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Treatment selection for Flexural eczema depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Flexural eczema)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Benefits and safety of a New Botulinum Toxin (HU-014) Versus Existing: What a 267-Participant Study Found

HU-014 was noninferior to existing onabotulinumtoxin A in the treatment of glabellar lines at a 1:1 dose ratio, and both products were well tolerated.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] • 2021-03-01 • Phase III Randomized Trial
N = 267 93/100 PMID 33481449 ↗
Can This Approach Help? Inside the Latest Research on Effect of upadacitinib on atopic hand eczema in patients with moderate-to-severe

Upadacitinib 15 mg and 30 mg single-drug treatment provided rapid and sustained improvement in atopic hand eczema compared with placebo through Week 16 in patients with moderate-to-severe AD.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2023-09-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 37184290 ↗
Can This Approach Help? Inside the Latest Research on Aesthetic Improvements Over Time: Long-Term Efficacy and Additional Outcomes of

Additional endpoints, including pGAIS, iGAIS, and MAS scores, corroborate prior ULTRAI/II findings and demonstrate the efficacy of incobotulinumtoxinA for simultaneous treatment of UFLs.

Journal of cosmetic dermatology • 2025-09-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 40968493 ↗
Can This Approach Help? Inside the Latest Research on Patient-reported outcomes from the JADE COMPARE randomized phase 3 study of

Significant improvements in PROs were demonstrated with both abrocitinib doses vs.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2022-03-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 34779063 ↗
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