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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L40.4

Guttate psoriasis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L40.4 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Guttate psoriasis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Guttate psoriasis?

Clinical triage of Guttate psoriasis (L40.4) in Skin & Dermatology relies on topical retinoids/calcineurin/steroid sparing in Guttate psoriasis (L40.4: regimens), guiding step-wise therapeutic adjustments toward 25-Hydroxy Vitamin D in Guttate psoriasis (L40.4: & hs-CRP) (25(OH)D 40–65 ng/mL (L40.4)).

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Guttate psoriasis (L40.4) center on cutaneous immune skewing in Guttate psoriasis (L40.4: (Th2/IL-4/IL-13 in atopic). targeted skin & dermatology interventions aim to normalize Fasting Lipids & in Guttate psoriasis (L40.4: ALT (if systemic).

Common Symptoms & Clinical Signs

  • • Presentation of Guttate psoriasis (L40.4): compromised epidermal barrier in Guttate psoriasis (L40.4: with dryness, fissuring,)
  • • Secondary Guttate psoriasis clinical sign: post-inflammatory hyperpigmentation, facial in Guttate psoriasis (L40.4: flushing, or pitted)
  • • Symptom flares in Guttate psoriasis correlating with Fasting Lipids & in Guttate psoriasis (L40.4: ALT (if systemic) deviation outside Within baseline reference limits (L40.4)
  • • Functional skin & dermatology impact requiring topical retinoids/calcineurin/steroid sparing in Guttate psoriasis (L40.4: regimens) evaluation (L40.4)

Guttate psoriasis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L40.4 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Fasting Lipids & in Guttate psoriasis (L40.4: ALT (if systemic) Within baseline reference limits (L40.4) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Guttate psoriasis (L40.4: & hs-CRP) 25(OH)D 40–65 ng/mL (L40.4) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Guttate psoriasis (L40.4: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L40.4) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Guttate psoriasis

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Treatment selection for Guttate psoriasis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Guttate psoriasis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Acitretin versus etretinate in psoriasis. Clinical and how the body absorbs the

Three weeks after cessation of drug administration, the plasma concentrations of acitretin were below the sensitivity level of the assay, whereas etretinate was still quantifiable.

Journal of the American Academy of Dermatology • 1988-09-15 • Randomized Controlled Trial
N = 175 88/100 PMID 2971692 ↗
New Insights on Phase 3 trial demonstrating high efficacy, favourable safety and convenience of a: What a 490-Participant Study Found

CAL/BDP PAD-cream is a novel applied to the skin treatment of psoriasis that has a high efficacy and a favourable safety profile combined with a superior patient-reported treatment convenience.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2023-11-15 • Phase III Randomized Trial
N = 490 87/100 PMID 37432045 ↗
New Insights on Biosimilar SB17 versus reference ustekinumab in moderate to severe plaque: What a 503-Participant Study Found

SB17 demonstrated clinical biosimilarity to UST after switching from UST, and maintained long-term comparable real-world benefits and safety with UST up to Week 52.

The Journal of dermatological treatment • 2024-12-15 • Phase III Randomized Trial
N = 503 87/100 PMID 39658004 ↗
Can This Approach Help? Inside the Latest Research on Polymer oxygenated alginate dressings for healing skin graft donor areas: A phase

Our results demonstrate that POA dressing is safe and clinically effective for treating split-thickness skin graft donor site wounds.

Burns : journal of the International Society for Burn Injuries • 2026-04-15 • Phase III Randomized Trial
N = 69 82/100 PMID 41713054 ↗
Can This Approach Help? Inside the Latest Research on Cumulative irritancy comparison of skin-applied retinoid and antimicrobial

Adapalene gel 0.1% has tolerability superior to both tazarotene cream 0.05% and tretinoin microsphere 0.04% when used in applied to the skin combination therapy.

Skinmed • 2006-01-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 16957432 ↗
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