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IBS, Crohn, Colitis & Bowel Disorders • ICD-10-CM K50.9

Iron

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM K50.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Iron Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Iron?

What is iron? Iron is a mineral that our bodies need for growth and development. Your body uses iron to make hemoglobin, a protein in red blood cells. Hemoglobin carries oxygen from the lungs to all parts of the body. Iron is also important for healthy muscles, bone marrow, and organ function. Your body also needs iron to make some hormones . How do you get iron? Iron is found naturally in many foods and is added to some fortified food products.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Iron (K50.9) features mucosal tight-junction permeability in Iron (K50.9: shifts or immune-mediated). Cross-referenced with NIH MeSH (Iron), therapeutic stabilization in ibs, ibd & colon is verified against Fecal Calprotectin [Iron K50.9].

Common Symptoms & Clinical Signs

  • • Lean meat, seafood, and poultry
  • • Iron-fortified breakfast cereals and breads
  • • Presentation of Iron (K50.9): rectal bleeding, nocturnal in Iron (K50.9: bowel movements, or)
  • • Secondary Iron clinical sign: recurrent lower abdominal in Iron (K50.9: cramping associated with)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Iron Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code K50.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub IBS, Crohn, Colitis & Bowel Disorders NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: hs-CRP, CBC & in Iron (K50.9: Ferritin) Normal hemoglobin; hs-CRP < 1.0 mg/L (K50.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Fecal Calprotectin [Iron K50.9] < 50 mcg/g (K50.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Tissue Transglutaminase IgA in Iron (K50.9: (tTG-IgA)) Negative (celiac rule-out) (K50.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Iron

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Treatment selection for Iron depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Iron)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on A phase 3, multicenter, randomized, gold-standard blind, vehicle-controlled,: What a 281-Participant Study Found

In the sofpironium group, common events (incidence, ≥5%) were nasopharyngitis (14.2%) and dermatitis/skin redness at the application site (8.5%/5.7%), with no serious side effects reported.

The Journal of dermatology • 2021-03-15 • Phase III Randomized Trial
N = 281 93/100 PMID 33410265 ↗
New Insights on Benefits and safety of Subcutaneous Vedolizumab in Patients With Moderately to: What a 275-Participant Study Found

Vedolizumab SC is an effective and safe maintenance therapy in patients with CD who responded to two infusions of vedolizumab intravenous induction therapy.

Journal of Crohn's & colitis • 2022-01-28 • Phase III Randomized Trial
N = 275 93/100 PMID 34402887 ↗
New Insights on Sofpironium skin-applied gel, 12.45%, for the treatment of axillary: What a 353-Participant Study Found

Sofpironium applied to the skin gel, 12.45%, applied topically once daily before bedtime is effective and well-tolerated for treatment of primary axillary hyperhidrosis in patients ≥9 years old.

Journal of the American Academy of Dermatology • 2025-07-15 • Phase III Randomized Trial
N = 353 93/100 PMID 40054501 ↗
Can This Approach Help? Inside the Latest Research on Markers of Iron Flux during Testosterone-Mediated Erythropoiesis in Older Men

Testosterone replacement of older hypogonadal men with unexplained anemia stimulates erythropoiesis associated with increased iron mobilization.

The Journal of clinical endocrinology and metabolism • 2020-11-01 • Randomized Controlled Trial
N = 58 88/100 PMID 32785689 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of ferric carboxymaltose infusion in reducing anemia in

Common side effects in the FCM arm included neutropenia (17%), hypophosphatemia (16%), and fatigue (15%).

American journal of hematology • 2021-12-01 • Phase III Randomized Trial
N = 122 88/100 PMID 34653287 ↗
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Iron Patient Community & “People Like Me” Threads

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