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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L85.1

Keratoderma - acquired

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L85.1 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Keratoderma - acquired Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Keratoderma - acquired?

Under Dermatology: Acne, Eczema, Psoriasis & Rosacea diagnostic criteria (L85.1), workup for Keratoderma - acquired integrates dermoscopy or punch in Keratoderma - acquired (L85.1: biopsy when atypical) with evidence-graded therapy tailored to Affected Body Surface in Keratoderma - acquired (L85.1: Area (BSA /) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Keratoderma - acquired (L85.1) features epidermal barrier filaggrin/ceramide in Keratoderma - acquired (L85.1: disruption). therapeutic stabilization in skin & dermatology is verified against Fasting Lipids & in Keratoderma - acquired (L85.1: ALT (if systemic).

Common Symptoms & Clinical Signs

  • • Presentation of Keratoderma - acquired (L85.1): post-inflammatory hyperpigmentation, facial in Keratoderma - acquired (L85.1: flushing, or pitted)
  • • Secondary Keratoderma - acquired clinical sign: recurrent flares triggered in Keratoderma - acquired (L85.1: by UV exposure,)
  • • Symptom flares in Keratoderma - acquired correlating with Affected Body Surface in Keratoderma - acquired (L85.1: Area (BSA /) deviation outside Clear or Almost Clear (IGA 0–1) (L85.1)
  • • Functional skin & dermatology impact requiring dermoscopy or punch in Keratoderma - acquired (L85.1: biopsy when atypical) evaluation (L85.1)

Keratoderma - acquired Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L85.1 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Affected Body Surface in Keratoderma - acquired (L85.1: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L85.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Keratoderma - acquired (L85.1: ALT (if systemic) Within baseline reference limits (L85.1) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Keratoderma - acquired (L85.1: & hs-CRP) 25(OH)D 40–65 ng/mL (L85.1) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Keratoderma - acquired

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Lefamulin Acetate Xenleta • RxCUI 2198948 Calculi Dissolution Agent 84% $1.7600 $ 79.78 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Keratoderma - acquired)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Benefits and safety of the ustekinumab biosimilar, Bmab 1200, versus reference

Bmab 1200 and reference ustekinumab had similar efficacy, safety, immunogenicity, and PK in patients with moderate-to-severe plaque psoriasis skin flare-ups skin flare-ups.

Expert opinion on biological therapy • 2025-08-15 • Phase III Randomized Trial
N = 191 88/100 PMID 40708530 ↗
Can This Approach Help? Inside the Latest Research on Tildrakizumab for moderate-to-severe plaque psoriasis skin flare-ups in Chinese

Tildrakizumab demonstrated durable efficacy through week 52 and was well tolerated in Chinese patients with moderate-to-severe plaque psoriasis skin flare-ups skin flare-ups.

Chinese medical journal • 2024-05-20 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 38192233 ↗
Can This Approach Help? Inside the Latest Research on Serious Gastrointestinal-Related side effects Among Psoriasis Patients Treated

No cases of IBD were observed and rates of GI SAEs were low through 4 years of treatment with guselkumab in two large trials of patients with psoriasis.

Journal of drugs in dermatology : JDD • 2021-08-01 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 34397205 ↗
What the Latest Evidence Really Says About Comorbidities Associated With Lichen

LPP is significantly associated with autoimmune disorders, thyroid diseases, and skin cancer.

International journal of dermatology • 2025-12-15 • Meta-Analysis
Multi-cohort 86/100 PMID 40579650 ↗
Can This Approach Help? Inside the Latest Research on Facial Skin With Conspicuous Enlarged Pores Closely Related to Severity of Facial

Moreover, the disease control rate (complete full symptom relief/partial full symptom relief/stable disease) of the primary disease was seen in 59.1%, 70.6%, and 87.0% of patients with an enlarged pore score of 1, 2, and 3,...

The Journal of dermatology • 2025-08-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 40503645 ↗
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Keratoderma - acquired Patient Community & “People Like Me” Threads

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