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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L28.0

Neurodermatitis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L28.0 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Neurodermatitis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Neurodermatitis?

Within Dermatology: Acne, Eczema, Psoriasis & Rosacea practice, Neurodermatitis (ICD-10 L28.0) is stratified through contact/systemic trigger review [Neurodermatitis L28.0], pairing targeted symptom control with longitudinal Affected Body Surface in Neurodermatitis (L28.0: Area (BSA /) surveillance.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Neurodermatitis (ICD-10 L28.0) is driven by keratinocyte hyperproliferation [Neurodermatitis L28.0]; specialists in Dermatology: Acne, Eczema, Psoriasis & Rosacea monitor Affected Body Surface in Neurodermatitis (L28.0: Area (BSA /) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Neurodermatitis (L28.0): persistent erythematous plaques, in Neurodermatitis (L28.0: scaly patches, pruritic)
  • • Secondary Neurodermatitis clinical sign: compromised epidermal barrier in Neurodermatitis (L28.0: with dryness, fissuring,)
  • • Symptom flares in Neurodermatitis correlating with 25-Hydroxy Vitamin D in Neurodermatitis (L28.0: & hs-CRP) deviation outside 25(OH)D 40–65 ng/mL (L28.0)
  • • Functional skin & dermatology impact requiring contact/systemic trigger review [Neurodermatitis L28.0] evaluation (L28.0)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Neurodermatitis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L28.0 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Neurodermatitis (L28.0: & hs-CRP) 25(OH)D 40–65 ng/mL (L28.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Neurodermatitis (L28.0: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L28.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Neurodermatitis (L28.0: ALT (if systemic) Within baseline reference limits (L28.0) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Neurodermatitis

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Treatment selection for Neurodermatitis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Neurodermatitis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Diflorasone diacetate: vasoconstrictor activity and clinical efficacy of a new: What a 384-Participant Study Found

On the basis of additional vasoconstrictor assay results, a 0-05% concentration of the steroid in a cream vehicle containing 15% propylene glycol was developed for therapeutic evaluation.

The Journal of international medical research • 1976-01-15 • Randomized Controlled Trial
N = 384 93/100 PMID 800385 ↗
Can This Approach Help? Inside the Latest Research on Triple-Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide

In 2 pooled phase 3 studies, once-daily CAB gel was well tolerated and efficacious in children participants with acne, with over half achieving treatment success at week 12.

Journal of drugs in dermatology : JDD • 2024-12-01 • Phase III Randomized Trial
N = 123 88/100 PMID 39630680 ↗
Can This Approach Help? Inside the Latest Research on Gold-standard blind paired comparison clinical trial of halcinonide and

No side effects with either ointment were observed.

Cutis • 1978-07-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 352631 ↗
Can This Approach Help? Inside the Latest Research on Human chorionic gonadotrophin is a better luteal support than progesterone in

We conclude that HCG is superior to i.m.

Human reproduction (Oxford, England) • 1993-09-15 • Randomized Controlled Trial
N = 60 82/100 PMID 8253920 ↗
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Neurodermatitis Patient Community & “People Like Me” Threads

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