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Fertility, Pregnancy & Postpartum Care • ICD-10-CM O26.40

Pemphigoid gestationis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM O26.40 • 4 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
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Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Pemphigoid gestationis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Pemphigoid gestationis?

Designated in federal medical registries as O26.40, Pemphigoid gestationis falls under Fertility & Pregnancy management, where semen analysis [Pemphigoid gestationis O26.40] establishes baseline severity and rules out diagnostic mimics.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Pemphigoid gestationis (ICD-10 O26.40) is driven by gestational human placental in Pemphigoid gestationis (O26.40: lactogen insulin resistance); specialists in Fertility, Pregnancy & Postpartum Care monitor Prenatal TSH, Ferritin in Pemphigoid gestationis (O26.40: & Glucose Screen) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Pemphigoid gestationis (O26.40): gestational fasting or in Pemphigoid gestationis (O26.40: post-load blood glucose)
  • • Secondary Pemphigoid gestationis clinical sign: inability to achieve in Pemphigoid gestationis (O26.40: clinical pregnancy after)
  • • Symptom flares in Pemphigoid gestationis correlating with Maternal Blood Pressure in Pemphigoid gestationis (O26.40: & Urine Protein) deviation outside BP < 120/80 mmHg; negative proteinuria (O26.40)
  • • Functional fertility & pregnancy impact requiring semen analysis [Pemphigoid gestationis O26.40] evaluation (O26.40)

Pemphigoid gestationis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code O26.40 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Fertility, Pregnancy & Postpartum Care NLM Clinical Tables
Diagnostic / Lab Marker: Maternal Blood Pressure in Pemphigoid gestationis (O26.40: & Urine Protein) BP < 120/80 mmHg; negative proteinuria (O26.40) Clinical Reference Target Range
Diagnostic / Lab Marker: Prenatal TSH, Ferritin in Pemphigoid gestationis (O26.40: & Glucose Screen) Trimester-specific clinical range (O26.40) Clinical Reference Target Range
Diagnostic / Lab Marker: Anti-Mullerian Hormone (AMH) in Pemphigoid gestationis (O26.40: & Day-3 FSH) Age-contextual ovarian reserve (O26.40) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Pemphigoid gestationis

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Treatment selection for Pemphigoid gestationis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Pemphigoid gestationis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Utero-placental perfusion Doppler indices in growth restricted fetuses: effect of

Sildenafil citrate, by its vasodilator effect, can improve utero-placental blood flow in pregnancies complicated by FGR and abnormal Doppler.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians • 2018-04-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 28345432 ↗
What the Latest Evidence Really Says About Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and

Observed associations are small and of very low to low certainty, reflecting incomplete ultraviolet-exposure and risk-factor adjustment; causality cannot be established.

European journal of clinical investigation • 2026-11-15 • Meta-Analysis
Multi-cohort 86/100 PMID 42924873 ↗
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