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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L05.91

Pilonidal dimple

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L05.91 • 5 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Pilonidal dimple Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Pilonidal dimple?

Designated in federal medical registries as L05.91, Pilonidal dimple falls under Skin & Dermatology management, where topical retinoids/calcineurin/steroid sparing in Pilonidal dimple (L05.91: regimens) establishes baseline severity and rules out diagnostic mimics.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in skin & dermatology, Pilonidal dimple (L05.91) involves cutaneous immune skewing in Pilonidal dimple (L05.91: (Th2/IL-4/IL-13 in atopic). progression correlates with shifts in Fasting Lipids & in Pilonidal dimple (L05.91: ALT (if systemic) (Within baseline reference limits (L05.91)).

Common Symptoms & Clinical Signs

  • • Presentation of Pilonidal dimple (L05.91): compromised epidermal barrier in Pilonidal dimple (L05.91: with dryness, fissuring,)
  • • Secondary Pilonidal dimple clinical sign: post-inflammatory hyperpigmentation, facial in Pilonidal dimple (L05.91: flushing, or pitted)
  • • Symptom flares in Pilonidal dimple correlating with Fasting Lipids & in Pilonidal dimple (L05.91: ALT (if systemic) deviation outside Within baseline reference limits (L05.91)
  • • Functional skin & dermatology impact requiring topical retinoids/calcineurin/steroid sparing in Pilonidal dimple (L05.91: regimens) evaluation (L05.91)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Pilonidal dimple Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L05.91 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Fasting Lipids & in Pilonidal dimple (L05.91: ALT (if systemic) Within baseline reference limits (L05.91) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Pilonidal dimple (L05.91: & hs-CRP) 25(OH)D 40–65 ng/mL (L05.91) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Pilonidal dimple (L05.91: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L05.91) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Pilonidal dimple)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
What the Latest Evidence Really Says About Genetic relationship between IL-10 gene polymorphisms and the risk of clinical

The current evidence does not support a strong genetic relationship between IL-10 -1082 A/G, - 819 T/C and - 592 A/C polymorphisms and the susceptibility to eczema.

BMC medical genetics • 2019-05-17 • Meta-Analysis
Multi-cohort 86/100 PMID 31101031 ↗
Can This Approach Help? Inside the Latest Research on Transdermal absorption of clindamycin and tretinoin from topically applied

The chemical form of clindamycin proved to modulate skin irritation and percutaneous uptake of clindamycin from a gel formulation in healthy subjects.

Biopharmaceutics & drug disposition • 1998-12-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 9872337 ↗
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