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Children's & Adolescent Health • ICD-10-CM Q82.8

Porokeratosis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM Q82.8 • 5 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Porokeratosis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Porokeratosis?

Physicians managing Porokeratosis (Q82.8; Children's & Adolescent Health) utilize growth-chart trajectory review [Porokeratosis Q82.8] and objective WHO / CDC in Porokeratosis (Q82.8: Age-Adjusted Growth Percentiles) targets (Consistent personal growth curve tracking (Q82.8)) to prevent progression and functional morbidity.

Pathophysiology, Underlying Causes & Clinical Presentation

Biological expression of Porokeratosis (Q82.8, Pediatrics) reflects or congenital embryologic in Porokeratosis (Q82.8: structural variation). longitudinal control is benchmarked via WHO / CDC in Porokeratosis (Q82.8: Age-Adjusted Growth Percentiles).

Common Symptoms & Clinical Signs

  • • Presentation of Porokeratosis (Q82.8): pediatric skin rashes, in Porokeratosis (Q82.8: gastrointestinal discomfort, or)
  • • Secondary Porokeratosis clinical sign: growth velocity shifts, in Porokeratosis (Q82.8: newborn feeding/jaundice signs,)
  • • Symptom flares in Porokeratosis correlating with WHO / CDC in Porokeratosis (Q82.8: Age-Adjusted Growth Percentiles) deviation outside Consistent personal growth curve tracking (Q82.8)
  • • Functional pediatrics impact requiring growth-chart trajectory review [Porokeratosis Q82.8] evaluation (Q82.8)

Porokeratosis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code Q82.8 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Children's & Adolescent Health NLM Clinical Tables
Diagnostic / Lab Marker: WHO / CDC in Porokeratosis (Q82.8: Age-Adjusted Growth Percentiles) Consistent personal growth curve tracking (Q82.8) Clinical Reference Target Range
Diagnostic / Lab Marker: Pediatric Hemoglobin & in Porokeratosis (Q82.8: Lead Screen) Age-normal hemoglobin; blood lead < 3.5 mcg/dL (Q82.8) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Porokeratosis

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Treatment selection for Porokeratosis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Porokeratosis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Phase 3 study of an Ad26.RSV.preF/RSV preF protein vaccine to evaluate the: What a 996-Participant Study Found

Although vaccine efficacy could not be concluded, it was immunogenic with acceptable safety profile in both Japanese younger and older adult population.

Respiratory investigation • 2025-07-15 • Phase III Randomized Trial
N = 996 93/100 PMID 40319702 ↗
Can This Approach Help? Inside the Latest Research on Pooled Results of Two Randomized Phase III Trials Evaluating VP-102, a

Pooled analyses showed a significantly higher percentage of participants with complete molluscum lesion clearance and larger reductions in lesion counts with VP-102 than with vehicle.

American journal of clinical dermatology • 2021-03-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 33599960 ↗
Can This Approach Help? Inside the Latest Research on Nipocalimab Phase 3 Dose Selection for Severe Hemolytic Disease of the Fetus and

Simulations incorporating PK/PD variability indicated that 45 mg/kg weekly per current weight maintained full FcRn occupancy in >95% of pregnant individuals, even with dosing delays up to 3 days.

Journal of clinical pharmacology • 2026-09-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 42726505 ↗
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Porokeratosis Patient Community & “People Like Me” Threads

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