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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L85.8

Pseudoepitheliomatous hyperplasia

Also known as: Hyperplasia, Hyperplastic, Hypertrophic, Hypertrophy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L85.8 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Pseudoepitheliomatous hyperplasia Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Pseudoepitheliomatous hyperplasia?

For patients presenting with Pseudoepitheliomatous hyperplasia (also termed Hyperplasia or Hyperplastic) (ICD-10-CM L85.8), Dermatology: Acne, Eczema, Psoriasis & Rosacea protocols prioritize dermoscopy or punch in Pseudoepitheliomatous hyperplasia (L85.8: biopsy when atypical) paired with baseline and interval Fasting Lipids & in Pseudoepitheliomatous hyperplasia (L85.8: ALT (if systemic) assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in skin & dermatology, Pseudoepitheliomatous hyperplasia (L85.8) involves or pilosebaceous follicular in Pseudoepitheliomatous hyperplasia (L85.8: hyperkeratinization). progression correlates with shifts in Fasting Lipids & in Pseudoepitheliomatous hyperplasia (L85.8: ALT (if systemic) (Within baseline reference limits (L85.8)).

Common Symptoms & Clinical Signs

  • • Presentation of Pseudoepitheliomatous hyperplasia (L85.8): persistent erythematous plaques, in Pseudoepitheliomatous hyperplasia (L85.8: scaly patches, pruritic)
  • • Secondary Pseudoepitheliomatous hyperplasia clinical sign: compromised epidermal barrier in Pseudoepitheliomatous hyperplasia (L85.8: with dryness, fissuring,)
  • • Symptom flares in Pseudoepitheliomatous hyperplasia correlating with Fasting Lipids & in Pseudoepitheliomatous hyperplasia (L85.8: ALT (if systemic) deviation outside Within baseline reference limits (L85.8)
  • • Functional skin & dermatology impact requiring dermoscopy or punch in Pseudoepitheliomatous hyperplasia (L85.8: biopsy when atypical) evaluation (L85.8)

Pseudoepitheliomatous hyperplasia Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L85.8 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Fasting Lipids & in Pseudoepitheliomatous hyperplasia (L85.8: ALT (if systemic) Within baseline reference limits (L85.8) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Pseudoepitheliomatous hyperplasia (L85.8: & hs-CRP) 25(OH)D 40–65 ng/mL (L85.8) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Pseudoepitheliomatous hyperplasia (L85.8: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L85.8) Clinical Reference Target Range
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Treatment selection for Pseudoepitheliomatous hyperplasia depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Pseudoepitheliomatous hyperplasia)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Characterization of acne associated with upadacitinib treatment in patients with

Acne associated with upadacitinib for eczema treatment is usually mild/moderate in severity and managed with applied to the skin therapies or no intervention.

Journal of the American Academy of Dermatology • 2022-10-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 35714786 ↗
Can This Approach Help? Inside the Latest Research on Isotretinoin and tetracycline in the management of severe nodulocystic

All patients on isotretinoin experienced side effects that were primarily related to the integumentary system but necessitated discontinuation of the drug for a short period of time in only one patient.

International journal of dermatology • 1985-05-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 3159698 ↗
What the Latest Evidence Really Says About Association between eczema and high blood

AD, particularly moderate-to-severe disease, was associated with increased high blood pressure compared with healthy controls, but with lower odds than for psoriasis.

The British journal of dermatology • 2022-02-15 • Meta-Analysis
Multi-cohort 86/100 PMID 34319589 ↗
What the Latest Evidence Really Says About Association between psoriasis and hair loss

This study suggests a bidirectional association between psoriasis and hair loss areata.

The Journal of dermatology • 2022-09-15 • Meta-Analysis
Multi-cohort 86/100 PMID 35510645 ↗
Can This Approach Help? Inside the Latest Research on Tretinoin Loaded Nanoemulsion for Acne Vulgaris: Fabrication, Physicochemical and

In a pilot clinical study, the number of acne lesions as well as the size and intensity of porphyrin production significantly reduced after applied to the skin application of NE-TRE.

Skin pharmacology and physiology • 2018-01-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 30199861 ↗
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