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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM F45.41

Skin pain - psychogenic

Also known as: Skin, Dermis, Cutis, Dermal

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM F45.41 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Skin pain - psychogenic Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Skin pain - psychogenic?

Skin pain - psychogenic (also termed Skin or Dermis) is an ICD-10-CM indexed diagnosis (F45.41) within Dermatology: Acne, Eczema, Psoriasis & Rosacea. Clinical evaluation centers on topical retinoids/calcineurin/steroid sparing in Skin pain - psychogenic (F45.41: regimens) alongside serial 25-Hydroxy Vitamin D in Skin pain - psychogenic (F45.41: & hs-CRP) tracking (25(OH)D 40–65 ng/mL (F45.41)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Skin pain - psychogenic (F45.41) center on keratinocyte hyperproliferation [Skin pain - psychogenic F45.41]. targeted skin & dermatology interventions aim to normalize 25-Hydroxy Vitamin D in Skin pain - psychogenic (F45.41: & hs-CRP).

Common Symptoms & Clinical Signs

  • • Presentation of Skin pain - psychogenic (F45.41): persistent erythematous plaques, in Skin pain - psychogenic (F45.41: scaly patches, pruritic)
  • • Secondary Skin pain - psychogenic clinical sign: compromised epidermal barrier in Skin pain - psychogenic (F45.41: with dryness, fissuring,)
  • • Symptom flares in Skin pain - psychogenic correlating with 25-Hydroxy Vitamin D in Skin pain - psychogenic (F45.41: & hs-CRP) deviation outside 25(OH)D 40–65 ng/mL (F45.41)
  • • Functional skin & dermatology impact requiring topical retinoids/calcineurin/steroid sparing in Skin pain - psychogenic (F45.41: regimens) evaluation (F45.41)

Skin pain - psychogenic Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code F45.41 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Skin pain - psychogenic (F45.41: & hs-CRP) 25(OH)D 40–65 ng/mL (F45.41) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Skin pain - psychogenic (F45.41: Area (BSA /) Clear or Almost Clear (IGA 0–1) (F45.41) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Skin pain - psychogenic (F45.41: ALT (if systemic) Within baseline reference limits (F45.41) Clinical Reference Target Range
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Treatment selection for Skin pain - psychogenic depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Skin pain - psychogenic)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients: What a 1,614-Participant Study Found

Once-daily treatment with tazarotene 0.045% polymeric emulsion lotion may help improve patient-perceived skin oiliness in those with moderate-to-severe acne.

The Journal of dermatological treatment • 2023-12-15 • Randomized Controlled Trial
N = 1,614 96/100 PMID 36382987 ↗
New Insights on Accuracy of ESAT6-CFP10 skin test compared with tuberculin skin test in a healthy: What a 1,564-Participant Study Found

The diagnostic performance of the EC skin test was similar to that of the T-SPOT test in the healthy population and was unaffected by BCG vaccination.

BMC infectious diseases • 2024-12-30 • Phase III Randomized Trial
N = 1,564 96/100 PMID 39736611 ↗
New Insights on Incidence of tardive dyskinesia in the study of pharmacotherapy for psychotic: What a 259-Participant Study Found

The incidence of TD was relatively low in both younger and older patients with depression with psychotic features treated acutely with olanzapine.

Journal of clinical psychopharmacology • 2013-06-15 • Randomized Controlled Trial
N = 259 93/100 PMID 23609383 ↗
New Insights on Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute: What a 335-Participant Study Found

TARGET demonstrated that ceftobiprole is noninferior to vancomycin/aztreonam in the treatment of ABSSSIs, in terms of early clinical response and investigator-assessed clinical success at the TOC visit.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2021-10-05 • Phase III Randomized Trial
N = 335 93/100 PMID 32897367 ↗
New Insights on Secukinumab maintains superiority over ustekinumab in clearing skin and improving: What a 550-Participant Study Found

This second head-to-head study confirmed the superior efficacy of secukinumab over ustekinumab in skin clearance and quality of life through 52 weeks, with safety comparable to that reported in previous trials.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2021-01-15 • Phase III Randomized Trial
N = 550 93/100 PMID 32365251 ↗
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Related Conditions in Dermatology: Acne, Eczema, Psoriasis & Rosacea