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Osteoarthritis, Gout & Joint Pain • ICD-10-CM M65.90

Tenosynovitis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M65.90 • 6 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Tenosynovitis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Tenosynovitis?

Recognized across U.S. clinical coding as M65.90 (Arthritis & Joints), Tenosynovitis is evaluated via urate-lowering titration [Tenosynovitis M65.90] to align day-to-day symptom relief with long-term physiological stability.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in arthritis & joints, Tenosynovitis (M65.90) involves monosodium urate or in Tenosynovitis (M65.90: calcium pyrophosphate crystal). progression correlates with shifts in Serum Uric Acid in Tenosynovitis (M65.90: (Gout Target)) (< 6.0 mg/dL (< 5.0 mg/dL with tophi) (M65.90)).

Common Symptoms & Clinical Signs

  • • Presentation of Tenosynovitis (M65.90): brief morning joint in Tenosynovitis (M65.90: stiffness)
  • • Secondary Tenosynovitis clinical sign: sudden, intensely painful, in Tenosynovitis (M65.90: red swollen big-toe)
  • • Symptom flares in Tenosynovitis correlating with Serum Uric Acid in Tenosynovitis (M65.90: (Gout Target)) deviation outside < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M65.90)
  • • Functional arthritis & joints impact requiring urate-lowering titration [Tenosynovitis M65.90] evaluation (M65.90)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Tenosynovitis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M65.90 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoarthritis, Gout & Joint Pain NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Serum Uric Acid in Tenosynovitis (M65.90: (Gout Target)) < 6.0 mg/dL (< 5.0 mg/dL with tophi) (M65.90) Clinical Reference Target Range
Diagnostic / Lab Marker: hs-CRP & Erythrocyte in Tenosynovitis (M65.90: Sedimentation Rate) hs-CRP < 1.5 mg/L; ESR < 15 mm/hr (M65.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Weight-Bearing Joint Radiograph [Tenosynovitis M65.90] Preserved joint-space width (M65.90) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Tenosynovitis

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Treatment selection for Tenosynovitis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Tenosynovitis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on A population how the body absorbs the medicine model using allometric scaling for

The PK modeling suggested the optimal dosing regimen based on weight for children patients as: 2-mg QD for patients 10 to <30 kg and 4-mg QD for patients ≥30 kg.

CPT: pharmacometrics & systems pharmacology • 2024-06-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 38532270 ↗
Can This Approach Help? Inside the Latest Research on Baseline Disease Activity Predicts Achievement of cDAPSA Treatment Targets With

Apremilast-treated patients with baseline ModDA had higher probability of achieving cDAPSA treatment targets than patients with HDA.

The Journal of rheumatology • 2022-07-15 • Phase III Randomized Trial
N = 126 88/100 PMID 35428720 ↗
New Insights on Potential Impact of Sex and BMI on Response to Therapy in Psoriatic Arthritis:: What a 851-Participant Study Found

Improved outcomes were observed more in.

The Journal of rheumatology • 2022-08-15 • Phase III Randomized Trial
N = 851 87/100 PMID 35428718 ↗
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