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Children's & Adolescent Health • ICD-10-CM Q21.3

Tetralogy of Fallot (TOF)

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM Q21.3 • 4 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Tetralogy of Fallot (TOF) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Tetralogy of Fallot (TOF)?

Physicians managing Tetralogy of Fallot (TOF) (Q21.3; Children's & Adolescent Health) utilize immunization schedule review [Tetralogy of Fallot (TOF) Q21.3] and objective WHO / CDC in Tetralogy of Fallot (TOF) (Q21.3: Age-Adjusted Growth Percentiles) targets (Consistent personal growth curve tracking (Q21.3)) to prevent progression and functional morbidity.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Tetralogy of Fallot (TOF) (ICD-10 Q21.3) is driven by or congenital embryologic in Tetralogy of Fallot (TOF) (Q21.3: structural variation); specialists in Children's & Adolescent Health monitor Pediatric Hemoglobin & in Tetralogy of Fallot (TOF) (Q21.3: Lead Screen) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Tetralogy of Fallot (TOF) (Q21.3): acute childhood fever, in Tetralogy of Fallot (TOF) (Q21.3: barking cough, wheezing,)
  • • Secondary Tetralogy of Fallot (TOF) clinical sign: developmental milestone questions in Tetralogy of Fallot (TOF) (Q21.3: across speech, motor)
  • • Symptom flares in Tetralogy of Fallot (TOF) correlating with WHO / CDC in Tetralogy of Fallot (TOF) (Q21.3: Age-Adjusted Growth Percentiles) deviation outside Consistent personal growth curve tracking (Q21.3)
  • • Functional pediatrics impact requiring immunization schedule review [Tetralogy of Fallot (TOF) Q21.3] evaluation (Q21.3)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Tetralogy of Fallot (TOF) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code Q21.3 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Children's & Adolescent Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: WHO / CDC in Tetralogy of Fallot (TOF) (Q21.3: Age-Adjusted Growth Percentiles) Consistent personal growth curve tracking (Q21.3) Clinical Reference Target Range
Diagnostic / Lab Marker: Pediatric Hemoglobin & in Tetralogy of Fallot (TOF) (Q21.3: Lead Screen) Age-normal hemoglobin; blood lead < 3.5 mcg/dL (Q21.3) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Tetralogy of Fallot (TOF)

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Treatment selection for Tetralogy of Fallot (TOF) depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Tetralogy of Fallot (TOF))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Efficacy, immunogenicity and safety of CoronaVac® in children and adolescents: What a 11,349-Participant Study Found

All the severe side effects were determined to be unrelated to the investigational products.

Nature communications • 2024-08-06 • Phase III Randomized Trial
N = 11,349 96/100 PMID 39107270 ↗
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