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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L29.89

Winter itch

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L29.89 • 6 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Winter itch Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Winter itch?

Cataloged under federal diagnostic code L29.89 in Skin & Dermatology, Winter itch requires topical retinoids/calcineurin/steroid sparing in Winter itch (L29.89: regimens) so specialists can calibrate treatment intensity against Fasting Lipids & in Winter itch (L29.89: ALT (if systemic) benchmarks.

Pathophysiology, Underlying Causes & Clinical Presentation

Winter itch (L29.89) alters skin & dermatology homeostasis through cutaneous immune skewing in Winter itch (L29.89: (Th2/IL-4/IL-13 in atopic); clinical remission targets 25-Hydroxy Vitamin D in Winter itch (L29.89: & hs-CRP) within 25(OH)D 40–65 ng/mL (L29.89).

Common Symptoms & Clinical Signs

  • • Presentation of Winter itch (L29.89): compromised epidermal barrier in Winter itch (L29.89: with dryness, fissuring,)
  • • Secondary Winter itch clinical sign: post-inflammatory hyperpigmentation, facial in Winter itch (L29.89: flushing, or pitted)
  • • Symptom flares in Winter itch correlating with Fasting Lipids & in Winter itch (L29.89: ALT (if systemic) deviation outside Within baseline reference limits (L29.89)
  • • Functional skin & dermatology impact requiring topical retinoids/calcineurin/steroid sparing in Winter itch (L29.89: regimens) evaluation (L29.89)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Winter itch Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L29.89 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Fasting Lipids & in Winter itch (L29.89: ALT (if systemic) Within baseline reference limits (L29.89) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Winter itch (L29.89: & hs-CRP) 25(OH)D 40–65 ng/mL (L29.89) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Winter itch (L29.89: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L29.89) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Winter itch

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Treatment selection for Winter itch depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Winter itch)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Effect of tralokinumab on moderate-to-severe eczema in patients with atopic

Regardless of the presence or number of self-reported atopic comorbidities, 16 weeks of tralokinumab treatment improved AD severity in adults and adolescents.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology • 2025-10-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 40555305 ↗
Can This Approach Help? Inside the Latest Research on Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel in

In two phase 3 clinical trials, fixed-dose, triple-combination CAB demonstrated good efficacy/safety.

Journal of drugs in dermatology : JDD • 2024-11-01 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 39496135 ↗
Can This Approach Help? Inside the Latest Research on A randomized, investigator-blinded trial to assess the antimicrobial efficacy of

These data suggest that clindamycin phosphate 1%/benzoyl peroxide 5% gel reduces P.

Journal of drugs in dermatology : JDD • 2010-02-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 20214175 ↗
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Winter itch Patient Community & “People Like Me” Threads

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