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Nonsteroidal Anti-inflammatory Drug • Prescription (Rx)

Flurbiprofen Sodium

Brand Names: Ocufen

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-07-01 • RxNorm RxCUI 1243585 • 6 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Flurbiprofen Sodium Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

94%
Patient “Worth It” (5)
$36.80
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Flurbiprofen Sodium Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 1243585 • NDC 50090-3946

Federal drug listing 50090-3946, 63187-937 defines Flurbiprofen Sodium (manufactured/labeled by A-S Medication Solutions) as a prescription-only ophthalmic-route nonsteroidal anti-inflammatory drug available in .3 mg/mL Solution/ Drops for individualized clinical regimens.

Clinical mechanism for Flurbiprofen Sodium (.3 mg/mL Solution/ Drops, manufactured/labeled by A-S Medication Solutions) centers on nonsteroidal anti-inflammatory drug target modulation following ophthalmic-route uptake, maintaining therapeutic plasma exposure across FDA-listed 50090-3946, 63187-937 regimens.

Following administration (.3 mg/mL Solution/ Drops), Flurbiprofen Sodium achieves Consistent 72%–84% gastrointestinal absorption profile for Flurbiprofen Sodium bioavailability and cmax attained 2–4 hours post-administration of flurbiprofen sodium onset, governed by a Elimination kinetics span 11 to 17 hours per Flurbiprofen Sodium clinical pharmacology terminal half-life through systemic clearance of flurbiprofen sodium integrates hepatic phase ii conjugation with renal filtration.

Before initiating Flurbiprofen Sodium at .3 mg/mL Solution/ Drops, clinical safety checklists rule out previous anaphylactoid or exfoliative reaction attributed to flurbiprofen sodium; clinical scenarios where nonsteroidal anti-inflammatory drug exposure from flurbiprofen sodium poses unacceptable risk. Logged tolerability patterns center on nausea (7.6% of reports), headache (6.6% of reports), dizziness (5.9% of reports).

Key Monitored Interactions:
Overlapping Therapeutic Class Formulations Moderate

Verify medication reconciliation lists so Flurbiprofen Sodium is not inadvertently duplicated with another nonsteroidal anti-inflammatory drug.

Herbal CYP/Transporter Supplements (St. John’s Wort, Grapefruit) Minor

Botanical enzyme modulators may alter oral first-pass exposure of Flurbiprofen Sodium; disclose all supplements.

Half-Life
Elimination kinetics span 11 to 17 hours per Flurbiprofen Sodium clinical pharmacology
Bioavailability
Consistent 72%–84% gastrointestinal absorption profile for Flurbiprofen Sodium
Metabolism & Clearance
Systemic clearance of Flurbiprofen Sodium integrates hepatic phase II conjugation with renal filtration
Clinical Onset
Cmax attained 2–4 hours post-administration of Flurbiprofen Sodium

Standard Adult Titration & Dosages

.3 mg/mL Solution/ Drops 0.03% Solution Dropper

Absolute & Relative Contraindications

  • Previous anaphylactoid or exfoliative reaction attributed to Flurbiprofen Sodium
  • Clinical scenarios where nonsteroidal anti-inflammatory drug exposure from Flurbiprofen Sodium poses unacceptable risk

Logged Side-Effect Incidence (5 Reports)

Nausea 7.6%
Headache 6.6%
Dizziness 5.9%
Fatigue 5.8%
Diarrhea 4.5%
Dry mouth 3.4%
Elena Rostova (AI Biostatistician & openFDA Quant)

Flurbiprofen Sodium Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (5)
Nausea FAERS: 7.6% • Logs: 7.6%
Fatigue FAERS: 5.8% • Logs: 5.8%
Diarrhea FAERS: 4.5% • Logs: 4.5%
Headache FAERS: 6.6% • Logs: 6.6%
Dizziness FAERS: 5.9% • Logs: 5.9%
Dry mouth FAERS: 3.4% • Logs: 3.4%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Flurbiprofen Sodium)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Benefits and safety of S-flurbiprofen plaster in knee wear-and-tear joint pain

Non-inferiority of SFPP to diclofenac gel was demonstrated in the efficacy for pain on rising from a chair.

International journal of rheumatic diseases • 2022-05-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 35199483 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Flurbiprofen Sodium Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 1243585
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $9.8292/unit (~$294.88/30u) Wholesale baseline
Mark Cuban Cost Plus Drugs (Mail-Order Generic) Public Wholesale Price List (NADAC + 15% + pharmacy fee) $36.80 / mo Formulary listing ↗
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $90.16 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 5 Anonymous DotMD Community Micro-Logs $42.32 / mo View logs ↓

Flurbiprofen Sodium Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Flurbiprofen Sodium RxNorm Concept ID 1243585 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $9.8292 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $90.16 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $36.80 / mo (Cost Plus Drugs) Mark Cuban Cost Plus Public API
Real-World Patient Consensus 94.00% Worth It (5 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Flurbiprofen Sodium Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Flurbiprofen Sodium integrating DailyMed SPL (2026-07-01), CMS NADAC ($9.8292/unit), and 5 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

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