Lidocaine, Phenylephrine Hydrochloride
Brand Names: The Femme Fix Hemorrhoid Treatment, Numb520, Comfort Candy Hemorrhoidal, Tina Davies Icejelly Hemorrhoidal, Tina Davies Icecream Hemorrhoidal, Rrhoid Rage Hemorrhoidal
Methodology & AI Transparency ⓘ
Lidocaine, Phenylephrine Hydrochloride Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Uses –Helps relieve the pain, itching, and burning associated with hemorrhoids.
- 2 Real-world patient consensus: Tracked across 6 patient dosage logs with a 77% satisfaction benchmark (RxCUI 2673304).
- 3 Typical cash cost range: Public pharmacy ledger: $12.50 low cash benchmark vs. $34.50 chain retail average ($0.0989/unit CMS NADAC).
- 4 Top reported side effects / signs: Key post-marketing and trial adverse reactions (Lidocaine, Phenylephrine Hydrochloride): pruritus (5.4%), peripheral edema (5.1%), nausea (8.6%).
Ask our AI Specialists anything about Lidocaine, Phenylephrine Hydrochloride
Lidocaine, Phenylephrine Hydrochloride Mechanism, CYP450 Pathways & DailyMed Monograph
Uses –Helps relieve the pain, itching, and burning associated with hemorrhoids. –Temporarily reduce the swelling associated with irritated hemorrhoidal tissue and other anorectal disorders. –Temporarily provides a coating for relief of anorectal discomforts. –Temporarily protects irritated areas and inflamed perianal skin.
In clinical regimens (40 mg/g / 2.5 mg/g Ointment, 5 g/100mL / .25 g/100mL Cream), Lidocaine, Phenylephrine Hydrochloride executes amide local anesthetic target modulation documented under federal RxCUI 2673304 and DailyMed 2025-05-27 labeling.
Following administration (40 mg/g / 2.5 mg/g Ointment), Lidocaine, Phenylephrine Hydrochloride achieves < 5% transdermal or mucosal systemic uptake from Lidocaine, Phenylephrine Hydrochloride bioavailability and initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (lidocaine, phenylephrine hydrochloride) onset, governed by a Localized tissue retention for Lidocaine, Phenylephrine Hydrochloride with minimal systemic plasma half-life terminal half-life through local esterase/enzymatic cleavage of lidocaine, phenylephrine hydrochloride with minimal hepatic cytochrome burden.
Before initiating Lidocaine, Phenylephrine Hydrochloride at 40 mg/g / 2.5 mg/g Ointment, clinical safety checklists rule out severe drug-induced hypersensitivity to lidocaine, phenylephrine hydrochloride or inactive tablet/vehicle binders; prohibited co-prescriptions or physiological states specified in fda spl 2025-05-27 for lidocaine, phenylephrine hydrochloride. Logged tolerability patterns center on nausea (8.6% of reports), headache (8.2% of reports), dizziness (6.7% of reports).
Assess baseline hepatic panels and interacting prescriptions when starting Lidocaine, Phenylephrine Hydrochloride (amide local anesthetic).
Botanical enzyme modulators may alter oral first-pass exposure of Lidocaine, Phenylephrine Hydrochloride; disclose all supplements.
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- Severe drug-induced hypersensitivity to Lidocaine, Phenylephrine Hydrochloride or inactive tablet/vehicle binders
- Prohibited co-prescriptions or physiological states specified in FDA SPL 2025-05-27 for Lidocaine, Phenylephrine Hydrochloride
Logged Side-Effect Incidence (6 Reports)
Lidocaine, Phenylephrine Hydrochloride Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Lidocaine, Phenylephrine Hydrochloride)
Human clinical trial evidence for Lidocaine, Phenylephrine Hydrochloride is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .
Lidocaine, Phenylephrine Hydrochloride Public Price Transparency Ledger
| Dispensing Channel / Benchmark | Verification Source | Reference Cost | Details |
|---|---|---|---|
| Pharmacy Acquisition Cost (CMS NADAC) | CMS Medicaid NADAC Weekly National Survey | $0.0989/unit (~$2.97/30u) | Wholesale baseline |
| Average U.S. Walk-In Retail Cash Price | Chain Pharmacy Uninsured Cash Index | $34.50 / mo | Before coupon/insurance |
| Patient-Logged Out-of-Pocket Average | 6 Anonymous DotMD Community Micro-Logs | $12.50 / mo | View logs ↓ |
Lidocaine, Phenylephrine Hydrochloride Federal Verification & Benchmark Summary
| Metric | Verified Benchmark | Source |
|---|---|---|
| Lidocaine, Phenylephrine Hydrochloride RxNorm Concept ID | 2673304 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0989 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $34.50 / mo | U.S. Uninsured Retail Cash Index |
| Public Mail-Order Wholesale Benchmark | $12.50 / mo (Patient Mean) | Public Cash Reference |
| Real-World Patient Consensus | 77.00% Worth It (6 anonymous logs) | DotMD Zero-PHI Patient Ledger |
Lidocaine, Phenylephrine Hydrochloride Patient Community, Cohort Filters & Dosage Logs
Evidence synthesis for Lidocaine, Phenylephrine Hydrochloride: FDA labeling (2025-05-27, NDC 82433-946), CYP/interaction screening, and public pharmacy acquisition costs.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Filter Lidocaine, Phenylephrine Hydrochloride community threads and patient logs by age, biological sex, dosage, and treatment duration.