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IBS, Crohn, Colitis & Bowel Disorders • ICD-10-CM K64.9

Hemorrhoids

Also known as: Piles

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM K64.9 • 4 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hemorrhoids Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Hemorrhoids?

What are hemorrhoids? Hemorrhoids are swollen, inflamed veins around your anus or the lower part of your rectum . There are two types: External hemorrhoids, which form under the skin around your anus Internal hemorrhoids, which form in the lining of your anus and lower rectum What causes hemorrhoids? Hemorrhoids happen when there is too much pressure on the veins around the anus. This can be caused by: Straining during bowel movements . Sitting on the toilet for long periods of time. Chronic constipation or diarrhea . A low- fiber diet. Weakening of the supporting tissues in your anus and rectum. This can happen with aging and pregnancy .

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Hemorrhoids (K64.9) features mucosal tight-junction permeability in Hemorrhoids (K64.9: shifts or immune-mediated). Cross-referenced with NIH MeSH (Hemorrhoids), therapeutic stabilization in ibs, ibd & colon is verified against hs-CRP, CBC & in Hemorrhoids (K64.9: Ferritin).

Common Symptoms & Clinical Signs

  • • External hemorrhoids, which form under the skin around your anus
  • • Internal hemorrhoids, which form in the lining of your anus and lower rectum
  • • Presentation of Hemorrhoids (K64.9): alternating diarrhea, constipation, in Hemorrhoids (K64.9: urgency, or sensation)
  • • Secondary Hemorrhoids clinical sign: post-meal abdominal distension, in Hemorrhoids (K64.9: gas bloating, or)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Hemorrhoids Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code K64.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub IBS, Crohn, Colitis & Bowel Disorders NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Tissue Transglutaminase IgA in Hemorrhoids (K64.9: (tTG-IgA)) Negative (celiac rule-out) (K64.9) Clinical Reference Target Range
Diagnostic / Lab Marker: hs-CRP, CBC & in Hemorrhoids (K64.9: Ferritin) Normal hemoglobin; hs-CRP < 1.0 mg/L (K64.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Fecal Calprotectin [Hemorrhoids K64.9] < 50 mcg/g (K64.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Hemorrhoids

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Lidocaine HCl and Hydrocortisone Acetate Lidocaine HCl - Hydrocortisone Acetate, Lidocaine HCl 3% and Hydrocortisone Acetate1% Cream • RxCUI 1012223 Amide Local Anesthetic 78% $0.8747 $ 43.93 /mo
Lidocaine 4% Relaxink Lidocaine, Healthwise Lidocaine Pain Relief • RxCUI 1421893 Amide Local Anesthetic 77% $0.0989 $ 12.50 /mo
Hydrocortisone Acetate Medi-First Hydrocortisone 1%, Medi First Plus • RxCUI 1291082 Corticosteroid 88% $0.0537 $ 6.55 /mo
Lidocaine, Phenylephrine Hydrochloride The Femme Fix Hemorrhoid Treatment, Numb520 • RxCUI 2673304 Amide Local Anesthetic 77% $0.0989 $ 12.50 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hemorrhoids)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Urgency Numeric Rating Scale: Psychometric Evaluation in Adults with Crohn's

The Urgency NRS demonstrated strong psychometric properties in the VIVID-1 population of moderately to severely active CD.

Advances in therapy • 2025-02-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 39692838 ↗
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Hemorrhoids Patient Community & “People Like Me” Threads

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