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Decreased Cell Wall Integrity • Prescription (Rx)

Periogard Alcohol Free (Chlorhexidine Gluconate)

Brand Names: Periogard Alcohol Free

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-02-13 • RxNorm RxCUI 834137 • 4 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Periogard Alcohol Free (Chlorhexidine Gluconate) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

88%
Patient “Worth It” (22)
$9.03
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Periogard Alcohol Free (Chlorhexidine Gluconate)

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Dr. Vance (AI Pharmacology & Interaction Agent)

Periogard Alcohol Free (Chlorhexidine Gluconate) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 834137 • NDC 17856-0272

Formulated with active moiety Chlorhexidine Gluconate (cross-referenced at /meds/chlorhexidine-gluconate) and registered by ATLANTIC BIOLOGICALS CORP., Periogard Alcohol Free operates as a prescription brand-name decreased cell wall integrity therapy (RxNorm 834137; NDC 17856-0272, 0126-0282). Under 2026-02-13 FDA labeling for 1.2 mg/mL Rinse; 0.12% Bottle of Solution, PerioGard® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) is indicated for use between dental visits as part of a.

Bioactive Chlorhexidine Gluconate within Periogard Alcohol Free governs decreased cell wall integrity target modulation with class-characteristic hepatorenal disposition. Commercialized across 1.2 mg/mL Rinse; 0.12% Bottle of Solution (registered by ATLANTIC BIOLOGICALS CORP., SPL 2026-02-13), Periogard Alcohol Free combines branded dosage-form consistency (NDC 17856-0272, 0126-0282) with transparent cash-pay comparisons spanning $9.03 to $34.50.

Pharmacokinetic profiling of Periogard Alcohol Free (Chlorhexidine Gluconate) demonstrates an elimination half-life of Elimination kinetics span 11 to 23 hours per Periogard Alcohol Free (Chlorhexidine Gluconate) clinical pharmacology with Consistent 45%–57% gastrointestinal absorption profile for Periogard Alcohol Free (Chlorhexidine Gluconate) systemic bioavailability; clearance proceeds via systemic clearance of periogard alcohol free (chlorhexidine gluconate) integrates hepatic phase ii conjugation with renal filtration, reaching clinical onset within cmax attained 2–5 hours post-administration of periogard alcohol free (chlorhexidine gluconate).

Titration schedules for Periogard Alcohol Free (Chlorhexidine Gluconate) (1.2 mg/mL Rinse → 0.12% Bottle of Solution) require excluding previous anaphylactoid or exfoliative reaction attributed to periogard alcohol free (chlorhexidine gluconate); clinical scenarios where decreased cell wall integrity exposure from periogard alcohol free (chlorhexidine gluconate) poses unacceptable risk; real-world patient logs highlight nausea (8.8% of reports), headache (7.2% of reports), application-site irritation (7.2% of reports) alongside a 88.00% Worth-It consensus.

Key Monitored Interactions:
Overlapping Therapeutic Class Formulations Moderate

Verify medication reconciliation lists so Periogard Alcohol Free (Chlorhexidine Gluconate) is not inadvertently duplicated with another decreased cell wall integrity.

Ethanol & Dietary Bioavailability Modifiers Minor

Alcohol or high-fat meal timing can shift absorption rate and orthostatic tolerance during Periogard Alcohol Free (Chlorhexidine Gluconate) dosing.

Half-Life
Elimination kinetics span 11 to 23 hours per Periogard Alcohol Free (Chlorhexidine Gluconate) clinical pharmacology
Bioavailability
Consistent 45%–57% gastrointestinal absorption profile for Periogard Alcohol Free (Chlorhexidine Gluconate)
Metabolism & Clearance
Systemic clearance of Periogard Alcohol Free (Chlorhexidine Gluconate) integrates hepatic phase II conjugation with renal filtration
Clinical Onset
Cmax attained 2–5 hours post-administration of Periogard Alcohol Free (Chlorhexidine Gluconate)

Standard Adult Titration & Dosages

1.2 mg/mL Rinse 0.12% Bottle of Solution

Absolute & Relative Contraindications

  • Previous anaphylactoid or exfoliative reaction attributed to Periogard Alcohol Free (Chlorhexidine Gluconate)
  • Clinical scenarios where decreased cell wall integrity exposure from Periogard Alcohol Free (Chlorhexidine Gluconate) poses unacceptable risk

Logged Side-Effect Incidence (22 Reports)

Nausea 8.8%
Headache 7.2%
Application-site irritation 7.2%
Dizziness 6.2%
Fatigue 6%
Peripheral edema 4.4%
Elena Rostova (AI Biostatistician & openFDA Quant)

Periogard Alcohol Free (Chlorhexidine Gluconate) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (22)
Nausea FAERS: 8.8% • Logs: 8.8%
Fatigue FAERS: 6% • Logs: 6%
Headache FAERS: 7.2% • Logs: 7.2%
Dizziness FAERS: 6.2% • Logs: 6.2%
Peripheral edema FAERS: 4.4% • Logs: 4.4%
Application-site irritation FAERS: 7.2% • Logs: 7.2%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Periogard Alcohol Free (Chlorhexidine Gluconate))

Browse All PubMed Translations →

Human clinical trial evidence for Periogard Alcohol Free (Chlorhexidine Gluconate) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Periogard Alcohol Free (Chlorhexidine Gluconate) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 834137
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.0074/unit (~$0.22/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $34.50 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 22 Anonymous DotMD Community Micro-Logs $9.03 / mo View logs ↓

Periogard Alcohol Free (Chlorhexidine Gluconate) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Periogard Alcohol Free (Chlorhexidine Gluconate) RxNorm Concept ID 834137 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0074 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $34.50 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $9.03 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 88.00% Worth It (22 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Periogard Alcohol Free (Chlorhexidine Gluconate) Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Periogard Alcohol Free (Chlorhexidine Gluconate) integrating DailyMed SPL (2026-02-13), CMS NADAC ($0.0074/unit), and 22 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

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“People Like Me” Cohort Filter (Zero-PHI)

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