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ADHD, Autism & Behavioral Health • ICD-10-CM F50.0

Alcohol Use Disorder (AUD)

Also known as: Alcohol abuse, Alcohol dependence, Alcoholism

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM F50.0 • 8 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Alcohol Use Disorder (AUD) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Alcohol Use Disorder (AUD)?

What is alcohol use disorder (AUD)? For most adults, moderate alcohol use is probably not harmful. Your risk of developing an alcohol use disorder (AUD) depends on how much, how often, and how quickly you drink alcohol. Alcohol misuse means that drinking causes distress and harm. Over time alcohol misuse can increase your risk of AUD. AUD can range from mild to severe, depending on the symptoms. Severe AUD is sometimes called alcoholism or alcohol dependence.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Alcohol Use Disorder (AUD) (ICD-10 F50.0) is driven by norepinephrine alpha-2A) receptor in Alcohol Use Disorder (AUD) (F50.0: under-signaling across executive-control); Cross-referenced with NIH MeSH (Alcoholism), specialists in ADHD, Autism & Behavioral Health monitor Resting Blood Pressure in Alcohol Use Disorder (AUD) (F50.0: & Pulse (on) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Craving - a strong need to drink
  • • Loss of control - not being able to stop drinking once you've started
  • • Presentation of Alcohol Use Disorder (AUD) (F50.0): internal restlessness, impulsive in Alcohol Use Disorder (AUD) (F50.0: interrupting, or emotional)
  • • Secondary Alcohol Use Disorder (AUD) clinical sign: compulsive reward-seeking behaviors in Alcohol Use Disorder (AUD) (F50.0: or difficulty moderating)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Alcohol Use Disorder (AUD) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code F50.0 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub ADHD, Autism & Behavioral Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: ASRS-v1.1 / Vanderbilt in Alcohol Use Disorder (AUD) (F50.0: Executive Score) Functional symptom control (F50.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Resting Blood Pressure in Alcohol Use Disorder (AUD) (F50.0: & Pulse (on) < 125/80 mmHg; HR < 85 bpm (F50.0) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Ferritin & in Alcohol Use Disorder (AUD) (F50.0: Iron Saturation) Ferritin 50 – 120 ng/mL (F50.0) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Alcohol Use Disorder (AUD)

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Periogard Alcohol Free (Chlorhexidine Gluconate) Periogard Alcohol Free • RxCUI 834137 Decreased Cell Wall Integrity 88% $0.0074 $ 9.03 /mo
Disulfiram Antabuse • RxCUI 197623 Aldehyde Dehydrogenase Inhibitor 86% $1.5721 $ 61.66 /mo
Umcka Coldcare Alcohol-Free (Pelargonium Sidoides) Umcka Coldcare Alcohol-Free • RxCUI RXN-B534995271 Over-the-Counter Clinical Monograph 88% $0.4700 $ 42.34 /mo
Alcohol Plus Brasept Alcocol Gel, Servo-Stat • RxCUI 2048982 Over-the-Counter Clinical Monograph 87% $0.0139 $ 9.06 /mo
Orajel Toothache Rinse (Benzyl Alcohol, Zinc Chloride) Orajel Toothache Rinse • RxCUI 1865199-B10237764 Pediculicide 89% $3.0200 $ 225.94 /mo
Vivitrol (Naltrexone) Vivitrol • RxCUI 1483744-B65757300 Alcohol Dependence Agent 86% $1622.1365 $ 640.00 /mo
Genuine First Aid Alcohol Cleansing Pad (Benzocaine, Alcohol) Genuine First Aid Alcohol Cleansing Pad • RxCUI 1046313-B50814080 Standardized Chemical Allergen 76% $2.9300 $ 219.46 /mo
Physostigmine Salicylate Anticholium • RxCUI 2666367 FDA Prescription Therapeutic Agent 94% $0.2200 $ 17.41 /mo
Plus Brasept Alcocol Gel (Alcohol) Plus Brasept Alcocol Gel • RxCUI 581662 Over-the-Counter Clinical Monograph 93% $0.0139 $ 9.50 /mo
Itch X (Benzyl Alcohol/Pramoxine Hydrochloride) Itch X • RxCUI 1293634 Pediculicide 87% $2.6100 $ 196.42 /mo
Naltrexone Hydrochloride ReVia • RxCUI 1483744 Opioid Antagonist 83% $1.1231 $ 22.94 /mo
Solucion Antiseptica Dermoxine (Solucion Antiseptica Topica A Base De Alcohol Etilico) Solucion Antiseptica Dermoxine • RxCUI RXN-B58345106 Decreased Cell Wall Integrity 91% $3.1300 $ 233.86 /mo
Emory Johns Creek Amenity (Alcohol and Sodium Monofluorophospate) Emory Johns Creek Amenity • RxCUI 545626 Over-the-Counter Clinical Monograph 94% $0.0139 $ 9.50 /mo
Goodsense Artifical Tears (Polyvinyl Alcohol, and Povidone) Goodsense Artifical Tears • RxCUI 598050-B63187893 Over-the-Counter Clinical Monograph 78% $0.3521 $ 33.85 /mo
Orajel 2x Gum Pain Alcohol-Free (Menthol and Hydrogen Peroxide) Orajel 2x Gum Pain Alcohol-Free • RxCUI 2584344 Over-the-Counter Clinical Monograph 77% $0.8804 $ 71.89 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Alcohol Use Disorder (AUD))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on GLP-1 receptor agonists on the degree of liver fibrosis and CRP in non-alcoholic: What a 2,178-Participant Study Found

This study evaluated the efficacy of GLP-1RAs in patients with NAFLD and NASH.

Primary care diabetes • 2024-06-15 • Meta-Analysis
N = 2,178 99/100 PMID 38555202 ↗
New Insights on Effects of glucagon-like peptide-1 receptor agonists (GLP1-RAs) on: What a 430-Participant Study Found

Observational studies suggest a decrease in alcohol-related events, but RCTs have effects on alcohol consumption and craving that remain non-significant.

Addiction science & clinical practice • 2025-12-05 • Meta-Analysis
N = 430 97/100 PMID 41350683 ↗
New Insights on Cenicriviroc Lacked Efficacy to Treat Liver Fibrosis in Nonalcoholic: What a 1,778-Participant Study Found

This study did not demonstrate the efficacy of CVC for treating liver fibrosis assessed by histology in adults with NASH; however, CVC was safe and well tolerated in patients with NASH and liver fibrosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association • 2024-01-15 • Phase III Randomized Trial
N = 1,778 96/100 PMID 37061109 ↗
New Insights on Low-dose ondansetron: A candidate prospective precision medicine to treat alcohol: What a 303-Participant Study Found

In this Phase 3 clinical trial, AD04 was shown to be a promising treatment for currently drinking heavy drinking individuals with AUD who also possess a specific genotypic profile in the serotonin transporter and serotonin-3AB...

European journal of internal medicine • 2024-09-15 • Phase III Randomized Trial
N = 303 93/100 PMID 38876929 ↗
New Insights on Resmetirom for nonalcoholic fatty liver disease: a randomized, gold-standard: What a 325-Participant Study Found

These findings demonstrate resmetirom was safe and well tolerated in adults with presumed NASH, supporting a role for further clinical development.

Nature medicine • 2023-11-15 • Phase III Randomized Trial
N = 325 93/100 PMID 37845512 ↗
Zero-PHI Patient Support & Cohort Discussions

Alcohol Use Disorder (AUD) Patient Community & “People Like Me” Threads

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