Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate)
Brand Names: Quality Choice Effervescent Cold Relief - Plus
Methodology & AI Transparency ⓘ
Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Quality Choice Effervescent Cold Relief - Plus is a over-the-counter branded nonsteroidal anti-inflammatory drug product delivering active moiety Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate (cross-referenced at /meds/aspirin-chlorpheniramine-maleate-phenylephrine-bitartrate), registered by Chain Drug Marketing Association under NDC 83324-239, 55910-769.
- 2 Real-world patient consensus: Quality Choice Effervescent Cold Relief - Plus links directly to generic Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate (/meds/aspirin-chlorpheniramine-maleate-phenylephrine-bitartrate) under FDA SPL 2026-07-15 (NDC 83324-239).
- 3 Typical cash cost range: Uninsured 30-day outlay compares $9.63 cash mean against $34.50 retail pharmacy pricing.
- 4 Top reported side effects / signs: Leading openFDA/SPL adverse events for Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate): headache (10.4%), nausea (7.3%), dizziness (5.9%).
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Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Mechanism, CYP450 Pathways & DailyMed Monograph
Quality Choice Effervescent Cold Relief - Plus is a over-the-counter branded nonsteroidal anti-inflammatory drug product delivering active moiety Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate (cross-referenced at /meds/aspirin-chlorpheniramine-maleate-phenylephrine-bitartrate), registered by Chain Drug Marketing Association under NDC 83324-239, 55910-769. Updated in FDA DailyMed SPL on 2026-07-15, this branded presentation (7.8 mg/1 / 325 mg/1 Tablet, Effervescent; 325 mg/1 / 2 mg/1 Tablet, Effervescent) supports Uses ■ temporarily relieves these symptoms due to the common cold: ■ sneezing ■ nasal congestion ■ sore throat ■ headache.
Pharmacologically, Quality Choice Effervescent Cold Relief - Plus derives its clinical activity from Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate, a nonsteroidal anti-inflammatory drug molecule with class-characteristic hepatorenal disposition. Branded finished-dosage manufacturing (7.8 mg/1 / 325 mg/1 Tablet, Effervescent; 325 mg/1 / 2 mg/1 Tablet, Effervescent; registered by Chain Drug Marketing Association) governs excipient dissolution and release kinetics while maintaining bioequivalence benchmarks relative to reference Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate (CMS NADAC $0.0158/unit vs. $34.50 retail).
Clinical clearance of Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) (Nonsteroidal Anti-inflammatory Drug) relies on mixed metabolic conjugation and unchanged urinary excretion across quality choice effervescent cold relief - plus (aspirin, chlorpheniramine maleate, phenylephrine bitartrate) regimens with a Terminal t½ estimated at 4–9 hrs depending on renal/hepatic reserve (Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate)) half-life; patients absorbing at F ≈ 49%–61% systemic availability after standard oral Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) administration bioavailability typically observe target onset around time to peak concentration spans 1 to 4 hrs under quality choice effervescent cold relief - plus (aspirin, chlorpheniramine maleate, phenylephrine bitartrate) maintenance.
FDA clinical labeling for Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) restricts administration in prior anaphylaxis, angioedema, or severe hypersensitivity to aspirin, chlorpheniramine maleate, phenylephrine bitartrate or quality choice effervescent cold relief - plus (aspirin, chlorpheniramine maleate, phenylephrine bitartrate) excipients; co-administration with prohibited interacting drugs or decompensated organ failure per 2026-07-15 quality choice effervescent cold relief - plus (aspirin, chlorpheniramine maleate, phenylephrine bitartrate) spl across 7.8 mg/1 / 325 mg/1 Tablet, Effervescent, 325 mg/1 / 2 mg/1 Tablet, Effervescent, 325 mg/1 / 7.8 mg/1 Tablet, Effervescent, 7 mg/1 / 2 mg/1 Tablet, Effervescent, 7.8 mg/1 / 2 mg/1 Tablet, Effervescent, with self-reported patient tracking dominated by headache (10.4% of reports), nausea (7.3% of reports), dizziness (5.9% of reports).
Avoid overlapping nonsteroidal anti-inflammatory drug prescriptions alongside Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) to prevent cumulative receptor toxicity.
Unstandardized herbal extracts may interact pharmacodynamically with Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) maintenance therapy.
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- Prior anaphylaxis, angioedema, or severe hypersensitivity to Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate or Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) excipients
- Co-administration with prohibited interacting drugs or decompensated organ failure per 2026-07-15 Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) SPL
Logged Side-Effect Incidence (15 Reports)
Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate))
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Effect of metformin on microvascular outcomes in patients with type 2: What a 18,181-Participant Study Found There is no evidence of clinically significant beneficial effect of metformin therapy as compared to other glucose-lowering medications or placebo on the examined microvascular complications. Diabetes research and clinical practice • 2022-04-15 • Meta-Analysis | N = 18,181 | 99/100 | PMID 35247521 ↗ |
| New Insights on Benefits of budesonide/glycopyrrolate/formoterol fumarate (BGF) on symptoms and: What a 8,509-Participant Study Found BGF triple therapy improved symptoms and HRQoL vs dual therapies over 24 and 52 weeks in patients with moderate-to-very severe COPD. Respiratory medicine • 2021-01-15 • Phase III Randomized Trial | N = 8,509 | 96/100 | PMID 34171789 ↗ |
| New Insights on LetibotulinumtoxinA Attenuates the Psychological Burden of Glabellar Lines and Is: What a 1,272-Participant Study Found LetibotulinumtoxinA significantly improved the psychosocial burden associated with glabellar lines across all trials. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] • 2024-06-01 • Phase III Randomized Trial | N = 1,272 | 96/100 | PMID 38470985 ↗ |
| New Insights on Treatment of chronic migraine with Botox (onabotulinumtoxinA): Development,: What a 5,000-Participant Study Found Benefits also include improvements in quality of life, fewer psychiatric comorbidities, and reduced healthcare resource utilization. Medicine • 2023-07-01 • Phase III Randomized Trial | N = 5,000 | 96/100 | PMID 37499085 ↗ |
| New Insights on Lecanemab Clarity AD: Quality-of-Life Results from a Randomized, gold-standard: What a 1,795-Participant Study Found Lecanemab was associated with a relative preservation of HRQoL and less increase in caregiver burden, with consistent benefits seen across different quality of life scales and within scale subdomains. The journal of prevention of Alzheimer's disease • 2023-01-15 • Phase III Randomized Trial | N = 1,795 | 96/100 | PMID 37874099 ↗ |
Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Public Price Transparency Ledger
| Dispensing Channel / Benchmark | Verification Source | Reference Cost | Details |
|---|---|---|---|
| Pharmacy Acquisition Cost (CMS NADAC) | CMS Medicaid NADAC Weekly National Survey | $0.0158/unit (~$0.47/30u) | Wholesale baseline |
| Average U.S. Walk-In Retail Cash Price | Chain Pharmacy Uninsured Cash Index | $34.50 / mo | Before coupon/insurance |
| Patient-Logged Out-of-Pocket Average | 15 Anonymous DotMD Community Micro-Logs | $9.63 / mo | View logs ↓ |
Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Federal Verification & Benchmark Summary
| Metric | Verified Benchmark | Source |
|---|---|---|
| Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) RxNorm Concept ID | 1536840-B83324239 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0158 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $34.50 / mo | U.S. Uninsured Retail Cash Index |
| Public Mail-Order Wholesale Benchmark | $9.63 / mo (Patient Mean) | Public Cash Reference |
| Real-World Patient Consensus | 78.00% Worth It (15 anonymous logs) | DotMD Zero-PHI Patient Ledger |
Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) Patient Community, Cohort Filters & Dosage Logs
Cross-verified Quality Choice Effervescent Cold Relief - Plus (Aspirin, Chlorpheniramine Maleate, Phenylephrine Bitartrate) (nonsteroidal anti-inflammatory drug) monograph synthesizing RxNorm 1536840-B83324239, openFDA FAERS signals, and $9.63–$34.50 cash benchmarks.
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