Pelvic Inflammatory Disease
Also known as: PID, Pelvis, Pelvic, Pelvo
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Pelvic Inflammatory Disease Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: What is pelvic inflammatory disease? Pelvic inflammatory disease (PID) is an infection of the uterus, ovaries, and other female reproductive organs.
- 2 Real-world patient consensus: Synonyms for Pelvic Inflammatory Disease (N73.9): PID, Pelvis, Pelvic (OB/GYN & PCOS).
- 3 Typical cash cost range: Clinicians assessing Pelvic Inflammatory Disease focus on ovarian theca-cell hyperandrogenism in Pelvic Inflammatory Disease (N73.9: amplified by hyperinsulinemia) and targeted history.
- 4 Top reported side effects / signs: Key OB/GYN & PCOS biomarkers for Pelvic Inflammatory Disease (N73.9): Free & Total in Pelvic Inflammatory Disease (N73.9: Testosterone + SHBG) & Fasting Insulin & in Pelvic Inflammatory Disease (N73.9: HbA1c) (Fasting insulin < 8 uIU/mL (N73.9)).
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What Is Pelvic Inflammatory Disease?
What is pelvic inflammatory disease? Pelvic inflammatory disease (PID) is an infection of the uterus, ovaries, and other female reproductive organs. PID causes scarring in these organs. This can lead to infertility , ectopic pregnancy , pelvic pain, abscesses (a collection of pus), and other serious problems. PID is the most common preventable cause of infertility in the United States. What causes pelvic inflammatory disease? Many types of bacteria can cause PID, but it's often caused by sexually transmitted infections (STIs). Gonorrhea and chlamydia are the most common causes of PID. You are at greater risk for PID if you: Are sexually active and younger than age 25.
Pathophysiology, Underlying Causes & Clinical Presentation
Pelvic Inflammatory Disease (N73.9) alters ob/gyn & pcos homeostasis through ovarian theca-cell hyperandrogenism in Pelvic Inflammatory Disease (N73.9: amplified by hyperinsulinemia); Cross-referenced with NIH MeSH (Pelvic Inflammatory Disease), clinical remission targets Fasting Insulin & in Pelvic Inflammatory Disease (N73.9: HbA1c) within Fasting insulin < 8 uIU/mL (N73.9).
Common Symptoms & Clinical Signs
- • Are sexually active and younger than age 25
- • Have more than one sex partner
- • Presentation of Pelvic Inflammatory Disease (N73.9): irregular, infrequent, or in Pelvic Inflammatory Disease (N73.9: absent ovulatory menstrual)
- • Secondary Pelvic Inflammatory Disease clinical sign: severe pelvic cramping [Pelvic Inflammatory Disease N73.9]
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Pelvic Inflammatory Disease Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | N73.9 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | PCOS, Endometriosis & Gynecologic Health | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: Free & Total in Pelvic Inflammatory Disease (N73.9: Testosterone + SHBG) | Sex-specific physiological range (N73.9) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Fasting Insulin & in Pelvic Inflammatory Disease (N73.9: HbA1c) | Fasting insulin < 8 uIU/mL (N73.9) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: CBC & Serum in Pelvic Inflammatory Disease (N73.9: Ferritin (heavy bleeding)) | Ferritin > 50 ng/mL (N73.9) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Pelvic Inflammatory Disease
| Medication | Pharmacologic Class | Patient Worth-It | CMS NADAC / Unit | Typical Lowest Cash |
|---|---|---|---|---|
| Diphenhydramine HCl, Ibuprofen Advil Pm • RxCUI RXN-05730148-2215 | Nonsteroidal Anti-inflammatory Drug | 82% | $0.0159 | $ 9.15 /mo |
| Betamethasone Dipropionate Sernivo, Diprolene • RxCUI 848178 | Corticosteroid | 74% | $0.4641 | $ 8.74 /mo |
| Treximet (Sumatriptan Succinate and Naproxen Sodium) Treximet • RxCUI 849450-B42847850 | Nonsteroidal Anti-inflammatory Drug | 86% | $16.3139 | $ 185.70 /mo |
| Bromsite (Bromfenac) Bromsite • RxCUI 578018-B49708754 | Nonsteroidal Anti-inflammatory Drug | 80% | $49.5434 | $ 640.00 /mo |
| Tobradex St (Tobramycin / Dexamethasone) Tobradex St • RxCUI 1011080 | Aminoglycoside Antibacterial | 84% | $46.6196 | $ 640.00 /mo |
| Clotrimazole/Betameth Clotrimazole/Betameth Generic • RxCUI RXN-72189518-1106 | Azole Antifungal | 84% | $0.5160 | $ 29.40 /mo |
| Lidocaine HCl and Hydrocortisone Acetate Lidocaine HCl - Hydrocortisone Acetate, Lidocaine HCl 3% and Hydrocortisone Acetate1% Cream • RxCUI 1012223 | Amide Local Anesthetic | 78% | $0.8747 | $ 43.93 /mo |
| Diphenhydramine Citrate and Ibuprofen Advil Pm • RxCUI RXN-852371784-2172 | Nonsteroidal Anti-inflammatory Drug | 90% | $0.0159 | $ 9.15 /mo |
| Lidocaine HCl 3% and Hydrocortisone Acetate 0.5% Cream (Lidocaine HCl and Hydrocortisone Acetate) Lidocaine HCl 3% and Hydrocortisone Acetate 0.5% Cream • RxCUI RXN-B59088721 | Amide Local Anesthetic | 89% | $0.0989 | $ 15.62 /mo |
| Diclofenac Potassium 25 Mg Diclofenac Potassium 25 Mg Generic • RxCUI RXN-59088131-2542 | Nonsteroidal Anti-inflammatory Drug | 90% | $2.6951 | $ 117.65 /mo |
| Norgesic (Orphenadrine Citrate, Aspirin and Caffeine) Norgesic • RxCUI RXN-B61825305 | Nonsteroidal Anti-inflammatory Drug | 91% | $5.8031 | $ 426.32 /mo |
| Aspirin Drug Mart Effervescent Pain Relief, Wispirin • RxCUI 198467 | Nonsteroidal Anti-inflammatory Drug | 82% | $0.0253 | $ 5.98 /mo |
| Bc Max (Aspirin, Acetaminophen, Caffeine) Bc Max • RxCUI 2360605-B63029203 | Nonsteroidal Anti-inflammatory Drug | 80% | $0.0667 | $ 13.30 /mo |
| Lurbiro (Flurbiprofen) Lurbiro • RxCUI 197724-B71085082 | Nonsteroidal Anti-inflammatory Drug | 94% | $3.1677 | $ 236.57 /mo |
| Ibuprofen Pm (Diphenhydramine Citrate, Ibuprofen) Ibuprofen Pm • RxCUI 895664-B30142050 | Nonsteroidal Anti-inflammatory Drug | 83% | $0.0159 | $ 9.65 /mo |
| Fluocinol Pak (Fluocinonide) Fluocinol Pak • RxCUI 485647-B59088755 | Corticosteroid | 81% | $0.3206 | $ 31.58 /mo |
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Pelvic Inflammatory Disease)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Six Decades of Pelvic Exenterative Surgery for Gynaecological: What a 13,434-Participant Study Found PE carries substantial morbidity, while perioperative mortality was approximately 5% overall and 3.7% in post-2005 studies. In vivo (Athens, Greece) • 2026-01-15 • Meta-Analysis | N = 13,434 | 94/100 | PMID 42957251 ↗ |
| New Insights on Responsiveness and thresholds for clinically meaningful changes in worst pain: What a 871-Participant Study Found Based on these results, clinically meaningful changes were defined as a reduction of 4 points for NRS-DYS and 2 points for NRS-NMPP. Fertility and sterility • 2021-02-15 • Phase III Randomized Trial | N = 871 | 93/100 | PMID 33066973 ↗ |
| New Insights on Effect of Pelvic External Beam Radiation Therapy on Bone Mineral Density: A: What a 447-Participant Study Found We did not find sufficient evidence to suggest any detrimental effect of pelvic XRT on the treatment effect from denosumab on percent BMD change, with only an approximately 5% incidence of clinical fractures. International journal of radiation oncology, biology, physics • 2024-05-01 • Phase III Randomized Trial | N = 447 | 93/100 | PMID 37924987 ↗ |
| New Insights on Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy: What a 300-Participant Study Found This RCT confirms that EPLND provides better pathological staging, while differences in early oncological outcomes were not demonstrated. European urology • 2021-05-15 • Phase III Randomized Trial | N = 300 | 87/100 | PMID 33293077 ↗ |
| Can This Approach Help? Inside the Latest Research on Late Urinary Toxicity and Quality of Life With Pelvic Radiation Therapy for During long-term follow-up, whole pelvic radiation therapy resulted in low (∼5%) and similar grade 3 cumulative urinary toxicity as prostate-only radiation therapy. International journal of radiation oncology, biology, physics • 2024-10-01 • Phase III Randomized Trial | Multi-cohort | 82/100 | PMID 38552989 ↗ |
Pelvic Inflammatory Disease Patient Community & “People Like Me” Threads
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