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Official NIH NLM MEDLINE / PubMed Citation • PMID: 36558392 • DOI: 10.3390/nu14245235

A Magtein®, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults.

Nutrients • 2022 Dec • Vol. 14 (24) • ISSN 2072-6643
Authors: Chengxiang Zhang, Qi Hu, Shifen Li, Feifei Dai, Wen Qian, Susan Hewlings, Ting Yan, Yubang Wang
The Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, China.

Verbatim Formal Study Abstract

ABSTRACT

Magnesium is one of the most abundant essential minerals in the body. Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesium compound, magnesium L-threonate (Magtein®) was identified and was shown to raise the magnesium levels in the brain and neurons effectively. In this double-blind, placebo-controlled study, Magtein®PS, a magnesium L-threonate (Magtein®)- and phosphatidylserine-based formulation additionally containing vitamins C and D, was tested for its cognitive benefits in 109 healthy Chinese adults aged 18-65 years. Subjects were randomly assigned to receive either Magtein®PS or placebo (starch) capsules, at a dose of 2 g/day. "The Clinical Memory Test", the standard test commonly used in Chinese hospitals and academic institutes for cognitive evaluation, was administered before and 30 days after subjects received the supplement. Subjects receiving Magtein®PS showed significant improvements over the control group in all five subcategories of "The Clinical Memory Test" as well as the overall memory quotient scores. The older participants showed more improvement than younger participants. Results indicated significant benefits of Magtein®PS in improving memory and cognition in healthy Chinese adults.

Publication Classification: Randomized Controlled Trial Journal Article
NLM MeSH Descriptors: Humans Adult Magnesium East Asian People Brain Cognition Dietary Supplements Double-Blind Method Butyrates