✓ Translated by DotMD AI Clinical Council Source: International journal of urology : official journal of the Japanese Urological Association • Randomized Controlled Trial
Verify Primary Source: NIH PubMed PMID #22958078 ↗

Randomized Controlled Trial: Tadalafil once daily for lower urinary tract symptoms suggestive of benign prostatic hyperplasia (N = 154)

Original Paper Title: “Tadalafil once daily for lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a randomized placebo- and tamsulosin-controlled 12-week study in Asian men”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
N = 154
Evidence Classification
Randomized Controlled Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • Tadalafil once daily represents an effective and well tolerated medical treatment for Asian men presenting with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
  • Study Design & Sample: Randomized Controlled Trial published in International journal of urology : official journal of the Japanese Urological Association (N = 154 human participants).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in International journal of urology : official journal of the Japanese Urological Association (2013), this randomized controlled trial evaluating 154 human participants investigated: To examine the efficacy and safety of tadalafil in Asian men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Key clinical takeaway: Tadalafil once daily represents an effective and well tolerated medical treatment for Asian men presenting with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (International journal of urology : official journal of the Japanese Urological Association, 2013-02-15; N = 154; Rigor 88/100): Tadalafil once daily represents an effective and well tolerated medical treatment for Asian men presenting with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Randomized Controlled Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

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