What ferritin level should I aim for with hair shedding and fatigue, and is iron bisglycinate enough?
Ferritin is the standard blood test for iron stores. Many labs flag below 15 ng/mL as low, but the AGA 2020 guideline suggests below 45 ng/mL is a more sensitive cutoff for iron deficiency. Some dermatology sources suggest keeping ferritin above 40 ng/mL for hair shedding, but the evidence is mixed. Ferritin also rises with inflammation, so a value of 60 ng/mL with high CRP can still hide low stores. Check hemoglobin, transferrin saturation (below 20% suggests deficiency) and CRP alongside it. Iron bisglycinate at 25-30 mg elemental iron once daily or every other day is often better tolerated than 65 mg ferrous sulfate. Expect hemoglobin to rise in 2-4 weeks and ferritin to rebuild over 8-12 weeks. Unexplained iron deficiency, especially in men or postmenopausal women, needs a clinician workup for blood loss.
The AGA 2020 iron deficiency anemia guideline supports a ferritin cutoff of 45 ng/mL for diagnosing deficiency. The levothyroxine DailyMed label advises separating it from iron and calcium products by at least 4 hours.