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★ "What Worked For Me" Outcome Report @ThyroidMorning_CA • 30-44F • 400mg riboflavin / 300mg ele • Week 16

▲ 38 Helpful • 2 Peer Replies

Riboflavin 400 mg AM + Mg glycinate evening (16 wks update): I started at 10 attack days a month with 8 triptan days — what worked for others here?

I started at 10 attack days a month with 8 triptan days. Month 1 gave little change. Magnesium oxide gave me diarrhea, so I switched to glycinate and the issue resolved. By week 12, attack days were down to 5 and triptan days to 4. I added CoQ10 ubiquinol 100 mg twice daily at week 6 with food. I kept a diary of attacks, sleep hours and cycle days. I also checked my kidney function with my clinician before raising the magnesium dose. The biggest practical gains were consistent timing and the 12-week patience window. This is my experience, not a recommendation.

⚕ Pinned FDA / NIH / PubMed Clinical Context • Priya Nair — Literature & Label Auditor

A randomized trial of CoQ10 300 mg/day (100 mg three times daily) reported a 50% responder rate of 47.6% versus 14.4% on placebo (Sandor 2005, n=42). Riboflavin 400 mg/day and magnesium are both rated Level B by the AAN/AHS guideline.

Connected Clinical Guides: Condition: Migraine Condition: Tension Headache Rx: Sumatriptan Rx: Rizatriptan Supplement: Magnesium Glycinate Supplement: Riboflavin (Vitamin B2)

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Verified Peer Replies (2)

@EveningWalk_VA • Verified Cohort Member • Week 22

Good structure: single changes with dates make results interpretable. Adding CoQ10 at week 6 makes it harder to attribute the benefit, so consider noting that in your diary. CoQ10 is fat-soluble, so taking it with a meal helps absorption. Ubiquinol and ubiquinone have both been used in studies.

@RefluxReset_MA • Age 45-59 • Week 20

Similar story here. Switching from oxide to glycinate fixed my stomach issues, and splitting magnesium into two smaller doses helped. I also stopped judging at week 4 and waited until week 12 to compare my diary.