★ "What Worked For Me" Outcome Report @MaintenanceMode_WA • 45-59M • Losartan 50mg (from Lisinopr • Week 10

▲ 52 Helpful • 2 Peer Replies

Lisinopril 20 mg to Losartan 50 mg, BMP at week 2 (10 wks update): Male, 52, hypertension — what worked for others here?

Male, 52, hypertension. I had a dry cough on lisinopril 20 mg for about 4 months, and it got worse when lying down. My doctor stopped lisinopril and started losartan 50 mg the next morning, taken at the same time daily. Changes I tracked: week 1, cough unchanged; week 3, about 60% better; week 6, gone. My BMP at week 2 showed potassium 4.4 mEq/L and creatinine 1.0 mg/dL, matching baseline. My home BP average (validated upper-arm cuff, 2 readings, 7 days) went from 136/86 on lisinopril to 129/82 on losartan. I did not add potassium supplements or salt substitute. If you are on losartan, bring a symptom log and lab dates to your follow-up. Cough persisting beyond 3 months should prompt a review for other causes such as reflux, asthma, or lung issues.

⚕ Pinned FDA / NIH / PubMed Clinical Context • Priya Nair — Literature & Label Auditor

ACE inhibitor cough is a class effect from bradykinin accumulation, and ARB cough rates are close to placebo (FDA DailyMed losartan label; PubMed meta-analyses of ARB tolerability). The losartan label advises monitoring serum potassium and creatinine after starting therapy, particularly in renal impairment.

Connected Clinical Guides: Condition: Hypertension Condition: Heart Failure Rx: Lisinopril Rx: Losartan Supplement: Magnesium Glycinate Supplement: Potassium Citrate

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Verified Peer Replies (2)

@NorthWoodsLabs_WI • Verified Cohort Member • Week 16

Good protocol. One addition: a persistent cough alongside weight gain, ankle swelling, or exertional breathlessness should be checked for heart failure rather than assumed to be a drug effect. Ask for a chest exam and consider BNP if those symptoms accompany it.

@OzarkCyclist_MO • Age 60+ • Week 14

Same switch for me, lisinopril 10 mg to losartan 50 mg. My cough took about 5 weeks to clear fully. I kept a simple log with daily cough score from 0 to 5, which helped my doctor see the trend instead of relying on memory.