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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L70.2

Acne varioliformis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L70.2 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Acne varioliformis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Acne varioliformis?

Acne varioliformis is an ICD-10-CM indexed diagnosis (L70.2) within Dermatology: Acne, Eczema, Psoriasis & Rosacea. Clinical evaluation centers on dermoscopy or punch in Acne varioliformis (L70.2: biopsy when atypical) alongside serial Fasting Lipids & in Acne varioliformis (L70.2: ALT (if systemic) tracking (Within baseline reference limits (L70.2)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Acne varioliformis (ICD-10 L70.2) is driven by or pilosebaceous follicular in Acne varioliformis (L70.2: hyperkeratinization); specialists in Dermatology: Acne, Eczema, Psoriasis & Rosacea monitor 25-Hydroxy Vitamin D in Acne varioliformis (L70.2: & hs-CRP) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Acne varioliformis (L70.2): persistent erythematous plaques, in Acne varioliformis (L70.2: scaly patches, pruritic)
  • • Secondary Acne varioliformis clinical sign: compromised epidermal barrier in Acne varioliformis (L70.2: with dryness, fissuring,)
  • • Symptom flares in Acne varioliformis correlating with Fasting Lipids & in Acne varioliformis (L70.2: ALT (if systemic) deviation outside Within baseline reference limits (L70.2)
  • • Functional skin & dermatology impact requiring dermoscopy or punch in Acne varioliformis (L70.2: biopsy when atypical) evaluation (L70.2)

Acne varioliformis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L70.2 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NLM Clinical Tables
Diagnostic / Lab Marker: Fasting Lipids & in Acne varioliformis (L70.2: ALT (if systemic) Within baseline reference limits (L70.2) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Acne varioliformis (L70.2: & hs-CRP) 25(OH)D 40–65 ng/mL (L70.2) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Acne varioliformis (L70.2: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L70.2) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Acne varioliformis

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Acne varioliformis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Skin-applied tazarotene in the treatment of mild to moderate: What a 468-Participant Study Found

In general, 'using the cream formulation rather than the gel formulation optimized tolerability.

Cutis • 2004-10-15 • Meta-Analysis
N = 468 97/100 PMID 15543714 ↗
New Insights on Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients: What a 1,614-Participant Study Found

Once-daily treatment with tazarotene 0.045% polymeric emulsion lotion may help improve patient-perceived skin oiliness in those with moderate-to-severe acne.

The Journal of dermatological treatment • 2023-12-15 • Randomized Controlled Trial
N = 1,614 96/100 PMID 36382987 ↗
New Insights on Janus kinase inhibitors and side effects of acne in dermatologic: What a 11,396-Participant Study Found

Conclusions: There are higher rates of acne following treatment with JAK inhibitors for dermatologic indications, particularly with longer durations and larger dosages.

The Journal of dermatological treatment • 2024-12-15 • Meta-Analysis
N = 11,396 94/100 PMID 39218446 ↗
New Insights on Gold-standard blind, vehicle-controlled, multicenter comparison of two 0.025%: What a 271-Participant Study Found

The commercially-available 0.025% tretinoin cream and the 0.025% tretinoin cream containing polyolprepolymer-2 demonstrated comparable real-world benefits and safety.

Journal of the American Academy of Dermatology • 1998-04-15 • Randomized Controlled Trial
N = 271 93/100 PMID 9555823 ↗
New Insights on Efficacy and Tolerability of a Novel Tretinoin 0.05% Lotion for the Once-Daily: What a 551-Participant Study Found

Conclusions: Tretinoin 0.05% lotion was significantly more effective than vehicle in achieving treatment success and reducing inflammatory and noninflammatory lesions in adult females with moderate acne, with notable...

Journal of drugs in dermatology : JDD • 2019-11-01 • Randomized Controlled Trial
N = 551 93/100 PMID 31741360 ↗
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