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Cancer, Oncology & Supportive Care • ICD-10-CM D36.9

Benign Tumors

Also known as: Benign neoplasms, Noncancerous tumors, Neoplasia, Growth, Neoplasm

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM D36.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Benign Tumors Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Benign Tumors?

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain. Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them. When cells grow old, they die, and new cells take their place. Sometimes, this process goes wrong. New cells form when your body does not need them, and old cells do not die when they should. These extra cells can divide without stopping and may form a tumor.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Benign Tumors (ICD-10 D36.9) is driven by angiogenesis [Benign Tumors D36.9]; Cross-referenced with NIH MeSH (Papilloma, Fibroma), specialists in Cancer, Oncology & Supportive Care monitor Complete Blood Count in Benign Tumors (D36.9: (ANC, Hemoglobin, Platelets)) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Benign Tumors (D36.9): abnormality detected early in Benign Tumors (D36.9: on age-appropriate screening)
  • • Secondary Benign Tumors clinical sign: persistent painless lump, in Benign Tumors (D36.9: non-healing ulcer/mole change,)
  • • Symptom flares in Benign Tumors correlating with Pathology / Molecular in Benign Tumors (D36.9: Genomic Staging) deviation outside Guideline-concordant surveillance (D36.9)
  • • Functional cancer & oncology impact requiring multidisciplinary tumor-board planning in Benign Tumors (D36.9: (surgery) evaluation (D36.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Benign Tumors Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code D36.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Pathology / Molecular in Benign Tumors (D36.9: Genomic Staging) Guideline-concordant surveillance (D36.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in Benign Tumors (D36.9: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (D36.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Benign Tumors (D36.9: Organ Function Panel) Preserved renal/hepatic clearance (D36.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Benign Tumors

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Dutasteride and Tamsulosin Hydrochloride Jalyn • RxCUI 996097 5-alpha Reductase Inhibitor 85% $1.8643 $ 84.00 /mo
68ga-Dotatate Netspot • RxCUI RXN-69488001-1794 FDA Prescription Therapeutic Agent 93% $1.3200 $ 61.96 /mo
Terazosin Hydrochloride Hytrin • RxCUI 260376 alpha-Adrenergic Blocker 78% $0.1246 $ 7.45 /mo
Tezruly (Terazosin) Tezruly • RxCUI 260376-B70954592 alpha-Adrenergic Blocker 76% $0.1246 $ 17.47 /mo
Alfuzosin Hydrochloride Alfuzosin Hydrochloride Generic • RxCUI 861132 alpha-Adrenergic Blocker 75% $0.1047 $ 12.74 /mo
Lomustine Gleostine • RxCUI 197894 Alkylating Drug 83% $0.5700 $ 31.58 /mo
Doxazosin Cardura • RxCUI 197626 alpha-Adrenergic Blocker 81% $0.0580 $ 5.74 /mo
Nirogacestat Ogsiveo • RxCUI 2680360 Gamma Secretase Inhibitor 89% $0.7600 $ 39.28 /mo
Tamsulosin Hydrochloride Flomax • RxCUI 863669 alpha-Adrenergic Blocker 90% $0.0515 $ 6.01 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Benign Tumors)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Baseline Total Testosterone Level on Successful Treatment of Sexual Dysfunction: What a 1,075-Participant Study Found

Low TT levels at baseline did not negatively influence response to tadalafil in men of advancing age with concomitant lower urinary tract symptoms and benign prostatic hyperplasia and erectile dysfunction.

The journal of sexual medicine • 2016-05-15 • Randomized Controlled Trial
N = 1,075 96/100 PMID 27017071 ↗
New Insights on Development and validation of a multivariable prognostic model in de novo: What a 1,058-Participant Study Found

A prognostic model for men with de novo mCSPC was developed and validated in an independent testing set.

Prostate cancer and prostatic diseases • 2023-03-15 • Phase III Randomized Trial
N = 1,058 96/100 PMID 35790787 ↗
New Insights on Benefits and safety of Combination Comprising Tamsulosin and PDE5-Is, Relative to: What a 1,144-Participant Study Found

However, therapy discontinuation due to pain and AEs did not increase with increase in AEs.

American journal of men's health • 2020-01-15 • Meta-Analysis
N = 1,144 94/100 PMID 33342335 ↗
New Insights on Monotherapies and Combination Therapy of Tamsulosin and Tadalafil for Treating: What a 1,531-Participant Study Found

Tadalafil combined with tamsulosin was more effective in the treatment of male LUTS/BPH, with or without ED, on the improvement of total IPSS, QoL, and Qmax.

Urologia internationalis • 2024-01-15 • Meta-Analysis
N = 1,531 94/100 PMID 38081154 ↗
New Insights on Tadalafil on nighttime voiding (nocturia) in men with lower urinary tract: What a 752-Participant Study Found

A statistically significant improvement in nocturnal frequency was seen with tadalafil over placebo; however, the treatment difference was small and not considered clinically meaningful.

World journal of urology • 2014-10-15 • Randomized Controlled Trial
N = 752 93/100 PMID 24504761 ↗
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