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Depression, Bipolar & Mood Disorders • ICD-10-CM F31.71

Bipolar disorder, in partial remission, most recent episode hypomanic

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM F31.71 • 7 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Bipolar disorder, in partial remission, most recent episode hypomanic Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Bipolar disorder, in partial remission, most recent episode hypomanic?

Bipolar disorder, in partial remission, most recent episode hypomanic is an ICD-10-CM indexed diagnosis (F31.71) within Depression, Bipolar & Mood Disorders. Clinical evaluation centers on validated longitudinal mood in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: rating scales (PHQ-9) alongside serial Serum Vitamin D in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: & RBC Folate) tracking (25(OH)D 40 – 65 ng/mL (F31.71)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

In Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71), physiological disruption stems from prefrontal-limbic circuit dysregulation [Bipolar disorder, in partial remission, most recent episode hypomanic F31.71], informing Depression, Bipolar & Mood Disorders protocols that track PHQ-9 Symptom Severity in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: Score) (< 4 (clinical remission) (F31.71)).

Common Symptoms & Clinical Signs

  • • Presentation of Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71): disrupted sleep architecture [Bipolar disorder, in partial remission, most recent episode hypomanic F31.71]
  • • Secondary Bipolar disorder, in partial remission, most recent episode hypomanic clinical sign: slowed concentration, indecisiveness, in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: and physical heaviness)
  • • Symptom flares in Bipolar disorder, in partial remission, most recent episode hypomanic correlating with Serum Vitamin D in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: & RBC Folate) deviation outside 25(OH)D 40 – 65 ng/mL (F31.71)
  • • Functional depression & mood impact requiring validated longitudinal mood in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: rating scales (PHQ-9) evaluation (F31.71)

Bipolar disorder, in partial remission, most recent episode hypomanic Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code F31.71 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Depression, Bipolar & Mood Disorders NLM Clinical Tables
Diagnostic / Lab Marker: Serum Vitamin D in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: & RBC Folate) 25(OH)D 40 – 65 ng/mL (F31.71) Clinical Reference Target Range
Diagnostic / Lab Marker: PHQ-9 Symptom Severity in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: Score) < 4 (clinical remission) (F31.71) Clinical Reference Target Range
Diagnostic / Lab Marker: TSH & Free in Bipolar disorder, in partial remission, most recent episode hypomanic (F31.71: T4 Rule-Out) TSH 0.8 – 2.5 mIU/L (F31.71) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Bipolar disorder, in partial remission, most recent episode hypomanic)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Antidepressants for the treatment of adults with depression in the maintenance: What a 9,384-Participant Study Found

Compared to placebo, venlafaxine was associated with a lower incidence of dizziness, while desvenlafaxine, sertraline, and vortioxetine were associated with a higher incidence of nausea/vomiting.

Molecular psychiatry • 2023-01-15 • Meta-Analysis
N = 9,384 99/100 PMID 36253442 ↗
New Insights on Efficacy of Lumateperone in Patients With Bipolar Depression With Mixed: What a 376-Participant Study Found

Conclusions: Lumateperone 42 mg significantly improved symptoms of depression and disease severity in patients with an MDE associated with bipolar I or bipolar II disorder, with or without mixed features.

The Journal of clinical psychiatry • 2023-04-24 • Phase III Randomized Trial
N = 376 93/100 PMID 37103915 ↗
Does negative affectivity predict differential response to an SSRI versus a non-SSRI antidepressant?

These data suggest that patients with high negative affectivity respond preferentially to antidepressants that selectively enhance serotonin neurotransmission.

The Journal of clinical psychiatry • 2014-09-15 • Randomized Controlled Trial
N = 245 88/100 PMID 25295437 ↗
Can This Approach Help? Inside the Latest Research on Duration of Adjunctive Antidepressant Maintenance in Bipolar I

In a trial involving patients with bipolar I disorder and a recently remitted depressive episode, adjunctive treatment with escitalopram or bupropion XL that continued for 52 weeks did not show a significant benefit as...

The New England journal of medicine • 2023-08-03 • Randomized Controlled Trial
N = 90 88/100 PMID 37530824 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of Lumateperone for Major Depressive Episodes Associated With

Lumateperone at 42 mg/day significantly improved depression symptoms and was generally well tolerated in patients with major depressive episodes associated with both bipolar I and bipolar II disorders.

The American journal of psychiatry • 2021-12-15 • Phase III Randomized Trial
N = 188 88/100 PMID 34551584 ↗
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