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Chronic Kidney Disease & Electrolytes • ICD-10-CM N00.4

Dehydration

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM N00.4 • 5 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Dehydration Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Dehydration?

What is dehydration? Dehydration is a condition caused by the loss of too much fluid from the body . It happens when you are losing more fluids than you are taking in, and your body does not have enough fluids to work properly. What causes dehydration? You can become dehydrated because of: Diarrhea Vomiting Sweating too much Urinating too much, which can happen because of certain medicines and illnesses Fever Not drinking enough water or other fluids Who is more likely to develop dehydration? Certain people are more likely to develop dehydration: Older adults. Some people lose their sense of thirst as they age, so they don't drink enough fluids.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Dehydration (ICD-10 N00.4) is driven by glomerular capillary hyperfiltration in Dehydration (N00.4: barotrauma); Cross-referenced with NIH MeSH (Dehydration), specialists in Chronic Kidney Disease & Electrolytes monitor eGFR (Creatinine + in Dehydration (N00.4: Cystatin C)) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Urinating too much, which can happen because of certain medicines and illnesses
  • • Not drinking enough water or other fluids
  • • Presentation of Dehydration (N00.4): asymptomatic decline in in Dehydration (N00.4: eGFR or persistent)
  • • Secondary Dehydration clinical sign: fluid retention in in Dehydration (N00.4: ankles, hands, or)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Dehydration Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code N00.4 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Chronic Kidney Disease & Electrolytes NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Serum Potassium, Bicarbonate in Dehydration (N00.4: & Phosphorus) K+ 3.8–4.8 mEq/L; HCO3 23–29 mEq/L (N00.4) Clinical Reference Target Range
Diagnostic / Lab Marker: eGFR (Creatinine + in Dehydration (N00.4: Cystatin C)) >= 90 mL/min/1.73m2 (N00.4) Clinical Reference Target Range
Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio in Dehydration (N00.4: (uACR)) < 15 mg/g (< 30 mg/g normal) (N00.4) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Dehydration

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Treatment selection for Dehydration depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Dehydration)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Clinical and nutritional correlates of bacterial diarrhoea aetiology in young: What a 6,692-Participant Study Found

The presence of MAM, dehydration or high stool frequency may be helpful in identifying children with MSD who might benefit from antibiotics.

BMJ paediatrics open • 2024-04-11 • Phase III Randomized Trial
N = 6,692 90/100 PMID 38604769 ↗
Can This Approach Help? Inside the Latest Research on Effect of losartan and amlodipine on proteinuria and transforming growth

Losartan and amlodipine, with similar control of BP, showed different effects on urine protein or TGF-beta1 excretion.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2003-06-15 • Randomized Controlled Trial
N = 20 82/100 PMID 12748343 ↗
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Dehydration Patient Community & “People Like Me” Threads

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