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Men's Health, Testosterone & Sexual Function • ICD-10-CM N52.01

Erectile dysfunction due to arterial insufficiency

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM N52.01 • 7 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Erectile dysfunction due to arterial insufficiency Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Erectile dysfunction due to arterial insufficiency?

Erectile dysfunction due to arterial insufficiency—coded clinically as N52.01 across Men's Health & TRT guidelines—combines PDE5 vascular therapy [Erectile dysfunction due to arterial insufficiency N52.01] with structured follow-up of Morning Total & in Erectile dysfunction due to arterial insufficiency (N52.01: Free Testosterone (2x) (Total 500–900 ng/dL; Free 110–210 pg/mL (N52.01)).

Pathophysiology, Underlying Causes & Clinical Presentation

Erectile dysfunction due to arterial insufficiency (N52.01) alters men's health & trt homeostasis through microvascular arterial inflow in Erectile dysfunction due to arterial insufficiency (N52.01: reduction); clinical remission targets Morning Total & in Erectile dysfunction due to arterial insufficiency (N52.01: Free Testosterone (2x) within Total 500–900 ng/dL; Free 110–210 pg/mL (N52.01).

Common Symptoms & Clinical Signs

  • • Presentation of Erectile dysfunction due to arterial insufficiency (N52.01): blunted motivation, depressed in Erectile dysfunction due to arterial insufficiency (N52.01: mood, or declining)
  • • Secondary Erectile dysfunction due to arterial insufficiency clinical sign: two consecutive morning in Erectile dysfunction due to arterial insufficiency (N52.01: total testosterone readings)
  • • Symptom flares in Erectile dysfunction due to arterial insufficiency correlating with Ultrasensitive Estradiol & in Erectile dysfunction due to arterial insufficiency (N52.01: ApoB) deviation outside E2 20–38 pg/mL; ApoB < 80 mg/dL (N52.01)
  • • Functional men's health & trt impact requiring PDE5 vascular therapy [Erectile dysfunction due to arterial insufficiency N52.01] evaluation (N52.01)

Erectile dysfunction due to arterial insufficiency Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code N52.01 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Men's Health, Testosterone & Sexual Function NLM Clinical Tables
Diagnostic / Lab Marker: Ultrasensitive Estradiol & in Erectile dysfunction due to arterial insufficiency (N52.01: ApoB) E2 20–38 pg/mL; ApoB < 80 mg/dL (N52.01) Clinical Reference Target Range
Diagnostic / Lab Marker: Morning Total & in Erectile dysfunction due to arterial insufficiency (N52.01: Free Testosterone (2x) Total 500–900 ng/dL; Free 110–210 pg/mL (N52.01) Clinical Reference Target Range
Diagnostic / Lab Marker: LH, FSH & in Erectile dysfunction due to arterial insufficiency (N52.01: SHBG) LH/FSH 2.5 – 8.0 mIU/mL (N52.01) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Erectile dysfunction due to arterial insufficiency

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Iohexol Omnipaque • RxCUI RXN-808302466-1733 Radiographic Contrast Agent 83% $0.6200 $ 33.61 /mo
Epinephrine Adrenalin, Neffy • RxCUI 1660014 alpha-Adrenergic Agonist 86% $127.8321 $ 185.00 /mo
Iopamidol Isovue 200, Isovue • RxCUI RXN-02701314-1729 Radiographic Contrast Agent 81% $0.2400 $ 18.22 /mo
Ethiodized Oil Lipiodol • RxCUI RXN-676841901-2887 Radiographic Contrast Agent 84% $2.8400 $ 123.52 /mo
Iopromide Ultravist • RxCUI RXN-50419348-2522 Radiographic Contrast Agent 88% $3.4300 $ 147.42 /mo
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Erectile dysfunction due to arterial insufficiency)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Testosterone Therapy for Late-Onset Hypogonadism Improves Erectile: What a 1,458-Participant Study Found

TTh achieved a significant improvement in the IIEF-EFD score of hypogonadal men compared with placebo, especially in those who received testosterone gel, were treated for over 30 weeks, and had no comorbidities.

Urologia internationalis • 2022-01-15 • Meta-Analysis
N = 1,458 99/100 PMID 34856556 ↗
New Insights on Benefits and safety of Combination Comprising Tamsulosin and PDE5-Is, Relative to: What a 1,144-Participant Study Found

However, therapy discontinuation due to pain and AEs did not increase with increase in AEs.

American journal of men's health • 2020-01-15 • Meta-Analysis
N = 1,144 94/100 PMID 33342335 ↗
New Insights on Monotherapies and Combination Therapy of Tamsulosin and Tadalafil for Treating: What a 1,531-Participant Study Found

Tadalafil combined with tamsulosin was more effective in the treatment of male LUTS/BPH, with or without ED, on the improvement of total IPSS, QoL, and Qmax.

Urologia internationalis • 2024-01-15 • Meta-Analysis
N = 1,531 94/100 PMID 38081154 ↗
Combination Therapies vs. Single-drug treatment: Which Works Better for Erectile Dysfunction?

A total of 44 studies included 3853 men with a mean (SD) age of 55.8 (11.9) years.

JAMA network open • 2021-02-01 • Meta-Analysis
N = 3,853 94/100 PMID 33599772 ↗
New Insights on Benefits and safety of tadalafil 5 mg once-daily in Asian men with both lower: What a 361-Participant Study Found

Tadalafil is efficacious and well tolerated in the treatment of Asian men with both lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction.

International journal of urology : official journal of the Japanese Urological Association • 2019-02-15 • Phase III Randomized Trial
N = 361 93/100 PMID 30362173 ↗
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