High Cholesterol in Children and Teens
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High Cholesterol in Children and Teens Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: What is cholesterol? Cholesterol is a waxy, fat-like substance that's found in all the cells in the body.
- 2 Real-world patient consensus: Federal ICD-10-CM code E78.1 categorizes High Cholesterol in Children and Teens under Cholesterol, Triglycerides & Lipids.
- 3 Typical cash cost range: Differential triage of High Cholesterol in Children and Teens (E78.1) utilizes hepatic transaminase baseline in High Cholesterol in Children and Teens (E78.1: checks).
- 4 Top reported side effects / signs: Longitudinal High Cholesterol in Children and Teens monitoring tracks Apolipoprotein B (ApoB) [High Cholesterol in Children and Teens E78.1] toward < 70 mg/dL (< 55 mg/dL high risk) (E78.1).
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What Is High Cholesterol in Children and Teens?
What is cholesterol? Cholesterol is a waxy, fat-like substance that's found in all the cells in the body. The liver makes cholesterol, and it is also in some foods, such as meat and dairy products. The body needs some cholesterol to work properly. But if your child or teen has high cholesterol (too much cholesterol in the blood), it can stick to the walls of their arteries and narrow or even block the arteries. This can put your child or teen at risk of coronary artery disease and other heart diseases .
Pathophysiology, Underlying Causes & Clinical Presentation
In High Cholesterol in Children and Teens (E78.1), physiological disruption stems from subendothelial ApoB retention [High Cholesterol in Children and Teens E78.1], Cross-referenced with NIH MeSH (Hypercholesterolemia), informing Cholesterol, Triglycerides & Lipids protocols that track LDL Cholesterol [High Cholesterol in Children and Teens E78.1] (< 85 mg/dL (E78.1)).
Common Symptoms & Clinical Signs
- • An unhealthy diet, especially one that is high in saturated fats
- • A family history of high cholesterol, especially when one or both parents have high cholesterol
- • Presentation of High Cholesterol in Children and Teens (E78.1): premature family history in High Cholesterol in Children and Teens (E78.1: of coronary stenting,)
- • Secondary High Cholesterol in Children and Teens clinical sign: achilles tendon thickening, in High Cholesterol in Children and Teens (E78.1: xanthelasma, or premature)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
High Cholesterol in Children and Teens Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | E78.1 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Cholesterol, Triglycerides & Lipids | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: Apolipoprotein B (ApoB) [High Cholesterol in Children and Teens E78.1] | < 70 mg/dL (< 55 mg/dL high risk) (E78.1) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: LDL Cholesterol [High Cholesterol in Children and Teens E78.1] | < 85 mg/dL (E78.1) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Fasting Triglycerides [High Cholesterol in Children and Teens E78.1] | < 100 mg/dL (E78.1) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for High Cholesterol in Children and Teens
Treatment selection for High Cholesterol in Children and Teens depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.
Peer-Reviewed Human Clinical Trials & Meta-Analyses (High Cholesterol in Children and Teens)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Achieved blood pressure and heart and blood vessel outcomes in high-risk: What a 8,407-Participant Study Found Mean achieved SBP less than 120 mm Hg during treatment was associated with increased risk of heart and blood vessel outcomes except for heart attack and stroke. Lancet (London, England) • 2017-06-03 • Meta-Analysis | N = 8,407 | 99/100 | PMID 28390695 ↗ |
| New Insights on Major outcomes in high-risk hypertensive patients randomized to: What a 9,048-Participant Study Found Thiazide-type diuretics are superior in preventing 1 or more major forms of CVD and are less expensive. JAMA • 2002-12-18 • Randomized Controlled Trial | N = 9,048 | 96/100 | PMID 12479763 ↗ |
| New Insights on Heart and blood vessel outcomes in high-risk hypertensive patients stratified by: What a 8,126-Participant Study Found Older high-risk patients with high blood pressure and reduced GFR are more likely to develop CHD than to develop ESRD. Annals of internal medicine • 2006-02-07 • Randomized Controlled Trial | N = 8,126 | 96/100 | PMID 16461961 ↗ |
| New Insights on Glucose levels predict hospitalization for congestive heart failure in patients: What a 25,620-Participant Study Found Fasting plasma glucose is an independent predictor of hospitalization for CHF in high-risk subjects. Circulation • 2007-03-20 • Randomized Controlled Trial | N = 25,620 | 96/100 | PMID 17339550 ↗ |
| New Insights on Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus: What a 2,959-Participant Study Found Ezetimibe/simvastatin was more effective than rosuvastatin in LDL-C lowering, and provided greater or comparable improvements in other lipid measures and hsCRP at the approved usual starting, next highest, and maximum doses in... Current medical research and opinion • 2006-10-15 • Randomized Controlled Trial | N = 2,959 | 96/100 | PMID 17022864 ↗ |
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