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Cancer, Oncology & Supportive Care • ICD-10-CM C84.00

Mycosis fungoides

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C84.00 • 7 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Mycosis fungoides Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Mycosis fungoides?

Mycosis fungoides is an ICD-10-CM indexed diagnosis (C84.00) within Cancer, Oncology & Supportive Care. Clinical evaluation centers on radiation) paired with in Mycosis fungoides (C84.00: proactive supportive symptom) alongside serial Complete Blood Count in Mycosis fungoides (C84.00: (ANC, Hemoglobin, Platelets)) tracking (Safe hematologic reserve (C84.00)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Mycosis fungoides (C84.00) features tumor-suppressor loss enabling in Mycosis fungoides (C84.00: clonal proliferation). therapeutic stabilization in cancer & oncology is verified against Comprehensive Metabolic & in Mycosis fungoides (C84.00: Organ Function Panel).

Common Symptoms & Clinical Signs

  • • Presentation of Mycosis fungoides (C84.00): unintended weight loss [Mycosis fungoides C84.00]
  • • Secondary Mycosis fungoides clinical sign: unexplained bleeding, chronic in Mycosis fungoides (C84.00: hoarseness/cough, or progressive)
  • • Symptom flares in Mycosis fungoides correlating with Complete Blood Count in Mycosis fungoides (C84.00: (ANC, Hemoglobin, Platelets)) deviation outside Safe hematologic reserve (C84.00)
  • • Functional cancer & oncology impact requiring radiation) paired with in Mycosis fungoides (C84.00: proactive supportive symptom) evaluation (C84.00)

Mycosis fungoides Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C84.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NLM Clinical Tables
Diagnostic / Lab Marker: Complete Blood Count in Mycosis fungoides (C84.00: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C84.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Mycosis fungoides (C84.00: Organ Function Panel) Preserved renal/hepatic clearance (C84.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Mycosis fungoides (C84.00: Genomic Staging) Guideline-concordant surveillance (C84.00) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Mycosis fungoides

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Treatment selection for Mycosis fungoides depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Mycosis fungoides)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Skin-applied Efinaconazole 10% for Onychomycosis: Pooled Phase 3 Analysis in: What a 1,655-Participant Study Found

Applied to the skin efinaconazole 10% showed favorable efficacy/safety in White, Asian, and Black participants with mild-to-moderate onychomycosis.

Journal of drugs in dermatology : JDD • 2026-01-01 • Phase III Randomized Trial
N = 1,655 96/100 PMID 41493257 ↗
New Insights on Estimating the Impact of Adjuvant Treatment With Nivolumab on Long-Term: What a 709-Participant Study Found

Adjuvant NIVO for high-risk MIUC was associated with a higher cure fraction than PBO in the ITT and PD-L1 ≥1% populations.

Clinical genitourinary cancer • 2025-06-15 • Phase III Randomized Trial
N = 709 93/100 PMID 40204616 ↗
New Insights on Quality-adjusted survival in patients with metastatic colorectal cancer treated: What a 461-Participant Study Found

Fruquintinib provides a clinically meaningful quality-adjusted survival benefit versus placebo in refractory mCRC.

ESMO open • 2025-03-15 • Phase III Randomized Trial
N = 461 93/100 PMID 39985889 ↗
New Insights on Idasanutlin plus cytarabine in relapsed or refractory acute myeloid leukemia:: What a 447-Participant Study Found

Common any-grade side effects (≥10% incidence in any arm) were diarrhea (87.0% vs 32.9%), febrile neutropenia (52.8% vs 49.3%), and nausea (52.5% vs 31.5%).

Blood advances • 2022-07-26 • Phase III Randomized Trial
N = 447 93/100 PMID 35413116 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of Efinaconazole 10% skin-applied Solution for Treatment of

Efinaconazole 10% solution showed similar efficacy/safety in participants aged ≥ 65 years to the overall phase 3 population, despite potential age-related nail changes.

Mycoses • 2025-05-15 • Phase III Randomized Trial
N = 162 88/100 PMID 40396391 ↗
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