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Chronic Kidney Disease & Electrolytes • ICD-10-CM Q61.02

Polycystic kidney

Also known as: Kidney, Renal, Nephric, Nephron

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM Q61.02 • 8 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Polycystic kidney Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Polycystic kidney?

Under Chronic Kidney Disease & Electrolytes diagnostic criteria (Q61.02), workup for Polycystic kidney (also termed Kidney or Renal) integrates serial eGFR (creatinine in Polycystic kidney (Q61.02: + cystatin C)) with evidence-graded therapy tailored to Urine Albumin-to-Creatinine Ratio in Polycystic kidney (Q61.02: (uACR)) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Polycystic kidney (Q61.02) center on glomerular capillary hyperfiltration in Polycystic kidney (Q61.02: barotrauma). targeted kidney & renal interventions aim to normalize Urine Albumin-to-Creatinine Ratio in Polycystic kidney (Q61.02: (uACR)).

Common Symptoms & Clinical Signs

  • • Presentation of Polycystic kidney (Q61.02): asymptomatic decline in in Polycystic kidney (Q61.02: eGFR or persistent)
  • • Secondary Polycystic kidney clinical sign: fluid retention in in Polycystic kidney (Q61.02: ankles, hands, or)
  • • Symptom flares in Polycystic kidney correlating with Urine Albumin-to-Creatinine Ratio in Polycystic kidney (Q61.02: (uACR)) deviation outside < 15 mg/g (< 30 mg/g normal) (Q61.02)
  • • Functional kidney & renal impact requiring serial eGFR (creatinine in Polycystic kidney (Q61.02: + cystatin C)) evaluation (Q61.02)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Polycystic kidney Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code Q61.02 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Chronic Kidney Disease & Electrolytes NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio in Polycystic kidney (Q61.02: (uACR)) < 15 mg/g (< 30 mg/g normal) (Q61.02) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Potassium, Bicarbonate in Polycystic kidney (Q61.02: & Phosphorus) K+ 3.8–4.8 mEq/L; HCO3 23–29 mEq/L (Q61.02) Clinical Reference Target Range
Diagnostic / Lab Marker: eGFR (Creatinine + in Polycystic kidney (Q61.02: Cystatin C)) >= 90 mL/min/1.73m2 (Q61.02) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Polycystic kidney

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Treatment selection for Polycystic kidney depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Polycystic kidney)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Efficacy of N -Acetylcysteine in Polycystic Ovary Syndrome: Systematic Review and: What a 2,515-Participant Study Found

NAC had a major effect on progesterone, endometrial thickness, and LH levels in women with PCOS.

Nutrients • 2025-01-14 • Meta-Analysis
N = 2,515 99/100 PMID 39861414 ↗
New Insights on Effectiveness of myoinositol for polycystic ovary: What a 573-Participant Study Found

Based on current evidence, myoinositol may be recommended for the treatment of PCOS with insulin resistance, as well as for improving symptoms caused by decreased estrogen in PCOS.

Endocrine • 2018-01-15 • Meta-Analysis
N = 573 97/100 PMID 29052180 ↗
New Insights on Impact of subclinical hypothyroidism on core reproductive hormones and ovarian: What a 3,114-Participant Study Found

Current evidence shows no significant differences in FSH, LH, estradiol, or total testosterone levels between SCH and euthyroid PCOS controls, while the evidence for prolactin.

Frontiers in endocrinology • 2026-01-15 • Meta-Analysis
N = 3,114 94/100 PMID 42798498 ↗
New Insights on Reproductive hormone characteristics of obese Chinese patients with polycystic: What a 4,554-Participant Study Found

Conversely, they exhibited significantly higher testosterone (T) ( p = 0.001) levels.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2025-12-15 • Meta-Analysis
N = 4,554 94/100 PMID 40287875 ↗
New Insights on Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use: What a 257-Participant Study Found

In participants with T2D and CKD, consistent benefits of semaglutide on major kidney outcomes, MACE, and all-cause mortality were observed regardless of baseline MRA use.

Diabetes care • 2025-11-01 • Randomized Controlled Trial
N = 257 93/100 PMID 40730031 ↗
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