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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L08.9

Pustules

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L08.9 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Pustules Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Pustules?

Pustules is an ICD-10-CM indexed diagnosis (L08.9) within Dermatology: Acne, Eczema, Psoriasis & Rosacea. Clinical evaluation centers on dermoscopy or punch in Pustules (L08.9: biopsy when atypical) alongside serial Affected Body Surface in Pustules (L08.9: Area (BSA /) tracking (Clear or Almost Clear (IGA 0–1) (L08.9)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Pustules (code L08.9) is epidermal barrier filaggrin/ceramide in Pustules (L08.9: disruption), which Dermatology: Acne, Eczema, Psoriasis & Rosacea clinicians address while surveilling Affected Body Surface in Pustules (L08.9: Area (BSA /) (Clear or Almost Clear (IGA 0–1) (L08.9)).

Common Symptoms & Clinical Signs

  • • Presentation of Pustules (L08.9): post-inflammatory hyperpigmentation, facial in Pustules (L08.9: flushing, or pitted)
  • • Secondary Pustules clinical sign: recurrent flares triggered in Pustules (L08.9: by UV exposure,)
  • • Symptom flares in Pustules correlating with Affected Body Surface in Pustules (L08.9: Area (BSA /) deviation outside Clear or Almost Clear (IGA 0–1) (L08.9)
  • • Functional skin & dermatology impact requiring dermoscopy or punch in Pustules (L08.9: biopsy when atypical) evaluation (L08.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Pustules Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L08.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Affected Body Surface in Pustules (L08.9: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L08.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Pustules (L08.9: ALT (if systemic) Within baseline reference limits (L08.9) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Pustules (L08.9: & hs-CRP) 25(OH)D 40–65 ng/mL (L08.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Pustules

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Azelaic Acid Azelex, Finacea Foam • RxCUI 1041518 Decreased Protein Synthesis 88% $0.4345 $ 19.02 /mo
Minocycline Hydrochloride Extended-Release Emrosi, Minocin • RxCUI 2706371 Tetracycline-class Drug 75% $0.3622 $ 10.11 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Pustules)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Time to relapse after tildrakizumab withdrawal in patients with

When treatment is interrupted, tildrakizumab provides durable maintenance of efficacy with a median time to loss of PASI 75 response of 5-6 months, irrespective of the dose.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2021-04-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 32979235 ↗
Can This Approach Help? Inside the Latest Research on Liposomal tretinoin for uncomplicated acne

Liposomal encapsulation of tretinoin allows reduction of the concentration of the active agent without a decline in efficacy for acne vulgaris.

The Clinical investigator • 1994-12-15 • Randomized Controlled Trial
N = 20 88/100 PMID 7711421 ↗
Can This Approach Help? Inside the Latest Research on Gold-standard blind multicenter study comparing acitretin-PUVA, etretinate-PUVA

Acitretin-PUVA treatment was significantly superior to placebo-PUVA with respect to several items (decrease in lesional scores after 6 weeks of therapy, number of PUVA exposures, and total dose of UVA until full symptom relief).

Dermatologica • 1988-01-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 2976000 ↗
Can This Approach Help? Inside the Latest Research on Full-body blue light irradiation as treatment for eczema: a randomized

Despite its favorable safety profile and moderate reductions in itch and IL-31 levels, full-body blue light irradiation did not lead to an amelioration of any of the objective measures of AD.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG • 2023-12-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 37814388 ↗
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